Gene Page: TRIP6

Summary
GeneID  7205
Symbol  TRIP6
Synonyms  MGC10556|MGC10558|MGC29959|MGC3837|MGC4423|OIP1|ZRP-1
Description  thyroid hormone receptor interactor 6
See related  HGNC:12311|MIM:602933|Ensembl:ENSG00000087077|HPRD:04242|
Locus tag  tcag7.1300
Gene type  protein-coding
Map location  7q22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0561 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
C22orf300.940.96
KIAA14090.940.96
KDM2A0.940.96
ZNF3180.930.95
MBD50.930.95
NCOR10.930.94
LYST0.920.94
UBN10.920.94
ATXN70.920.94
ZSCAN290.920.94
Top 10 negatively co-expressed genes
AF347015.31-0.73-0.78
MT-CO2-0.71-0.76
HIGD1B-0.71-0.79
AF347015.21-0.70-0.81
FXYD1-0.70-0.74
IFI27-0.69-0.74
CST3-0.69-0.76
HSD17B14-0.68-0.72
S100A16-0.68-0.73
AF347015.27-0.68-0.72
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005149interleukin-1 receptor bindingIDA15657077 
GO:0008270zinc ion bindingIEA-
GO:0019900kinase bindingIPI15657077 
GO:0042802identical protein bindingIPI17353931 
GO:0046872metal ion bindingIEA-
GO:0046966thyroid hormone receptor bindingNAS9598321 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008588release of cytoplasmic sequestered NF-kappaBIDA15657077 
GO:0048041focal adhesion formationNAS14688263 
GO:0030335positive regulation of cell migrationIMP14688263 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005925focal adhesionIDA14688263 
GO:0045323interleukin-1 receptor complexIDA15657077 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTA1ACTA | ASMA | CFTD | CFTD1 | CFTDM | MPFD | NEM1 | NEM2 | NEM3actin, alpha 1, skeletal muscleCo-localizationBioGRID14688263 
AFAP1L1FLJ36748 | MGC149773actin filament associated protein 1-like 1Affinity Capture-MSBioGRID17353931 
AQP1AQP-CHIP | CHIP28 | CO | MGC26324aquaporin 1 (Colton blood group)Two-hybridBioGRID16189514 
BCAR1CAS | CAS1 | CASS1 | CRKAS | P130Casbreast cancer anti-estrogen resistance 1-HPRD,BioGRID11782456 |14688263 
CATSPER1CATSPER | MGC33335 | MGC33368cation channel, sperm associated 1Two-hybridBioGRID16189514 
FAM124BFLJ22746family with sequence similarity 124BTwo-hybridBioGRID16189514 
FAM46CFLJ20202family with sequence similarity 46, member CTwo-hybridBioGRID16189514 
FHL3MGC19547 | MGC23614 | MGC8696 | SLIM2four and a half LIM domains 3Two-hybridBioGRID16189514 
HOXA1BSAS | HOX1 | HOX1F | MGC45232homeobox A1Two-hybridBioGRID16189514 
HOXA9ABD-B | HOX1 | HOX1.7 | HOX1G | MGC1934homeobox A9Affinity Capture-Western
Two-hybrid		BioGRID16189514 
ILF3CBTF | DRBF | DRBP76 | MMP4 | MPHOSPH4 | MPP4 | NF-AT-90 | NF110 | NF90 | NFAR | NFAR-1 | NFAR2 | TCP110 | TCP80interleukin enhancer binding factor 3, 90kDaTwo-hybridBioGRID16189514 
KCTD5FLJ20040potassium channel tetramerisation domain containing 5Affinity Capture-MSBioGRID17353931 
KIAA1683MGC131731KIAA1683Two-hybridBioGRID16189514 
LOC116349-hypothetical protein BC014011Two-hybridBioGRID16189514 
LPAR2EDG-4 | EDG4 | FLJ93869 | LPA2lysophosphatidic acid receptor 2Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID14688263 
MOBKL1BC2orf6 | FLJ10788 | FLJ11595 | MATS1 | MOB1 | MOBK1B | Mob4BMOB1, Mps One Binder kinase activator-like 1B (yeast)Affinity Capture-MSBioGRID17353931 
NCK2GRB4 | NCKbetaNCK adaptor protein 2Two-hybridBioGRID16189514 
NEDD9CAS-L | CAS2 | CASL | CASS2 | HEF1 | dJ49G10.2 | dJ761I2.1neural precursor cell expressed, developmentally down-regulated 9-HPRD,BioGRID11782456 
NUP210FLJ22389 | GP210 | KIAA0906 | POM210nucleoporin 210kDa-HPRD,BioGRID11782456 
