Gene Page: ARL1

Summary
GeneID  400
Symbol  ARL1
Synonyms  ARFL1
Description  ADP-ribosylation factor-like 1
See related  HGNC:692|MIM:603425|Ensembl:ENSG00000120805|HPRD:04574|
Locus tag  -
Gene type  protein-coding
Map location  12q23.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0032 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PSMA20.910.89
TBCA0.910.89
RBM340.910.89
ERH0.900.91
TMSB100.890.91
SARNP0.890.88
GLRX30.890.91
DPY300.880.87
POLB0.880.88
DPH50.880.89
Top 10 negatively co-expressed genes
AF347015.2-0.64-0.74
AF347015.15-0.63-0.73
AF347015.26-0.63-0.73
AF347015.33-0.63-0.71
MT-CYB-0.63-0.71
AF347015.8-0.62-0.70
AF347015.27-0.62-0.70
MT-CO2-0.61-0.67
TINAGL1-0.60-0.69
SLC6A12-0.60-0.69
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003924GTPase activityTAS9624189 
GO:0005515protein bindingIPI17353931 
GO:0005525GTP bindingIEA-
GO:0008047enzyme activator activityTAS9624189 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007264small GTPase mediated signal transductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIDA11256614 
GO:0005622intracellularIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARFIP2POR1ADP-ribosylation factor interacting protein 2Two-hybridBioGRID12972563 
CDK5RAP3C53 | HSF-27 | IC53 | LZAP | MST016 | OK/SW-cl.114CDK5 regulatory subunit associated protein 3Affinity Capture-MSBioGRID17353931 
GCC1FLJ22035 | GCC1P | GCC88 | MGC20706GRIP and coiled-coil domain containing 1Two-hybridBioGRID12972563 
GCC2GCC185 | KIAA0336GRIP and coiled-coil domain containing 2Two-hybridBioGRID12972563 
GOLGA1MGC33154 | golgin-97golgi autoantigen, golgin subfamily a, 1-HPRD,BioGRID12972563 
GOLGA4GCP2 | GOLG | MU-RMS-40.18 | p230golgi autoantigen, golgin subfamily a, 4-HPRD,BioGRID11303027 |12972563 
SCOCHRIHFB2072 | SCOCOshort coiled-coil protein-HPRD11303027 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
NAM_FXYD5_TARGETS_DN 1811All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_DN 6642All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_UP 305185All SZGR genes in this pathway
BARRIER_COLON_CANCER_RECURRENCE_UP 4228All SZGR genes in this pathway
CHOW_RASSF1_TARGETS_DN 2919All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_DN 314188All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_UP 2512All SZGR genes in this pathway
HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP 163102All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP 11573All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4962032091Ahsa-miR-496AUUACAUGGCCAAUCUC
miR-94054111Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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