Gene Page: NFKBIA

Summary
GeneID  4792
Symbol  NFKBIA
Synonyms  IKBA|MAD-3|NFKBI
Description  nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
See related  HGNC:7797|MIM:164008|Ensembl:ENSG00000100906|HPRD:01235|
Locus tag  -
Gene type  protein-coding
Map location  14q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.1501 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008139nuclear localization sequence bindingIPI1493333 
GO:0031625ubiquitin protein ligase bindingIPI9859996 
GO:0051059NF-kappaB bindingIPI7739562 
GO:0042802identical protein bindingIPI16951195 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000060protein import into nucleus, translocationIEA-
GO:0007253cytoplasmic sequestering of NF-kappaBNAS-
GO:0006915apoptosisTAS10747850 
GO:0042345regulation of NF-kappaB import into nucleusNAS3140380 
GO:0042127regulation of cell proliferationIEA-
GO:0032496response to lipopolysaccharideIEA-
GO:0031663lipopolysaccharide-mediated signaling pathwayIEA-
GO:0043392negative regulation of DNA bindingNAS3140380 
GO:0043330response to exogenous dsRNAIEA-
GO:0032495response to muramyl dipeptideIEA-
GO:0045638negative regulation of myeloid cell differentiationIEA-
GO:0045746negative regulation of Notch signaling pathwayIEA-
GO:0044419interspecies interaction between organismsIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP10723127 
GO:0005829cytosolIEA-
GO:0005634nucleusIDA7679069 
GO:0005737cytoplasmIDA3140380 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARRB1ARB1 | ARR1arrestin, beta 1Beta-Arr1 interacts with I-kappa-B-alpha to prevent the phosphorylation and degradation of I-kappa-B-alpha.BIND15125834 
ARRB2ARB2 | ARR2 | BARR2 | DKFZp686L0365arrestin, beta 2The amino terminus of Beta-Arr2 interacts with the carboxy terminus of I-kappa-B-alpha to prevent I-kappa-B-alpha phosphorylation and degradation.BIND15125834 
BARD1-BRCA1 associated RING domain 1Two-hybridBioGRID10362352 
BTRCBETA-TRCP | FBW1A | FBXW1 | FBXW1A | FWD1 | MGC4643 | bTrCP | bTrCP1 | betaTrCPbeta-transducin repeat containing-HPRD,BioGRID9990853 
h-beta-TrCP interacts with and promotes ubiquitination of phosphorylated I-kappa-B-alpha. This interaction was modeled on a demonstrated interaction between human beta-TrCP (h-beta-TrCP) and I-kappa-B-alpha from an unspecified species.BIND9990853 
CAPN1CANP | CANP1 | CANPL1 | muCANP | muCLcalpain 1, (mu/I) large subunit-HPRD,BioGRID10521480 
CHUKIKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16conserved helix-loop-helix ubiquitous kinaseBiochemical Activity
Reconstituted Complex
BioGRID9252186 |9751059 
IKK-alpha phosphorylates I-kappa-B-alpha.BIND9346485 
Ikk-alpha phosphorylates I-kappa-B-alpha. This interaction was modeled on a demonstrated interaction between human IKK-alpha and I-kappa-B-alpha from an unspecified species.BIND15782119 
COMMD1C2orf5 | MGC27155 | MURR1copper metabolism (Murr1) domain containing 1Affinity Capture-WesternBioGRID14685242 
Murr1 interacts with I-kappaB-alphaBIND14685242 
DYNLL1DLC1 | DLC8 | DNCL1 | DNCLC1 | LC8 | LC8a | MGC126137 | MGC126138 | PIN | hdlc1dynein, light chain, LC8-type 1-HPRD,BioGRID9372968 
I-kappa-B-alpha interacts with Dlc-1.BIND9372968 
ELP3FLJ10422 | KAT9elongation protein 3 homolog (S. cerevisiae)-HPRD14743216 
ERC1Cast2 | ELKS | KIAA1081 | MGC12974 | RAB6IP2ELKS/RAB6-interacting/CAST family member 1ELKS interacts with I-kappa-B-alpha.BIND15218148 
FBXW11BTRC2 | BTRCP2 | FBW1B | FBXW1B | Fbw11 | Hos | KIAA0696F-box and WD repeat domain containing 11-HPRD,BioGRID10644755 
G3BP2-GTPase activating protein (SH3 domain) binding protein 2-HPRD,BioGRID10969074 
HDAC1DKFZp686H12203 | GON-10 | HD1 | RPD3 | RPD3L1histone deacetylase 1HDAC1 interacts with I-kappa-B-alpha.BIND12972430 
HDAC3HD3 | RPD3 | RPD3-2histone deacetylase 3HDAC3 interacts with I-kappa-B-alpha.BIND12972430 
HNRNPA1HNRPA1 | MGC102835heterogeneous nuclear ribonucleoprotein A1Affinity Capture-Western
