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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Gene Page: JAK2

Summary

GeneID

3717

Symbol

JAK2

Synonyms

JTK10

Description

Janus kinase 2 (a protein tyrosine kinase)

Locus tag

Gene type

protein-coding

Map location

9p24

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 4.0087

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

KIF3C

0.90

0.94

CEP68

0.89

0.92

INPP4A

0.89

0.92

CECR6

0.88

0.91

ATCAY

0.88

0.92

CAPN5

0.88

0.92

KLHL18

0.88

0.93

KIAA0317

0.88

0.93

DCLK1

0.88

0.91

MAPT

0.88

0.94

Top 10 negatively co-expressed genes

FXYD1

-0.70

-0.79

SERPINB6

-0.69

-0.75

AF347015.31

-0.68

-0.79

S100B

-0.68

-0.77

AC021016.1

-0.68

-0.79

HEPN1

-0.68

-0.71

MT-CO2

-0.68

-0.80

AF347015.33

-0.67

-0.76

COPZ2

-0.67

-0.74

TSC22D4

-0.67

-0.72

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005102

receptor binding

IPI

Neurotransmitter (GO term level: 4)

11201744

GO:0000166

nucleotide binding

IEA

GO:0005515

protein binding

IEA

GO:0005524

ATP binding

IEA

GO:0004718

Janus kinase activity

IEA

GO:0004713

protein tyrosine kinase activity

IEA

GO:0004715

non-membrane spanning protein tyrosine kinase activity

IEA

GO:0016740

transferase activity

IEA

GO:0042169

SH2 domain binding

IPI

9727029

GO:0016301

kinase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0030099

myeloid cell differentiation

IEA

GO:0007262

STAT protein nuclear translocation

IEA

GO:0007260

tyrosine phosphorylation of STAT protein

IEA

GO:0007167

enzyme linked receptor protein signaling pathway

IEA

GO:0008285

negative regulation of cell proliferation

IEA

GO:0007498

mesoderm development

TAS

9590174

GO:0006928

cell motion

TAS

9670957

GO:0006915

apoptosis

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0012505

endomembrane system

IEA

GO:0005856

cytoskeleton

IEA

GO:0016020

membrane

IEA

GO:0045121

membrane raft

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AGTR1	AG2S \| AGTR1A \| AGTR1B \| AT1 \| AT1B \| AT1R \| AT2R1 \| AT2R1A \| AT2R1B \| HAT1R	angiotensin II receptor, type 1	-	HPRD	7746328
BCR	ALL \| BCR-ABL1 \| BCR1 \| CML \| D22S11 \| D22S662 \| FLJ16453 \| PHL	breakpoint cluster region	-	HPRD,BioGRID	12023981 \|12370803
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	breast cancer 1, early onset	-	HPRD,BioGRID	11163768
CCR2	CC-CKR-2 \| CCR2A \| CCR2B \| CD192 \| CKR2 \| CKR2A \| CKR2B \| CMKBR2 \| MCP-1-R	chemokine (C-C motif) receptor 2	-	HPRD,BioGRID	9670957
CCR5	CC-CKR-5 \| CCCKR5 \| CD195 \| CKR-5 \| CKR5 \| CMKBR5	chemokine (C-C motif) receptor 5	-	HPRD	11591716
