Gene Page: LRP12

Summary
GeneID  29967
Symbol  LRP12
Synonyms  DKFZp781F1053|FLJ12929|ST7
Description  low density lipoprotein-related protein 12
See related  HGNC:31708|Ensembl:ENSG00000147650|HPRD:17447|
Locus tag  -
Gene type  protein-coding
Map location  8q22.2-q23.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.008 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005041low-density lipoprotein receptor activityNAS12809483 
GO:0004872receptor activityIEA-
GO:0005515protein bindingIPI12809483 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionNAS12809483 
GO:0006897endocytosisNAS12809483 
GO:0040008regulation of growthNAS9927190 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0005905coated pitIEA-
GO:0005887integral to plasma membraneIDA12809483 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTN2CMD1AAactinin, alpha 2-HPRD12809483 
GNB2L1Gnb2-rs1 | H12.3 | HLC-7 | PIG21 | RACK1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1-HPRD12809483 
ITGB1BP3MGC126624 | MIBP | NRK2integrin beta 1 binding protein 3-HPRD12809483 
MYOTLGMD1 | LGMD1A | TTIDmyotilin-HPRD12809483 
SNAPINSNAPAPSNAP-associated protein-HPRD12809483 
ZFYVE9MADHIP | NSP | SARA | SMADIPzinc finger, FYVE domain containing 9-HPRD12809483 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP 408247All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN 463290All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP 544308All SZGR genes in this pathway
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL 330215All SZGR genes in this pathway
XU_HGF_TARGETS_REPRESSED_BY_AKT1_UP 107All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_METASTASIS_DN 12165All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_MS_UP 4832All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
ULE_SPLICING_VIA_NOVA2 4338All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN 315197All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_DN 252155All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP 188121All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_UP 166105All SZGR genes in this pathway
LI_INDUCED_T_TO_NATURAL_KILLER_UP 307182All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-13737431Ahsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-142-5p7687751A,m8hsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-143706712m8hsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-153750756m8hsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-18113011307m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-221891951Ahsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
miR-37712631269m8hsa-miR-377AUCACACAAAGGCAACUUUUGU
miR-37813561362m8hsa-miR-378CUCCUGACUCCAGGUCCUGUGU
miR-493-5p4344411A,m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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