ODF1HSPB10 | MGC129928 | MGC129929 | ODF | ODF2 | ODF27 | ODFP | ODFPG | ODFPGA | ODFPGB | RT7 | SODFouter dense fiber of sperm tails 1-HPRD,BioGRID12533418 
P4HBDSI | ERBA2L | GIT | PDI | PDIA1 | PHDB | PO4DB | PO4HB | PROHBprocollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptideAffinity Capture-MSBioGRID17353931 
PDLIM4RILPDZ and LIM domain 4-HPRD,BioGRID10826496 
POM121DKFZp586G1822 | DKFZp586P2220 | FLJ41820 | KIAA0618 | MGC3792 | POM121APOM121 membrane glycoprotein (rat)Two-hybridBioGRID16189514 
PPP1R16AMGC14333 | MYPT3protein phosphatase 1, regulatory (inhibitor) subunit 16ATwo-hybridBioGRID16189514 
PTK2FADK | FAK | FAK1 | pp125FAKPTK2 protein tyrosine kinase 2-HPRD,BioGRID14688263 
PTPN13DKFZp686J1497 | FAP-1 | PNP1 | PTP-BAS | PTP-BL | PTP1E | PTPL1 | PTPLEprotein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)-HPRD,BioGRID10826496 
PXNFLJ16691paxillin-HPRD,BioGRID14688263 
RNMTL1FLJ10581 | HC90RNA methyltransferase like 1Affinity Capture-MSBioGRID17353931 
RPS14EMTBribosomal protein S14Affinity Capture-MSBioGRID17353931 
SONBASS1 | C21orf50 | DBP-5 | FLJ21099 | FLJ33914 | KIAA1019 | NREBP | SON3SON DNA binding protein-HPRD11782456 
SRCASV | SRC1 | c-SRC | p60-Srcv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)-HPRD,BioGRID14688263 
STOMBND7 | EPB7 | EPB72stomatinAffinity Capture-MSBioGRID17353931 
THRAP3FLJ22082 | MGC133082 | MGC133083 | TRAP150thyroid hormone receptor associated protein 3Affinity Capture-MSBioGRID17353931 
TPM4-tropomyosin 4-HPRD,BioGRID11782456 
VCLCMD1W | MVCLvinculinTwo-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY 6247All SZGR genes in this pathway
PID_LYSOPHOSPHOLIPID_PATHWAY 6653All SZGR genes in this pathway
PID_AP1_PATHWAY 7060All SZGR genes in this pathway
HOLLMANN_APOPTOSIS_VIA_CD40_DN 267178All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP 12973All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN 182111All SZGR genes in this pathway
TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN 198110All SZGR genes in this pathway
HOOI_ST7_TARGETS_UP 9457All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP 204140All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_UP 316190All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
PROVENZANI_METASTASIS_DN 13694All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_3_DN 229142All SZGR genes in this pathway
TOMIDA_METASTASIS_DN 1811All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
UEDA_PERIFERAL_CLOCK 169111All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 6733All SZGR genes in this pathway
RAMALHO_STEMNESS_UP 206118All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
CHIBA_RESPONSE_TO_TSA_UP 5233All SZGR genes in this pathway
MURAKAMI_UV_RESPONSE_6HR_UP 3731All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
HELLER_HDAC_TARGETS_UP 317208All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN 274165All SZGR genes in this pathway
QI_PLASMACYTOMA_DN 10063All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_BRCA1_UP 3618All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_UP 181106All SZGR genes in this pathway
WONG_EMBRYONIC_STEM_CELL_CORE 335193All SZGR genes in this pathway
KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_UP 4030All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_CLASSICAL 162122All SZGR genes in this pathway
LU_EZH2_TARGETS_UP 295155All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway
BOUDOUKHA_BOUND_BY_IGF2BP2 11159All SZGR genes in this pathway


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