Reconstituted Complex
BioGRID11313474 
HNRNPABABBP1 | FLJ40338 | HNRPABheterogeneous nuclear ribonucleoprotein A/B-HPRD11313474 
HOXB7HHO.C1 | HOX2 | HOX2C | Hox-2.3homeobox B7-HPRD,BioGRID10026139 
HSPA8HSC54 | HSC70 | HSC71 | HSP71 | HSP73 | HSPA10 | LAP1 | MGC131511 | MGC29929 | NIP71heat shock 70kDa protein 8-HPRD14743216 
IKBKAPDKFZp781H1425 | DYS | ELP1 | FD | FLJ12497 | IKAP | IKI3 | TOT1inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated proteinReconstituted ComplexBioGRID9751059 
IKBKBFLJ40509 | IKK-beta | IKK2 | IKKB | MGC131801 | NFKBIKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase betaIKK-beta interacts with and phosphorylates I-kappa-B-alpha.BIND9346485 
IKK-beta interacts with and phosphorylates I-kappa-B-alpha. This interaction was modelled on a demonstrated interaction between IKK-beta and I-kappa-B-alpha both from unspecified species.BIND15808510 
Reconstituted ComplexBioGRID9751059 |9891086 
IKK-beta phosphorylates I-kappa-Ba. This interaction was modelled on a demonstrated interaction between IKK-beta from unknown species and I-kappa-Ba from unknown species.BIND15084260 
LCKYT16 | p56lck | pp58lcklymphocyte-specific protein tyrosine kinaseLCK interacts with and phosphorylates NFKBIA (I-kappa-B-alpha). This interaction was modeled on a demonstrated interaction between LCK from an unspecified species and human NFKBIA.BIND14534291 
MAP3K14FTDCR1B | HS | HSNIK | NIKmitogen-activated protein kinase kinase kinase 14Reconstituted ComplexBioGRID9751059 
MCM7CDABP0042 | CDC47 | MCM2 | P1.1-MCM3 | P1CDC47 | P85MCM | PNAS-146minichromosome maintenance complex component 7-HPRD14743216 
MED19DT2P1G7 | LCMR1mediator complex subunit 19Two-hybridBioGRID16169070 
NCOR2CTG26 | SMRT | SMRTE | SMRTE-tau | TNRC14 | TRAC-1 | TRAC1nuclear receptor co-repressor 2Affinity Capture-WesternBioGRID12589049 
NFKB1DKFZp686C01211 | EBP-1 | KBF1 | MGC54151 | NF-kappa-B | NFKB-p105 | NFKB-p50 | p105nuclear factor of kappa light polypeptide gene enhancer in B-cells 1-HPRD,BioGRID9738011 
p50 associates with I-kappa-B-alpha.BIND9135156 
PIK3R1GRB1 | p85 | p85-ALPHAphosphoinositide-3-kinase, regulatory subunit 1 (alpha)-HPRD,BioGRID9892650 
PIR-pirin (iron-binding nuclear protein)Two-hybridBioGRID10362352 
POM121DKFZp586G1822 | DKFZp586P2220 | FLJ41820 | KIAA0618 | MGC3792 | POM121APOM121 membrane glycoprotein (rat)Two-hybridBioGRID16189514 
PTPN13DKFZp686J1497 | FAP-1 | PNP1 | PTP-BAS | PTP-BL | PTP1E | PTPL1 | PTPLEprotein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)-HPRD,BioGRID9882613 
RELC-Relv-rel reticuloendotheliosis viral oncogene homolog (avian)Affinity Capture-WesternBioGRID10706725 
RELAMGC131774 | NFKB3 | p65v-rel reticuloendotheliosis viral oncogene homolog A (avian)Affinity Capture-Western
Reconstituted Complex
BioGRID8139561 |9738011 
|9751059 |9990853 
|11313474 |11533489 
|12419806 
I-kappa-B-alpha interacts with NF-kappa-B-p65.BIND15125834 
RelA, the p65 subunit of the NF-kappaB complex, interacts with I-kappaB-alphaBIND14685242 
RPS27L-ribosomal protein S27-like-HPRD14743216 
RPS6KA1HU-1 | MAPKAPK1A | RSK | RSK1ribosomal protein S6 kinase, 90kDa, polypeptide 1-HPRD,BioGRID9214631 
SUMO4IDDM5 | SMT3H4 | SUMO-4 | dJ281H8.4SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)-HPRD,BioGRID15247916 
TIMM50MGC102733 | TIM50 | TIM50Ltranslocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)-HPRD14743216 
TNFSF11CD254 | ODF | OPGL | OPTB2 | RANKL | TRANCE | hRANKL2 | sOdftumor necrosis factor (ligand) superfamily, member 11-HPRD10635328 
TP53FLJ92943 | LFS1 | TRP53 | p53tumor protein p53-HPRD,BioGRID11799106 
TUBA1BK-ALPHA-1tubulin, alpha 1b-HPRD9372968 
TUBA3CTUBA2 | bA408E5.3tubulin, alpha 3c-HPRD9372968 
UBE2E3UBCH9 | UbcM2ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)-HPRD,BioGRID9409737 
VCPIBMPFD | MGC131997 | MGC148092 | MGC8560 | TERA | p97valosin-containing protein-HPRD,BioGRID9452483 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CHEMOKINE_SIGNALING_PATHWAY 190128All SZGR genes in this pathway
