Gene Page: CHGB

Summary
GeneID  1114
Symbol  CHGB
Synonyms  SCG1
Description  chromogranin B (secretogranin 1)
See related  HGNC:1930|MIM:118920|Ensembl:ENSG00000089199|HPRD:07512|
Locus tag  -
Gene type  protein-coding
Map location  20pter-p12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies3Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TRIM330.940.93
IREB20.940.96
RSBN10.930.95
MED130.930.95
ZNF1480.930.96
KIAA20220.930.96
AFF40.930.95
SLC38A10.930.96
EPM2AIP10.930.96
ZNF2810.920.94
Top 10 negatively co-expressed genes
FXYD1-0.66-0.85
TSC22D4-0.65-0.77
AF347015.31-0.65-0.84
HSD17B14-0.65-0.77
HEPN1-0.65-0.73
AIFM3-0.64-0.72
MT-CO2-0.64-0.85
ROM1-0.64-0.77
S100B-0.63-0.78
SERPINB6-0.63-0.71
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005179hormone activityTAS3608978 
GO:0005515protein bindingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACACAACAC | ACC | ACC1 | ACCAacetyl-Coenzyme A carboxylase alphaTwo-hybridBioGRID16169070 
ATXN2ATX2 | FLJ46772 | SCA2 | TNRC13ataxin 2Two-hybridBioGRID16169070 
CBFBPEBP2Bcore-binding factor, beta subunitTwo-hybridBioGRID16169070 
CCDC92FLJ22471coiled-coil domain containing 92Two-hybridBioGRID16169070 
FGFR3ACH | CD333 | CEK2 | HSFGFR3EX | JTK4fibroblast growth factor receptor 3Two-hybridBioGRID16169070 
GCS1-glucosidase ITwo-hybridBioGRID16169070 
MARK3CTAK1 | KP78 | PAR1AMAP/microtubule affinity-regulating kinase 3Two-hybridBioGRID16169070 
MGLLHU-K5 | MGLmonoglyceride lipaseTwo-hybridBioGRID16169070 
OGG1HMMH | HOGG1 | MUTM | OGH18-oxoguanine DNA glycosylaseTwo-hybridBioGRID16169070 
POLD1CDC2 | POLDpolymerase (DNA directed), delta 1, catalytic subunit 125kDaTwo-hybridBioGRID16169070 
PRAGMINDKFZp761P0423homolog of rat pragma of Rnd2Two-hybridBioGRID16169070 
PTEN10q23del | BZS | MGC11227 | MHAM | MMAC1 | PTEN1 | TEP1phosphatase and tensin homologTwo-hybridBioGRID16169070 
S100A860B8AG | CAGA | CFAG | CGLA | CP-10 | L1Ag | MA387 | MIF | MRP8 | NIF | P8S100 calcium binding protein A8Two-hybridBioGRID16169070 
SAFB2KIAA0138scaffold attachment factor B2Two-hybridBioGRID16169070 
SLC25A6AAC3 | ANT3 | ANT3Y | MGC17525solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6Two-hybridBioGRID16169070 
TAZBTHS | CMD3A | EFE | EFE2 | FLJ27390 | G4.5 | LVNCX | Taz1 | XAP-2tafazzinTwo-hybridBioGRID16169070 
TUBB2ATUBB | TUBB2 | dJ40E16.7tubulin, beta 2ATwo-hybridBioGRID16169070 
TWF2A6RP | A6r | MSTP011 | PTK9Ltwinfilin, actin-binding protein, homolog 2 (Drosophila)Two-hybridBioGRID16169070 
YLPM1C14orf170 | ZAP | ZAP3YLP motif containing 1Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP 276165All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_UP 341197All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN 291176All SZGR genes in this pathway
PROVENZANI_METASTASIS_UP 194112All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP 238135All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_UP 201127All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_F 5432All SZGR genes in this pathway
KIM_GERMINAL_CENTER_T_HELPER_UP 6642All SZGR genes in this pathway
RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_DN 3023All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
LEIN_NEURON_MARKERS 6945All SZGR genes in this pathway
LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES 3726All SZGR genes in this pathway
WANG_LSD1_TARGETS_DN 3930All SZGR genes in this pathway
OSADA_ASCL1_TARGETS_UP 4630All SZGR genes in this pathway
BRUECKNER_TARGETS_OF_MIRLET7A3_UP 11169All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
ROESSLER_LIVER_CANCER_METASTASIS_UP 10772All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-544941001Ahsa-miR-544AUUCUGCAUUUUUAGCAAGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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