CCR5	CC-CKR-5 \| CCCKR5 \| CD195 \| CKR-5 \| CKR5 \| CMKBR5	chemokine (C-C motif) receptor 5	Affinity Capture-Western	BioGRID	11278738
CSF2RB	CD131 \| CDw131 \| IL3RB \| IL5RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	Affinity Capture-Western in vivo Reconstituted Complex	BioGRID	7527392 \|7775438 \|10772872
CSF3R	CD114 \| GCSFR	colony stimulating factor 3 receptor (granulocyte)	-	HPRD	7775438
CTLA4	CD152 \| CELIAC3 \| CTLA-4 \| GSE \| IDDM12	cytotoxic T-lymphocyte-associated protein 4	CTLA-4 interacts with Jak2.	BIND	10842319
CTLA4	CD152 \| CELIAC3 \| CTLA-4 \| GSE \| IDDM12	cytotoxic T-lymphocyte-associated protein 4	-	HPRD,BioGRID	10842319
CXCR4	CD184 \| D2S201E \| FB22 \| HM89 \| HSY3RR \| LAP3 \| LCR1 \| LESTR \| NPY3R \| NPYR \| NPYRL \| NPYY3R \| WHIM	chemokine (C-X-C motif) receptor 4	-	HPRD,BioGRID	10506573
DNAJA3	FLJ45758 \| TID1 \| hTid-1	DnaJ (Hsp40) homolog, subfamily A, member 3	-	HPRD,BioGRID	11679576
DNAJA3	FLJ45758 \| TID1 \| hTid-1	DnaJ (Hsp40) homolog, subfamily A, member 3	JAK2 interacts with Tid-1S.	BIND	11679576
EGFR	ERBB \| ERBB1 \| HER1 \| PIG61 \| mENA	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	Affinity Capture-Western	BioGRID	10358079
ELP2	FLJ10879 \| SHINC-2 \| STATIP1 \| StIP	elongation protein 2 homolog (S. cerevisiae)	-	HPRD,BioGRID	10954736
EPOR	MGC138358	erythropoietin receptor	-	HPRD,BioGRID	8343951 \|11779507
ERBB2	CD340 \| HER-2 \| HER-2/neu \| HER2 \| NEU \| NGL \| TKR1	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	-	HPRD,BioGRID	11940572
FYN	MGC45350 \| SLK \| SYN	FYN oncogene related to SRC, FGR, YES	-	HPRD,BioGRID	10551884
GHR	GHBP	growth hormone receptor	-	HPRD,BioGRID	7540178 \|8063815 \|10502458
GRB10	GRB-IR \| Grb-10 \| IRBP \| KIAA0207 \| MEG1 \| RSS	growth factor receptor-bound protein 10	-	HPRD,BioGRID	9632636
GRB2	ASH \| EGFRBP-GRB2 \| Grb3-3 \| MST084 \| MSTP084	growth factor receptor-bound protein 2	-	HPRD,BioGRID	7500025
HSPA8	HSC54 \| HSC70 \| HSC71 \| HSP71 \| HSP73 \| HSPA10 \| LAP1 \| MGC131511 \| MGC29929 \| NIP71	heat shock 70kDa protein 8	-	HPRD,BioGRID	11679576
HTR2A	5-HT2A \| HTR2	5-hydroxytryptamine (serotonin) receptor 2A	-	HPRD,BioGRID	9169451
IFNGR1	CD119 \| FLJ45734 \| IFNGR	interferon gamma receptor 1	Affinity Capture-Western	BioGRID	7673114
IFNGR2	AF-1 \| IFGR2 \| IFNGT1	interferon gamma receptor 2 (interferon gamma transducer 1)	-	HPRD	7514165
IFNGR2	AF-1 \| IFGR2 \| IFNGT1	interferon gamma receptor 2 (interferon gamma transducer 1)	Reconstituted Complex	BioGRID	7673114
IL12RB2	-	interleukin 12 receptor, beta 2	JAK2 interacts with IL12RB2.	BIND	9038232
IL12RB2	-	interleukin 12 receptor, beta 2	-	HPRD,BioGRID	10198225
