Gene Page: SLC16A1

Summary
GeneID  6566
Symbol  SLC16A1
Synonyms  FLJ36745|HHF7|MCT|MCT1|MGC44475
Description  solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
See related  HGNC:10922|MIM:600682|Ensembl:ENSG00000155380|HPRD:02816|
Locus tag  -
Gene type  protein-coding
Map location  1p12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SCFD10.720.69
SSB0.700.66
ORC3L0.680.67
NAP1L10.670.60
PPIL40.660.57
PPP2R2A0.660.60
ZW100.660.60
OLA10.660.60
PRPF180.650.60
ECHDC10.650.63
Top 10 negatively co-expressed genes
MT-CO2-0.50-0.48
AF347015.2-0.48-0.49
AF347015.33-0.48-0.46
AF347015.31-0.47-0.46
AF347015.21-0.47-0.43
MT-CYB-0.47-0.45
IFI27-0.46-0.47
AF347015.8-0.46-0.44
AF347015.26-0.46-0.43
AF347015.9-0.45-0.45
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI17353931 
GO:0005215transporter activityIEA-
GO:0015355secondary active monocarboxylate transmembrane transporter activityIEA-
GO:0015293symporter activityIEA-
GO:0015130mevalonate transmembrane transporter activityTAS1429658 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0015728mevalonate transportTAS1429658 
GO:0015711organic anion transportIEA-
GO:0006810transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionTAS8124722 
GO:0016021integral to membraneIEA-
GO:0016021integral to membraneTAS1429658 
GO:0005886plasma membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AP1S1AP19 | CLAPS1 | FLJ92436 | SIGMA1A | WUGSC:H_DJ0747G18.2adaptor-related protein complex 1, sigma 1 subunitAffinity Capture-MSBioGRID17353931 
BSG5F7 | CD147 | EMMPRIN | M6 | OK | TCSFbasigin (Ok blood group)-HPRD,BioGRID10921872 
DEGS1DEGS | DES1 | Des-1 | FADS7 | MGC5079 | MIG15 | MLDdegenerative spermatocyte homolog 1, lipid desaturase (Drosophila)Affinity Capture-MSBioGRID17353931 
SERINC3AIGP1 | DIFF33 | SBBI99 | TDE | TDE1 | TMS-1serine incorporator 3Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 4832All SZGR genes in this pathway
REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 14185All SZGR genes in this pathway
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 9165All SZGR genes in this pathway
REACTOME_BASIGIN_INTERACTIONS 3023All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 241157All SZGR genes in this pathway
REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS 8954All SZGR genes in this pathway
REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS 116All SZGR genes in this pathway
REACTOME_PYRUVATE_METABOLISM 1914All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
WINTER_HYPOXIA_UP 9257All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP 14686All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
DOANE_BREAST_CANCER_CLASSES_DN 3426All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP 204140All SZGR genes in this pathway
UDAYAKUMAR_MED1_TARGETS_UP 13582All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_UP 457269All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_UP 238144All SZGR genes in this pathway
SENESE_HDAC2_TARGETS_UP 11466All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP 293179All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP 12073All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_BASAL 330217All SZGR genes in this pathway
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL 330215All SZGR genes in this pathway
SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM 15993All SZGR genes in this pathway
HEIDENBLAD_AMPLICON_8Q24_UP 4023All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_UP 201127All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
BENPORATH_ES_1 379235All SZGR genes in this pathway
SUNG_METASTASIS_STROMA_UP 11070All SZGR genes in this pathway
MORI_IMMATURE_B_LYMPHOCYTE_DN 9055All SZGR genes in this pathway
MORI_MATURE_B_LYMPHOCYTE_DN 7543All SZGR genes in this pathway
ONDER_CDH1_TARGETS_1_DN 169102All SZGR genes in this pathway
LEE_LIVER_CANCER_ACOX1_UP 6440All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_DN 309206All SZGR genes in this pathway
SCHUHMACHER_MYC_TARGETS_UP 8057All SZGR genes in this pathway
LEE_LIVER_CANCER_CIPROFIBRATE_UP 6042All SZGR genes in this pathway
COLLER_MYC_TARGETS_UP 2519All SZGR genes in this pathway
BHATTACHARYA_EMBRYONIC_STEM_CELL 8960All SZGR genes in this pathway
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN 7345All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_DN 12986All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN 163115All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN 172107All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_16HR_UP 225139All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_MATURE_CELL 293160All SZGR genes in this pathway
YAMAZAKI_TCEB3_TARGETS_UP 175116All SZGR genes in this pathway
RHODES_UNDIFFERENTIATED_CANCER 6944All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
BURTON_ADIPOGENESIS_PEAK_AT_8HR 3931All SZGR genes in this pathway
MAHAJAN_RESPONSE_TO_IL1A_UP 8152All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_UP 3120All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_UP 388234All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN 409268All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_UP 170107All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN 315197All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_UP 294199All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE 242168All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_UP 13995All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP 5838All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_UP 212128All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_DN 5033All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 456285All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
IRITANI_MAD1_TARGETS_DN 4730All SZGR genes in this pathway
VALK_AML_CLUSTER_15 3119All SZGR genes in this pathway
VALK_AML_WITH_CEBPA 3727All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN 4026All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP 176110All SZGR genes in this pathway
STEIN_ESR1_TARGETS 8555All SZGR genes in this pathway
STEIN_ESRRA_TARGETS 535325All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_UP 7253All SZGR genes in this pathway
WONG_EMBRYONIC_STEM_CELL_CORE 335193All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP 221135All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN 207139All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN 374217All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP 229149All SZGR genes in this pathway
PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN 157106All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_UP 163111All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_UP 279155All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.12792861A,m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/5062782851A,m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-298187m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
miR-3742682741Ahsa-miR-374UUAUAAUACAACCUGAUAAGUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.