Gene Page: SEMA3B

Summary
GeneID  7869
Symbol  SEMA3B
Synonyms  FLJ34863|LUCA-1|SEMA5|SEMAA|SemA|semaV
Description  sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
See related  HGNC:10724|MIM:601281|Ensembl:ENSG00000012171|HPRD:03179|
Locus tag  -
Gene type  protein-coding
Map location  3p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenia, schizophrenias]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ABAT0.840.86
SLC30A10.830.81
FAM120A0.820.83
SPRED10.820.81
ACADSB0.810.80
PTPN110.800.76
PURA0.800.79
PTPRE0.790.78
APLP20.790.80
ADAM90.790.79
Top 10 negatively co-expressed genes
RP9P-0.45-0.49
SNHG12-0.44-0.51
AL022328.1-0.44-0.41
ACSM3-0.44-0.42
FAM159B-0.43-0.54
AC120053.1-0.43-0.45
AC135724.1-0.41-0.38
RPS21-0.40-0.48
IL32-0.40-0.32
RPL31-0.39-0.47
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007411axon guidanceTASaxon (GO term level: 13)8633026 
GO:0007267cell-cell signalingTAS8633026 
GO:0007275multicellular organismal developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005783endoplasmic reticulumTAS8633026 
GO:0016020membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
NRP1BDCA4 | CD304 | DKFZp686A03134 | DKFZp781F1414 | NP1 | NRP | VEGF165Rneuropilin 1-HPRD10196546 
NRP2MGC126574 | NP2 | NPN2 | PRO2714 | VEGF165R2neuropilin 2-HPRD10196546 
SEMA3AHsema-I | Hsema-III | MGC133243 | SEMA1 | SEMAD | SEMAIII | SEMAL | SemD | coll-1sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A-HPRD10196546 
SEMA3BFLJ34863 | LUCA-1 | SEMA5 | SEMAA | SemA | semaVsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B-HPRD10196546 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_AXON_GUIDANCE 129103All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN 182111All SZGR genes in this pathway
DOANE_BREAST_CANCER_ESR1_UP 11272All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_DN 10459All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_DN 232139All SZGR genes in this pathway
SENESE_HDAC2_TARGETS_DN 13377All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_DN 536332All SZGR genes in this pathway
NAGASHIMA_NRG1_SIGNALING_UP 176123All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP 9760All SZGR genes in this pathway
BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN 4534All SZGR genes in this pathway
SHI_SPARC_TARGETS_DN 138All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_UP 292168All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
LE_EGR2_TARGETS_DN 10884All SZGR genes in this pathway
ZUCCHI_METASTASIS_DN 4429All SZGR genes in this pathway
STOSSI_RESPONSE_TO_ESTRADIOL 5035All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
MACLACHLAN_BRCA1_TARGETS_DN 1612All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
NIELSEN_SCHWANNOMA_UP 1816All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_UP 202115All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_UP 8847All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
SANSOM_APC_MYC_TARGETS 217138All SZGR genes in this pathway
SANSOM_APC_TARGETS_REQUIRE_MYC 210123All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION 8159All SZGR genes in this pathway
KYNG_DNA_DAMAGE_DN 195135All SZGR genes in this pathway
LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_DN 4531All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN 154101All SZGR genes in this pathway
AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 10963All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP 9761All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_UP 172109All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
LABBE_WNT3A_TARGETS_DN 9753All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_DN 546362All SZGR genes in this pathway
HUPER_BREAST_BASAL_VS_LUMINAL_DN 5944All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN 264159All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_15 3523All SZGR genes in this pathway
BAE_BRCA1_TARGETS_DN 3227All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP 229149All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP 324193All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP 211131All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway
ISSAEVA_MLL2_TARGETS 6235All SZGR genes in this pathway
PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN 10677All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_2HR 85All SZGR genes in this pathway
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR 8549All SZGR genes in this pathway
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR 12873All SZGR genes in this pathway
NABA_ECM_AFFILIATED 17189All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-273543601Ahsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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