IL23R	-	interleukin 23 receptor	-	HPRD	12023369
IL5RA	CD125 \| CDw125 \| HSIL5R3 \| IL5R \| MGC26560	interleukin 5 receptor, alpha	-	HPRD,BioGRID	9516124
IL6ST	CD130 \| CDw130 \| GP130 \| GP130-RAPS \| IL6R-beta	interleukin 6 signal transducer (gp130, oncostatin M receptor)	Affinity Capture-Western	BioGRID	9388212
IRS1	HIRS-1	insulin receptor substrate 1	Affinity Capture-Western Biochemical Activity	BioGRID	9492017 \|11208867
KIT	C-Kit \| CD117 \| PBT \| SCFR	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	-	HPRD,BioGRID	7527392 \|8611693 \|9355737
LEPR	CD295 \| OBR	leptin receptor	-	HPRD	8608603
LYN	FLJ26625 \| JTK8	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	-	HPRD,BioGRID	9573010
MDK	FLJ27379 \| MK \| NEGF2	midkine (neurite growth-promoting factor 2)	-	HPRD	9452495
OSMR	MGC150626 \| MGC150627 \| MGC75127 \| OSMRB	oncostatin M receptor	-	HPRD	10586060
PIK3R1	GRB1 \| p85 \| p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	-	HPRD,BioGRID	8702385
PPIA	CYPA \| CYPH \| MGC117158 \| MGC12404 \| MGC23397	peptidylprolyl isomerase A (cyclophilin A)	-	HPRD,BioGRID	12668872
PPP2R1B	MGC26454 \| PR65B	protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform	-	HPRD,BioGRID	11440634
PPP2R4	MGC2184 \| PP2A \| PR53 \| PTPA	protein phosphatase 2A activator, regulatory subunit 4	Affinity Capture-Western	BioGRID	8702385
PPP2R5A	B56A \| MGC131915 \| PR61A	protein phosphatase 2, regulatory subunit B', alpha isoform	-	HPRD	8702385
PRLR	hPRLrI	prolactin receptor	-	HPRD,BioGRID	10772872
PRMT5	HRMT1L5 \| IBP72 \| JBP1 \| SKB1 \| SKB1Hs	protein arginine methyltransferase 5	-	HPRD,BioGRID	10531356
PTK2	FADK \| FAK \| FAK1 \| pp125FAK	PTK2 protein tyrosine kinase 2	-	HPRD,BioGRID	9553131 \|10925297
PTK2B	CADTK \| CAKB \| FADK2 \| FAK2 \| FRNK \| PKB \| PTK \| PYK2 \| RAFTK	PTK2B protein tyrosine kinase 2 beta	-	HPRD,BioGRID	11818507
PTPN1	PTP1B	protein tyrosine phosphatase, non-receptor type 1	-	HPRD,BioGRID	11694501
PTPN11	BPTP3 \| CFC \| MGC14433 \| NS1 \| PTP-1D \| PTP2C \| SH-PTP2 \| SH-PTP3 \| SHP2	protein tyrosine phosphatase, non-receptor type 11	Biochemical Activity in vivo Reconstituted Complex	BioGRID	8639815 \|8912646 \|8995399
PTPN11		protein tyrosine phosphatase, non-receptor type 11	-	HPRD	7559603 \|8912646 \|8995399
PTPN12	PTP-PEST \| PTPG1	protein tyrosine phosphatase, non-receptor type 12	-	HPRD,BioGRID	11731619
PTPN6	HCP \| HCPH \| HPTP1C \| PTP-1C \| SH-PTP1 \| SHP-1 \| SHP-1L \| SHP1	protein tyrosine phosphatase, non-receptor type 6	-	HPRD,BioGRID	8943354
PTPRC	B220 \| CD45 \| CD45R \| GP180 \| LCA \| LY5 \| T200	protein tyrosine phosphatase, receptor type, C	-	HPRD	11201744