KEGG_APOPTOSIS 8862All SZGR genes in this pathway
KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 10288All SZGR genes in this pathway
KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY 6247All SZGR genes in this pathway
KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 7151All SZGR genes in this pathway
KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY 5644All SZGR genes in this pathway
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 10889All SZGR genes in this pathway
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 7556All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 126103All SZGR genes in this pathway
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 6757All SZGR genes in this pathway
KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION 6844All SZGR genes in this pathway
KEGG_LEISHMANIA_INFECTION 7256All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_PROSTATE_CANCER 8975All SZGR genes in this pathway
KEGG_CHRONIC_MYELOID_LEUKEMIA 7359All SZGR genes in this pathway
KEGG_SMALL_CELL_LUNG_CANCER 8467All SZGR genes in this pathway
BIOCARTA_RELA_PATHWAY 1612All SZGR genes in this pathway
BIOCARTA_AKT_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_ATM_PATHWAY 2016All SZGR genes in this pathway
BIOCARTA_CDMAC_PATHWAY 1615All SZGR genes in this pathway
BIOCARTA_CD40_PATHWAY 1513All SZGR genes in this pathway
BIOCARTA_TID_PATHWAY 1915All SZGR genes in this pathway
BIOCARTA_RNA_PATHWAY 109All SZGR genes in this pathway
BIOCARTA_EPONFKB_PATHWAY 1111All SZGR genes in this pathway
BIOCARTA_FMLP_PATHWAY 3929All SZGR genes in this pathway
BIOCARTA_HIVNEF_PATHWAY 5843All SZGR genes in this pathway
BIOCARTA_DEATH_PATHWAY 3324All SZGR genes in this pathway
BIOCARTA_RACCYCD_PATHWAY 2623All SZGR genes in this pathway
BIOCARTA_KERATINOCYTE_PATHWAY 4638All SZGR genes in this pathway
BIOCARTA_MAPK_PATHWAY 8768All SZGR genes in this pathway
BIOCARTA_PPARA_PATHWAY 5843All SZGR genes in this pathway
BIOCARTA_VIP_PATHWAY 2926All SZGR genes in this pathway
BIOCARTA_NTHI_PATHWAY 2420All SZGR genes in this pathway
BIOCARTA_NFKB_PATHWAY 2319All SZGR genes in this pathway
BIOCARTA_IL1R_PATHWAY 3329All SZGR genes in this pathway
BIOCARTA_TCR_PATHWAY 4937All SZGR genes in this pathway
BIOCARTA_41BB_PATHWAY 1715All SZGR genes in this pathway
BIOCARTA_STRESS_PATHWAY 2518All SZGR genes in this pathway
BIOCARTA_TNFR2_PATHWAY 1815All SZGR genes in this pathway
BIOCARTA_TOLL_PATHWAY 3731All SZGR genes in this pathway
ST_TUMOR_NECROSIS_FACTOR_PATHWAY 2920All SZGR genes in this pathway
SIG_CD40PATHWAYMAP 3428All SZGR genes in this pathway
ST_GAQ_PATHWAY 2822All SZGR genes in this pathway
ST_GA13_PATHWAY 3732All SZGR genes in this pathway
ST_T_CELL_SIGNAL_TRANSDUCTION 4533All SZGR genes in this pathway
ST_B_CELL_ANTIGEN_RECEPTOR 4032All SZGR genes in this pathway
ST_FAS_SIGNALING_PATHWAY 6554All SZGR genes in this pathway
PID_BCR_5PATHWAY 6550All SZGR genes in this pathway
PID_LYSOPHOSPHOLIPID_PATHWAY 6653All SZGR genes in this pathway
PID_NFKAPPAB_ATYPICAL_PATHWAY 1715All SZGR genes in this pathway
PID_NFKAPPAB_CANONICAL_PATHWAY 2320All SZGR genes in this pathway
PID_CD40_PATHWAY 3126All SZGR genes in this pathway
PID_AVB3_OPN_PATHWAY 3129All SZGR genes in this pathway
PID_HDAC_CLASSI_PATHWAY 6650All SZGR genes in this pathway
PID_CERAMIDE_PATHWAY 4837All SZGR genes in this pathway
PID_IL23_PATHWAY 3730All SZGR genes in this pathway
PID_HIV_NEF_PATHWAY 3526All SZGR genes in this pathway
PID_AURORA_A_PATHWAY 3120All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_TRIF_MEDIATED_TLR3_SIGNALING 7454All SZGR genes in this pathway
REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI 1815All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 9766All SZGR genes in this pathway
REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS 6443All SZGR genes in this pathway
REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 12690All SZGR genes in this pathway
REACTOME_TCR_SIGNALING 5446All SZGR genes in this pathway
REACTOME_DOWNSTREAM_TCR_SIGNALING 3732All SZGR genes in this pathway
REACTOME_P75NTR_SIGNALS_VIA_NFKB 1410All SZGR genes in this pathway
REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL 118All SZGR genes in this pathway
REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 8161All SZGR genes in this pathway
REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX 2317All SZGR genes in this pathway
REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION 2117All SZGR genes in this pathway
REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION 7757All SZGR genes in this pathway
REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE 7253All SZGR genes in this pathway
REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS 7357All SZGR genes in this pathway
REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE 8363All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM 279178All SZGR genes in this pathway
REACTOME_ACTIVATED_TLR4_SIGNALLING 9369All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_TOLL_RECEPTOR_CASCADES 11884All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM 539350All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP 294178All SZGR genes in this pathway
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP 485293All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP 177110All SZGR genes in this pathway
BASAKI_YBX1_TARGETS_UP 290177All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP 233161All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_UP 457269All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
HUMMEL_BURKITTS_LYMPHOMA_DN 1510All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP 544308All SZGR genes in this pathway
KIM_WT1_TARGETS_UP 214155All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN 805505All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP 12895All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN 7550All SZGR genes in this pathway
LAU_APOPTOSIS_CDKN2A_UP 5540All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP 12672All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_UP 2920All SZGR genes in this pathway
OLSSON_E2F3_TARGETS_DN 4933All SZGR genes in this pathway
GILMORE_CORE_NFKB_PATHWAY 1410All SZGR genes in this pathway
SCHEIDEREIT_IKK_TARGETS 1815All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_2 12792All SZGR genes in this pathway
RASHI_NFKB1_TARGETS 1918All SZGR genes in this pathway
MARTIN_INTERACT_WITH_HDAC 4431All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
DIRMEIER_LMP1_RESPONSE_EARLY 6648All SZGR genes in this pathway
TSAI_RESPONSE_TO_IONIZING_RADIATION 149101All SZGR genes in this pathway
PUJANA_BREAST_CANCER_LIT_INT_NETWORK 10173All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_DN 156106All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_HIF1A_DN 11078All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP 142104All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER 214139All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_DN 411249All SZGR genes in this pathway
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN 206136All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_8 3628All SZGR genes in this pathway
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP 223140All SZGR genes in this pathway
ZUCCHI_METASTASIS_DN 4429All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
YAGI_AML_RELAPSE_PROGNOSIS 3524All SZGR genes in this pathway
GOLUB_ALL_VS_AML_DN 2414All SZGR genes in this pathway
SANA_TNF_SIGNALING_UP 8356All SZGR genes in this pathway
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN 8567All SZGR genes in this pathway
NEMETH_INFLAMMATORY_RESPONSE_LPS_UP 8864All SZGR genes in this pathway
