Gene Page: NRCAM

Summary
GeneID  4897
Symbol  NRCAM
Synonyms  KIAA0343|MGC138845|MGC138846
Description  neuronal cell adhesion molecule
See related  HGNC:7994|MIM:601581|Ensembl:ENSG00000091129|HPRD:07207|
Locus tag  -
Gene type  protein-coding
Map location  7q31.1-q31.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 8 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CNOT10.960.96
C2CD30.940.95
KDM3B0.940.95
IPO90.940.94
PRPF80.940.96
DHX80.940.96
CRKRS0.940.95
SNRNP2000.940.94
LIG30.940.95
MSL20.940.96
Top 10 negatively co-expressed genes
AF347015.31-0.75-0.85
MT-CO2-0.74-0.85
IFI27-0.72-0.82
AF347015.21-0.72-0.89
AF347015.27-0.71-0.82
FXYD1-0.71-0.82
AF347015.8-0.70-0.83
AF347015.33-0.70-0.79
HIGD1B-0.69-0.82
MT-CYB-0.69-0.80
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingNAS11483367 
GO:0030506ankyrin bindingIDA14602817 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0045162clustering of voltage-gated sodium channelsIDAneuron, axon (GO term level: 12)14602817 
GO:0007417central nervous system developmentNASBrain (GO term level: 6)8812479 
GO:0007416synaptogenesisTASSynap (GO term level: 6)8812479 
GO:0007413axonal fasciculationNASneuron, axon (GO term level: 13)8812479 
GO:0001764neuron migrationNASneuron (GO term level: 8)11483367 
GO:0030516regulation of axon extensionNASaxon (GO term level: 14)8812479 
GO:0045666positive regulation of neuron differentiationNASneuron (GO term level: 10)8812479 
GO:0016337cell-cell adhesionNAS8812479 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0043005neuron projectionNASneuron, axon, neurite, dendrite (GO term level: 5)8812479 
GO:0009897external side of plasma membraneNAS8812479 
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneNAS8812479 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ANK2DKFZp686M09125 | DKFZp686P0948 | FLJ38277 | LQT4ankyrin 2, neuronal-HPRD11449000 
CNTN2AXT | DKFZp781D102 | FLJ42746 | MGC157722 | TAG-1 | TAX | TAX1contactin 2 (axonal)-HPRD,BioGRID12139915 
MACF1ABP620 | ACF7 | FLJ45612 | FLJ46776 | KIAA0465 | KIAA1251 | MACF | OFC4microtubule-actin crosslinking factor 1-HPRD12421765 
MAGI3MAGI-3 | MGC163281 | RP4-730K3.1 | dJ730K3.2membrane associated guanylate kinase, WW and PDZ domain containing 3-HPRD12421765 
NFASCDKFZp686P2250 | FLJ46866 | KIAA0756 | NF | NRCAMLneurofascin homolog (chicken)-HPRD11724816 
PTPRBDKFZp686E2262 | DKFZp686H15164 | FLJ44133 | HPTP-BETA | HPTPB | MGC142023 | MGC59935 | PTPB | R-PTP-BETA | VEPTPprotein tyrosine phosphatase, receptor type, B-HPRD,BioGRID9049255 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_L1CAM_INTERACTIONS 8662All SZGR genes in this pathway
REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS 2319All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_DN 4629All SZGR genes in this pathway
DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP 5938All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP 255177All SZGR genes in this pathway
DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP 6437All SZGR genes in this pathway
JAEGER_METASTASIS_DN 258141All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP 185126All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP 157104All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP 4430All SZGR genes in this pathway
ODONNELL_TFRC_TARGETS_UP 456228All SZGR genes in this pathway
ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP 8350All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
CHEBOTAEV_GR_TARGETS_DN 12073All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_DN 4831All SZGR genes in this pathway
TERAMOTO_OPN_TARGETS_CLUSTER_8 87All SZGR genes in this pathway
WEINMANN_ADAPTATION_TO_HYPOXIA_DN 4133All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_DN 203134All SZGR genes in this pathway
LIAO_METASTASIS 539324All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_A 10063All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
KANG_IMMORTALIZED_BY_TERT_UP 8961All SZGR genes in this pathway
PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN 162102All SZGR genes in this pathway
PETROVA_PROX1_TARGETS_DN 6438All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_UP 9864All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_DN 14294All SZGR genes in this pathway
MAHAJAN_RESPONSE_TO_IL1A_UP 8152All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_DN 220147All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_UV 6243All SZGR genes in this pathway
KYNG_DNA_DAMAGE_UP 226164All SZGR genes in this pathway
COATES_MACROPHAGE_M1_VS_M2_UP 8152All SZGR genes in this pathway
LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP 7451All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN 258160All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_UP 170107All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_UP 430288All SZGR genes in this pathway
ZHENG_GLIOBLASTOMA_PLASTICITY_UP 250168All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_UP 13993All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
PEDRIOLI_MIR31_TARGETS_DN 418245All SZGR genes in this pathway
BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE 15186All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_UP 489314All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124/506833839m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-153125712631Ahsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-18214571463m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-191408414m8hsa-miR-191brainCAACGGAAUCCCAAAAGCAGCU
miR-218196319691Ahsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-30-3p17171723m8hsa-miR-30a-3pCUUUCAGUCGGAUGUUUGCAGC
hsa-miR-30e-3pCUUUCAGUCGGAUGUUUACAGC
miR-4318198261A,m8hsa-miR-431UGUCUUGCAGGCCGUCAUGCA
miR-448125712631Ahsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
miR-505153015361Ahsa-miR-505GUCAACACUUGCUGGUUUCCUC
miR-539147214781Ahsa-miR-539GGAGAAAUUAUCCUUGGUGUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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