RAF1	CRAF \| NS5 \| Raf-1 \| c-Raf	v-raf-1 murine leukemia viral oncogene homolog 1	-	HPRD,BioGRID	8876196
SH2B1	DKFZp547G1110 \| FLJ30542 \| KIAA1299 \| SH2-B \| SH2B	SH2B adaptor protein 1	-	HPRD,BioGRID	9343427
SH2B1	DKFZp547G1110 \| FLJ30542 \| KIAA1299 \| SH2-B \| SH2B	SH2B adaptor protein 1	-	HPRD	10757801
SH2B2	APS	SH2B adaptor protein 2	Biochemical Activity	BioGRID	10374881
SH2B2	APS	SH2B adaptor protein 2	-	HPRD	10872802
SHC1	FLJ26504 \| SHC \| SHCA	SHC (Src homology 2 domain containing) transforming protein 1	-	HPRD,BioGRID	7535773 \|9126968
SIRPA	BIT \| CD172A \| MFR \| MYD-1 \| P84 \| PTPNS1 \| SHPS-1 \| SHPS1 \| SIRP \| SIRP-ALPHA-1 \| SIRPalpha \| SIRPalpha2	signal-regulatory protein alpha	-	HPRD,BioGRID	10842184
SOCS1	CIS1 \| CISH1 \| JAB \| SOCS-1 \| SSI-1 \| SSI1 \| TIP3	suppressor of cytokine signaling 1	-	HPRD	9202126 \|10064597 \|11971965
SOCS1	CIS1 \| CISH1 \| JAB \| SOCS-1 \| SSI-1 \| SSI1 \| TIP3	suppressor of cytokine signaling 1	Affinity Capture-Western in vitro in vivo Reconstituted Complex Two-hybrid	BioGRID	9202126 \|10064597 \|10455112 \|11713228 \|11971965
SOCS3	ATOD4 \| CIS3 \| Cish3 \| MGC71791 \| SOCS-3 \| SSI-3 \| SSI3	suppressor of cytokine signaling 3	-	HPRD,BioGRID	9344848 \|10421843
STAM	DKFZp686J2352 \| STAM1	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	-	HPRD,BioGRID	9133424
STAM2	DKFZp564C047 \| Hbp \| STAM2A \| STAM2B	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	-	HPRD,BioGRID	10899310
STAT3	APRF \| FLJ20882 \| HIES \| MGC16063	signal transducer and activator of transcription 3 (acute-phase response factor)	-	HPRD	10925297
STAT5A	MGF \| STAT5	signal transducer and activator of transcription 5A	-	HPRD,BioGRID	9575217
STAT5B	STAT5	signal transducer and activator of transcription 5B	Affinity Capture-Western Two-hybrid	BioGRID	9047382 \|9575217
TEC	MGC126760 \| MGC126762 \| PSCTK4	tec protein tyrosine kinase	-	HPRD,BioGRID	9473212
TNFRSF1A	CD120a \| FPF \| MGC19588 \| TBP1 \| TNF-R \| TNF-R-I \| TNF-R55 \| TNFAR \| TNFR1 \| TNFR55 \| TNFR60 \| p55 \| p55-R \| p60	tumor necrosis factor receptor superfamily, member 1A	-	HPRD,BioGRID	9510175
TSHR	CHNG1 \| LGR3 \| MGC75129 \| hTSHR-I	thyroid stimulating hormone receptor	-	HPRD,BioGRID	10809230
TUB	rd5	tubby homolog (mouse)	-	HPRD,BioGRID	10455176
UBASH3B	KIAA1959 \| MGC15437 \| STS-1 \| STS1 \| p70	ubiquitin associated and SH3 domain containing, B	-	HPRD	12370296
VAV1	VAV	vav 1 guanine nucleotide exchange factor	-	HPRD,BioGRID	7530656 \|9162069
VCP	IBMPFD \| MGC131997 \| MGC148092 \| MGC8560 \| TERA \| p97	valosin-containing protein	-	HPRD,BioGRID	11087817
YES1	HsT441 \| P61-YES \| Yes \| c-yes	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	-	HPRD,BioGRID	8702385

