Gene Page: PARP4

Summary
GeneID  143
Symbol  PARP4
Synonyms  ADPRTL1|PARPL|PH5P|VAULT3|VPARP|VWA5C|p193
Description  poly (ADP-ribose) polymerase family, member 4
See related  HGNC:271|MIM:607519|Ensembl:ENSG00000102699|HPRD:09598|
Locus tag  -
Gene type  protein-coding
Map location  13q11
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
KCNC20.820.76
RASSF50.810.84
ANKRD34C0.810.85
NPTX20.800.85
TRPM20.800.84
SSTR30.800.88
PTHLH0.800.84
GPR1230.800.78
ANXA60.800.86
SGPP20.790.82
Top 10 negatively co-expressed genes
RBMX2-0.44-0.63
FADS2-0.43-0.49
TUBB2B-0.43-0.59
TRAF4-0.43-0.61
RPL23A-0.43-0.60
GTF3C6-0.42-0.50
KIAA1949-0.42-0.48
CARHSP1-0.42-0.64
PDE9A-0.41-0.58
SEMA4B-0.41-0.48
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003950NAD+ ADP-ribosyltransferase activityNAS10644454 
GO:0003677DNA bindingTAS10100603 
GO:0016757transferase activity, transferring glycosyl groupsIEA-
GO:0019899enzyme bindingIDA15169895 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006464protein modification processTAS10100603 
GO:0006471protein amino acid ADP-ribosylationNAS10644454 
GO:0008219cell deathIMP12140175 
GO:0006281DNA repairNAS12101391 
GO:0006810transportNAS11855821 
GO:0006954inflammatory responseIMP12123754 
GO:0042493response to drugNAS11291045 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusNAS10644454 
GO:0005737cytoplasmIEA-
GO:0030529ribonucleoprotein complexNAS11479319 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MVPLRP | VAULT1major vault protein-HPRD,BioGRID10477748 |11855821 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_BASE_EXCISION_REPAIR 3522All SZGR genes in this pathway
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN 391222All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_UP 404246All SZGR genes in this pathway
JAERVINEN_AMPLIFIED_IN_LARYNGEAL_CANCER 4024All SZGR genes in this pathway
AIYAR_COBRA1_TARGETS_UP 3925All SZGR genes in this pathway
MEINHOLD_OVARIAN_CANCER_LOW_GRADE_UP 1915All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
SUNG_METASTASIS_STROMA_DN 5434All SZGR genes in this pathway
KAUFFMANN_DNA_REPAIR_GENES 230137All SZGR genes in this pathway
SHEPARD_BMYB_MORPHOLINO_UP 205126All SZGR genes in this pathway
DER_IFN_BETA_RESPONSE_UP 10267All SZGR genes in this pathway
FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN 4826All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_10HR_DN 5637All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
CUI_TCF21_TARGETS_DN 3123All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_DN 228146All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_DN 160101All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 307185All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN 258160All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP 298174All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_UP 518299All SZGR genes in this pathway
YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_DN 6531All SZGR genes in this pathway
WANG_METASTASIS_OF_BREAST_CANCER 158All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.