Gene Page: RREB1

Summary
GeneID  6239
Symbol  RREB1
Synonyms  FINB|HNT|LZ321|RREB-1|Zep-1
Description  ras responsive element binding protein 1
See related  HGNC:10449|MIM:602209|Ensembl:ENSG00000124782|HPRD:03733|
Locus tag  RP11-69L16.1
Gene type  protein-coding
Map location  6p25
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0159 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RAPGEF50.930.86
LANCL10.900.89
PRUNE20.900.82
ENPP40.890.87
ENDOD10.890.82
FAM73A0.890.87
ARFGEF20.890.88
MFSD60.890.88
CLIP40.890.82
PCDH90.880.81
Top 10 negatively co-expressed genes
BCL7C-0.47-0.52
AC006276.2-0.47-0.48
RPL35-0.44-0.50
RPL36-0.43-0.48
TBC1D10A-0.43-0.35
ST20-0.42-0.49
RPL12-0.42-0.42
RPLP1-0.41-0.42
C9orf46-0.41-0.41
RPL31-0.40-0.46
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
GO:0008270zinc ion bindingIEA-
GO:0016563transcription activator activityTAS9305772 
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentTAS9305772 
GO:0006350transcriptionIEA-
GO:0006366transcription from RNA polymerase II promoterTAS8816445 
GO:0007265Ras protein signal transductionTAS8816445 
GO:0007275multicellular organismal developmentTAS8816445 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusTAS9305772 
GO:0005737cytoplasmTAS9305772 
GO:0016607nuclear speckIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
NEUROD1BETA2 | BHF-1 | NEUROD | bHLHa3neurogenic differentiation 1-HPRD12482979 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
HOOI_ST7_TARGETS_DN 12378All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_DN 244147All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP 170114All SZGR genes in this pathway
MIDORIKAWA_AMPLIFIED_IN_LIVER_CANCER 5538All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP 479299All SZGR genes in this pathway
THEODOROU_MAMMARY_TUMORIGENESIS 3124All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_UP 292168All SZGR genes in this pathway
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN 8567All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
BURTON_ADIPOGENESIS_5 12678All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_UP 210124All SZGR genes in this pathway
TAYLOR_METHYLATED_IN_ACUTE_LYMPHOBLASTIC_LEUKEMIA 7752All SZGR genes in this pathway
YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_DN 6531All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7 7646All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_DN 3720All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
DELACROIX_RAR_BOUND_ES 462273All SZGR genes in this pathway
RATTENBACHER_BOUND_BY_CELF1 467251All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_DN 428246All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-10199510011Ahsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-124.12182251A,m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/5062172241A,m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-14499510011Ahsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-1454574641A,m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-155335341m8hsa-miR-155UUAAUGCUAAUCGUGAUAGGGG
miR-234724781Ahsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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