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_CHEMOKINE_SIGNALING_PATHWAY	190	128	All SZGR genes in this pathway
KEGG_JAK_STAT_SIGNALING_PATHWAY	155	105	All SZGR genes in this pathway
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY	67	57	All SZGR genes in this pathway
KEGG_LEISHMANIA_INFECTION	72	56	All SZGR genes in this pathway
BIOCARTA_BIOPEPTIDES_PATHWAY	45	35	All SZGR genes in this pathway
BIOCARTA_TID_PATHWAY	19	15	All SZGR genes in this pathway
BIOCARTA_EPO_PATHWAY	19	13	All SZGR genes in this pathway
BIOCARTA_EPONFKB_PATHWAY	11	11	All SZGR genes in this pathway
BIOCARTA_GH_PATHWAY	28	22	All SZGR genes in this pathway
BIOCARTA_IL3_PATHWAY	15	11	All SZGR genes in this pathway
BIOCARTA_IL6_PATHWAY	22	16	All SZGR genes in this pathway
BIOCARTA_IL12_PATHWAY	23	17	All SZGR genes in this pathway
BIOCARTA_IL22BP_PATHWAY	16	12	All SZGR genes in this pathway
BIOCARTA_GLEEVEC_PATHWAY	23	17	All SZGR genes in this pathway
BIOCARTA_NO2IL12_PATHWAY	17	14	All SZGR genes in this pathway
BIOCARTA_TPO_PATHWAY	24	17	All SZGR genes in this pathway
ST_INTERFERON_GAMMA_PATHWAY	10	7	All SZGR genes in this pathway
ST_JAK_STAT_PATHWAY	9	8	All SZGR genes in this pathway
ST_STAT3_PATHWAY	11	10	All SZGR genes in this pathway
ST_INTERLEUKIN_4_PATHWAY	26	18	All SZGR genes in this pathway
PID_ENDOTHELIN_PATHWAY	63	52	All SZGR genes in this pathway
PID_ERBB4_PATHWAY	38	32	All SZGR genes in this pathway
PID_GMCSF_PATHWAY	37	31	All SZGR genes in this pathway
PID_IL4_2PATHWAY	65	43	All SZGR genes in this pathway
PID_IL27_PATHWAY	26	20	All SZGR genes in this pathway
PID_PTP1B_PATHWAY	52	40	All SZGR genes in this pathway
PID_IL12_2PATHWAY	63	54	All SZGR genes in this pathway
PID_S1P_S1P3_PATHWAY	29	24	All SZGR genes in this pathway
PID_SHP2_PATHWAY	58	46	All SZGR genes in this pathway
PID_CXCR4_PATHWAY	102	78	All SZGR genes in this pathway
PID_IL5_PATHWAY	14	11	All SZGR genes in this pathway
PID_IFNG_PATHWAY	40	34	All SZGR genes in this pathway
PID_ERBB2_ERBB3_PATHWAY	44	35	All SZGR genes in this pathway
PID_IL3_PATHWAY	27	19	All SZGR genes in this pathway
PID_IL6_7_PATHWAY	47	40	All SZGR genes in this pathway
PID_PDGFRB_PATHWAY	129	103	All SZGR genes in this pathway
PID_IL23_PATHWAY	37	30	All SZGR genes in this pathway
PID_KIT_PATHWAY	52	40	All SZGR genes in this pathway
PID_EPO_PATHWAY	34	29	All SZGR genes in this pathway
PID_HES_HEY_PATHWAY	48	39	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_SCF_KIT	78	59	All SZGR genes in this pathway
REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING	24	19	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB4	90	67	All SZGR genes in this pathway
REACTOME_PROLACTIN_RECEPTOR_SIGNALING	14	11	All SZGR genes in this pathway
REACTOME_NUCLEAR_SIGNALING_BY_ERBB4	38	30	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ILS	107	86	All SZGR genes in this pathway
REACTOME_IL_3_5_AND_GM_CSF_SIGNALING	43	34	All SZGR genes in this pathway
REACTOME_IL_RECEPTOR_SHC_SIGNALING	27	21	All SZGR genes in this pathway
REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	132	101	All SZGR genes in this pathway
REACTOME_REGULATION_OF_IFNG_SIGNALING	14	10	All SZGR genes in this pathway
REACTOME_INTERFERON_GAMMA_SIGNALING	63	48	All SZGR genes in this pathway
REACTOME_INTERFERON_SIGNALING	159	116	All SZGR genes in this pathway
REACTOME_IL_2_SIGNALING	41	34	All SZGR genes in this pathway
REACTOME_IL_6_SIGNALING	11	9	All SZGR genes in this pathway
REACTOME_HEMOSTASIS	466	331	All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM	933	616	All SZGR genes in this pathway