LENAOUR_DENDRITIC_CELL_MATURATION_DN 12890All SZGR genes in this pathway
VERHAAK_AML_WITH_NPM1_MUTATED_UP 183111All SZGR genes in this pathway
YAGI_AML_SURVIVAL 12987All SZGR genes in this pathway
IGLESIAS_E2F_TARGETS_UP 151103All SZGR genes in this pathway
MUNSHI_MULTIPLE_MYELOMA_UP 8152All SZGR genes in this pathway
BASSO_CD40_SIGNALING_UP 10176All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP 314201All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_NEOCORTEX_UP 8366All SZGR genes in this pathway
HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_4HR 3722All SZGR genes in this pathway
ZHOU_TNF_SIGNALING_4HR 5436All SZGR genes in this pathway
MCDOWELL_ACUTE_LUNG_INJURY_UP 4529All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
NATSUME_RESPONSE_TO_INTERFERON_BETA_DN 5233All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL 254164All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP 10369All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
ZHU_CMV_ALL_UP 12089All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_UP 178111All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C0 10772All SZGR genes in this pathway
ZHOU_TNF_SIGNALING_30MIN 5436All SZGR genes in this pathway
GEISS_RESPONSE_TO_DSRNA_UP 3829All SZGR genes in this pathway
ZHU_CMV_24_HR_UP 9365All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_24HR_UP 14896All SZGR genes in this pathway
HILLION_HMGA1_TARGETS 9071All SZGR genes in this pathway
HILLION_HMGA1B_TARGETS 9268All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN 154101All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP 439257All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
CHEN_HOXA5_TARGETS_9HR_UP 223132All SZGR genes in this pathway
QI_PLASMACYTOMA_UP 259185All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_UP 245159All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_UP 374247All SZGR genes in this pathway
VILIMAS_NOTCH1_TARGETS_UP 5241All SZGR genes in this pathway
SEKI_INFLAMMATORY_RESPONSE_LPS_UP 7756All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP 10767All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_B 5336All SZGR genes in this pathway
MARSHALL_VIRAL_INFECTION_RESPONSE_DN 2921All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
HINATA_NFKB_TARGETS_KERATINOCYTE_UP 9163All SZGR genes in this pathway
HINATA_NFKB_TARGETS_FIBROBLAST_UP 8460All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 196124All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES 389245All SZGR genes in this pathway
CROONQUIST_STROMAL_STIMULATION_UP 6042All SZGR genes in this pathway
CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN 9965All SZGR genes in this pathway
COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN 13899All SZGR genes in this pathway
SCHOEN_NFKB_SIGNALING 3426All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S3 266180All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_DN 210141All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_12HR_DN 3325All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_24HR_DN 4332All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_32HR_DN 3928All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_48HR_DN 4029All SZGR genes in this pathway
TIAN_TNF_SIGNALING_VIA_NFKB 2821All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_3 157All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_2HR_UP 3930All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
WANG_TNF_TARGETS 2417All SZGR genes in this pathway
KASLER_HDAC7_TARGETS_2_DN 3223All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
PHONG_TNF_TARGETS_UP 6343All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION 12881All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-38127341A,m8hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-493-5p37431Ahsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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