Gene Page: TCN2

Summary
GeneID  6948
Symbol  TCN2
Synonyms  D22S676|D22S750|TC2
Description  transcobalamin II; macrocytic anemia
See related  HGNC:11653|MIM:275350|Ensembl:ENSG00000185339|HPRD:02037|
Locus tag  -
Gene type  protein-coding
Map location  22q12.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TPD520.910.91
ENPP50.880.89
REEP50.880.89
SNX100.870.90
ATP1B10.870.91
EPDR10.870.90
KRT222P0.860.83
CCNDBP10.860.86
NSF0.860.89
RCAN20.860.90
Top 10 negatively co-expressed genes
BCL7C-0.45-0.53
NME4-0.45-0.55
SH3BP2-0.45-0.45
RBMX2-0.43-0.43
PDE9A-0.43-0.39
SH2D2A-0.42-0.45
RPL28-0.42-0.51
RPL18-0.41-0.48
RPS19P3-0.41-0.49
SH2B2-0.41-0.42
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0015087cobalt ion transmembrane transporter activityIEA-
GO:0031419cobalamin bindingIEA-
GO:0050897cobalt ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006824cobalt ion transportIEA-
GO:0006811ion transportIEA-
GO:0015889cobalamin transportIEA-
GO:0015889cobalamin transportTAS3782074 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005615extracellular spaceTAS1708393 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
HORIUCHI_WTAP_TARGETS_UP 306188All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP 2616All SZGR genes in this pathway
WANG_BARRETTS_ESOPHAGUS_UP 5127All SZGR genes in this pathway
CEBALLOS_TARGETS_OF_TP53_AND_MYC_DN 3831All SZGR genes in this pathway
SHEPARD_BMYB_MORPHOLINO_DN 200112All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN 162102All SZGR genes in this pathway
PETROVA_PROX1_TARGETS_DN 6438All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR 14984All SZGR genes in this pathway
LEIN_CHOROID_PLEXUS_MARKERS 10361All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_DN 240153All SZGR genes in this pathway
HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN 7561All SZGR genes in this pathway
ZHANG_TLX_TARGETS_36HR_UP 221150All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
ZHANG_TLX_TARGETS_UP 10878All SZGR genes in this pathway
ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP 3225All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_UP 181106All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_DN 253192All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3 718401All SZGR genes in this pathway
MIKKELSEN_NPC_ICP_WITH_H3K4ME3 445257All SZGR genes in this pathway
WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 5531All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_UP 169105All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-2149096m8hsa-miR-214brainACAGCAGGCACAGACAGGCAG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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