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM	270	204	All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP	567	375	All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP	423	283	All SZGR genes in this pathway
ELVIDGE_HYPOXIA_DN	146	94	All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_DN	59	40	All SZGR genes in this pathway
ELVIDGE_HIF1A_TARGETS_UP	67	40	All SZGR genes in this pathway
ELVIDGE_HIF2A_TARGETS_UP	6	5	All SZGR genes in this pathway
TSAI_RESPONSE_TO_IONIZING_RADIATION	149	101	All SZGR genes in this pathway
PUJANA_BREAST_CANCER_LIT_INT_NETWORK	101	73	All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK	1442	892	All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP	1037	673	All SZGR genes in this pathway
BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_UP	25	17	All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_3	28	23	All SZGR genes in this pathway
MORI_MATURE_B_LYMPHOCYTE_UP	90	62	All SZGR genes in this pathway
TENEDINI_MEGAKARYOCYTE_MARKERS	66	48	All SZGR genes in this pathway
OKUMURA_INFLAMMATORY_RESPONSE_LPS	183	115	All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN	366	238	All SZGR genes in this pathway
FAELT_B_CLL_WITH_VH_REARRANGEMENTS_UP	48	34	All SZGR genes in this pathway
HALMOS_CEBPA_TARGETS_UP	52	34	All SZGR genes in this pathway
JAIN_NFKB_SIGNALING	75	44	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN	1237	837	All SZGR genes in this pathway
JACKSON_DNMT1_TARGETS_UP	77	57	All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4	307	185	All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_T7	98	63	All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED	1022	619	All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED	1229	713	All SZGR genes in this pathway
MARSON_FOXP3_TARGETS_STIMULATED_UP	29	19	All SZGR genes in this pathway
MARSON_FOXP3_CORE_DIRECT_TARGETS	19	14	All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN	409	268	All SZGR genes in this pathway
MARZEC_IL2_SIGNALING_DN	36	24	All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP	323	240	All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP	1305	895	All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN	366	257	All SZGR genes in this pathway
HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP	43	34	All SZGR genes in this pathway
MIKKELSEN_PLURIPOTENT_STATE_DN	8	7	All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_UP	181	106	All SZGR genes in this pathway
MARSON_FOXP3_TARGETS_DN	54	38	All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_DN	222	141	All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP	229	149	All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP	324	193	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE	1137	655	All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP	745	475	All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP	682	433	All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	1080	713	All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_2HR_DN	55	35	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-135	935	942	1A,m8	hsa-miR-135a	UAUGGCUUUUUAUUCCUAUGUGA
miR-135	935	942	1A,m8	hsa-miR-135b	UAUGGCUUUUCAUUCCUAUGUG
miR-216	833	840	1A,m8	hsa-miR-216	UAAUCUCAGCUGGCAACUGUG
miR-375	636	642	1A	hsa-miR-375	UUUGUUCGUUCGGCUCGCGUGA
miR-381	656	662	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-433-3p	101	107	m8	hsa-miR-433^brain	AUCAUGAUGGGCUCCUCGGUGU
miR-496	325	331	1A	hsa-miR-496	AUUACAUGGCCAAUCUC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.