Gene Page: SEC14L2

Summary
GeneID  23541
Symbol  SEC14L2
Synonyms  C22orf6|KIAA1186|KIAA1658|MGC65053|SPF|TAP|TAP1
Description  SEC14-like 2 (S. cerevisiae)
See related  HGNC:10699|MIM:607558|Ensembl:ENSG00000100003|HPRD:06344|
Locus tag  -
Gene type  protein-coding
Map location  22q12.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ACTR1A0.920.91
RPN10.910.91
YWHAQ0.910.91
ARF40.910.91
CCT50.910.91
C7orf700.900.88
ATP5A10.900.88
MRPL30.900.90
NIPSNAP10.890.90
SLC25A170.890.89
Top 10 negatively co-expressed genes
MT-CO2-0.73-0.78
AF347015.8-0.72-0.78
AF347015.33-0.72-0.78
AF347015.27-0.70-0.77
AF347015.31-0.70-0.75
MT-CYB-0.70-0.75
AF347015.2-0.68-0.77
AF347015.21-0.68-0.77
AF347015.15-0.68-0.76
FXYD1-0.68-0.77
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005543phospholipid bindingNAS7364757 
GO:0005215transporter activityIEA-
GO:0008431vitamin E bindingNAS10829015 
GO:0016563transcription activator activityNAS11444841 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006350transcriptionIEA-
GO:0006810transportIEA-
GO:0045893positive regulation of transcription, DNA-dependentNAS11444841 
GO:0045540regulation of cholesterol biosynthetic processNAS11226224 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusNAS11444841 
GO:0005737cytoplasmNAS10829015 
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CALRCRT | FLJ26680 | RO | SSA | cC1qRcalreticulin-HPRD9036970 
PIK3CGPI3CG | PI3K | PI3Kgamma | PIK3phosphoinositide-3-kinase, catalytic, gamma polypeptide-HPRD12757856 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_DELTA_NP63_PATHWAY 4734All SZGR genes in this pathway
DOANE_RESPONSE_TO_ANDROGEN_UP 184125All SZGR genes in this pathway
LIU_LIVER_CANCER 3818All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_METASTASIS_UP 5631All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
SU_LIVER 5532All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_UP 388234All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
LEE_LIVER_CANCER_SURVIVAL_UP 185112All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_UP 16799All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN 238145All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G123_DN 5130All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP 176110All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN 17997All SZGR genes in this pathway
STEIN_ESRRA_TARGETS 535325All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP 229149All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_DN 242146All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP 211131All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
KRIEG_HYPOXIA_VIA_KDM3A 5334All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-125/3513593651Ahsa-miR-125bbrainUCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrainUCCCUGAGACCCUUUAACCUGUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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