Gene Page: REV3L

Summary
GeneID  5980
Symbol  REV3L
Synonyms  POLZ|REV3
Description  REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
See related  HGNC:9968|MIM:602776|Ensembl:ENSG00000009413|HPRD:04145|
Locus tag  -
Gene type  protein-coding
Map location  6q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003677DNA bindingIEA-
GO:0003887DNA-directed DNA polymerase activityTAS9618506 
GO:0016779nucleotidyltransferase activityIEA-
GO:0016740transferase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006281DNA repairIEA-
GO:0006261DNA-dependent DNA replicationTAS9618506 
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MAD2L1HSMAD2 | MAD2MAD2 mitotic arrest deficient-like 1 (yeast)-HPRD,BioGRID10660610 
hREV3 interacts with hMAD2.BIND10660610 
MAD2L2MAD2B | REV7MAD2 mitotic arrest deficient-like 2 (yeast)-HPRD,BioGRID10660610 |11485998 
hRev3 interacts with hRev7.BIND10660610 
REV1FLJ21523 | MGC163283 | MGC26225 | REV1LREV1 homolog (S. cerevisiae)-HPRD15189446 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_DNA_REPAIR 11259All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN 391222All SZGR genes in this pathway
AKL_HTLV1_INFECTION_DN 6841All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP 5844All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_UP 584356All SZGR genes in this pathway
WAKASUGI_HAVE_ZNF143_BINDING_SITES 5833All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN 483336All SZGR genes in this pathway
AMUNDSON_RESPONSE_TO_ARSENITE 217143All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
KAUFFMANN_DNA_REPAIR_GENES 230137All SZGR genes in this pathway
KAUFFMANN_DNA_REPLICATION_GENES 14787All SZGR genes in this pathway
WONG_IFNA2_RESISTANCE_UP 1610All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_UP 4936All SZGR genes in this pathway
NGUYEN_NOTCH1_TARGETS_DN 8667All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_DN 10170All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_DN 318220All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G6 153112All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D8 4029All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 473224All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_2D_UP 6946All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_POOR_SURVIVAL_UP 3122All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_DN 209137All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN 238145All SZGR genes in this pathway
GABRIELY_MIR21_TARGETS 289187All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
KUMAR_PATHOGEN_LOAD_BY_MACROPHAGES 275155All SZGR genes in this pathway
KUMAR_AUTOPHAGY_NETWORK 7146All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1017978041A,m8hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-142-5p4024091A,m8hsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-1447988041Ahsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-1459129191A,m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-17-5p/20/93.mr/106/519.d4014071Ahsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-1946776831Ahsa-miR-194UGUAACAGCAACUCCAUGUGGA
miR-203.1750756m8hsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-221/2225855911Ahsa-miR-221brainAGCUACAUUGUCUGCUGGGUUUC
hsa-miR-222brainAGCUACAUCUGGCUACUGGGUCUC
miR-25/32/92/363/367470476m8hsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
hsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-296571m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
miR-323466472m8hsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-3636626681Ahsa-miR-363AUUGCACGGUAUCCAUCUGUAA
hsa-miR-363AUUGCACGGUAUCCAUCUGUAA
miR-365645651m8hsa-miR-365UAAUGCCCCUAAAAAUCCUUAU
miR-3817427481Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-493-5p1881951A,m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-4956756811Ahsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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