Gene Page: HIST2H2BE

Summary
GeneID  8349
Symbol  HIST2H2BE
Synonyms  GL105|H2B|H2B.1|H2B/q|H2BFQ|MGC119802|MGC119804|MGC129733|MGC129734
Description  histone cluster 2, H2be
See related  HGNC:4760|MIM:601831|Ensembl:ENSG00000184678|HPRD:03494|
Locus tag  -
Gene type  protein-coding
Map location  1q21-q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CLIC10.740.65
EFNA40.710.45
CNN30.710.46
VIM0.700.45
TGIF10.690.42
RFXANK0.680.60
IQGAP20.680.22
LRRC3B0.670.47
FKBP100.670.48
PDLIM30.670.50
Top 10 negatively co-expressed genes
SYNJ2-0.32-0.35
ITPR1-0.31-0.35
TDRD6-0.31-0.40
JAKMIP3-0.31-0.35
ITSN2-0.31-0.39
KIF16B-0.31-0.34
PIP5K2A-0.30-0.34
GPATCH4-0.30-0.40
GREM1-0.29-0.33
MYH7B-0.29-0.26
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingNAS1469070 
GO:0005515protein bindingIPI17353931 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006334nucleosome assemblyNAS1469070 
GO:0042742defense response to bacteriumIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000786nucleosomeNAS1469070 
GO:0005634nucleusIEA-
GO:0005694chromosomeIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BRD7BP75 | CELTIX1 | NAG4bromodomain containing 7-HPRD12489984 
DNTTIP2ERBP | FCF2 | HSU15552 | LPTS-RP2 | MGC163494 | RP4-561L24.1 | TdIF2deoxynucleotidyltransferase, terminal, interacting protein 2-HPRD12786946 
DYRK2FLJ21217 | FLJ21365dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2-HPRD9748265 
HIRADGCR1 | TUP1 | TUPLE1HIR histone cell cycle regulation defective homolog A (S. cerevisiae)-HPRD9710638 
HIRIP3-HIRA interacting protein 3-HPRD9710638 
HSPD1CPN60 | GROEL | HSP60 | HSP65 | HuCHA60 | SPG13heat shock 60kDa protein 1 (chaperonin)-HPRD,BioGRID9724719 
KPNA1IPOA5 | NPI-1 | RCH2 | SRP1karyopherin alpha 1 (importin alpha 5)-HPRD11824786 
LALBAMGC138521 | MGC138523lactalbumin, alpha--HPRD12888554 
NAP1L4MGC4565 | NAP2 | NAP2L | hNAP2nucleosome assembly protein 1-like 4-HPRD9325046 
PARP3ADPRT3 | ADPRTL2 | ADPRTL3 | IRT1 | hPARP-3 | pADPRT-3poly (ADP-ribose) polymerase family, member 3Affinity Capture-MSBioGRID17353931 
PTMAMGC104802 | TMSAprothymosin, alpha-HPRD11310559 
RCC1CHC1 | RCC1-Iregulator of chromosome condensation 1-HPRD11375490 
TBL1XEBI | SMAP55 | TBL1transducin (beta)-like 1X-linkedH2B interacts with TBL1.BIND12628926 
-HPRD,BioGRID12628926 
TBL1XR1C21 | DC42 | FLJ12894 | IRA1 | TBLR1transducin (beta)-like 1 X-linked receptor 1H2B interacts with TBLR1.BIND12628926 
Reconstituted ComplexBioGRID12628926 
TGM2G-ALPHA-h | GNAH | TG2 | TGCtransglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)-HPRD9973324 
TNPO1IPO2 | KPNB2 | MIP | MIP1 | TRNtransportin 1-HPRD11824786 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 140100All SZGR genes in this pathway
REACTOME_MEIOSIS 11681All SZGR genes in this pathway
REACTOME_CELL_CYCLE 421253All SZGR genes in this pathway
REACTOME_RNA_POL_I_TRANSCRIPTION 8964All SZGR genes in this pathway
REACTOME_TRANSCRIPTION 210127All SZGR genes in this pathway
REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 12280All SZGR genes in this pathway
REACTOME_CHROMOSOME_MAINTENANCE 12280All SZGR genes in this pathway
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 6443All SZGR genes in this pathway
REACTOME_RNA_POL_I_PROMOTER_OPENING 6249All SZGR genes in this pathway
REACTOME_MEIOTIC_RECOMBINATION 8662All SZGR genes in this pathway
REACTOME_MEIOTIC_SYNAPSIS 7357All SZGR genes in this pathway
REACTOME_AMYLOIDS 8363All SZGR genes in this pathway
REACTOME_PACKAGING_OF_TELOMERE_ENDS 4840All SZGR genes in this pathway
REACTOME_TELOMERE_MAINTENANCE 7557All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN 349157All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP 177110All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN 406230All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN 329219All SZGR genes in this pathway
GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN 4732All SZGR genes in this pathway
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN 9557All SZGR genes in this pathway
GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP 6647All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP 6446All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_UP 1915All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
SANCHEZ_MDM2_TARGETS 1510All SZGR genes in this pathway
HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP 2315All SZGR genes in this pathway
HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP 3618All SZGR genes in this pathway
HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP 8157All SZGR genes in this pathway
XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_DN 2012All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
WANG_RESPONSE_TO_PACLITAXEL_VIA_MAPK8_UP 149All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP 769437All SZGR genes in this pathway
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN 165104All SZGR genes in this pathway
BENPORATH_OCT4_TARGETS 290172All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
GNATENKO_PLATELET_SIGNATURE 4828All SZGR genes in this pathway
FRASOR_RESPONSE_TO_ESTRADIOL_DN 8252All SZGR genes in this pathway
REN_BOUND_BY_E2F 6140All SZGR genes in this pathway
VERNELL_RETINOBLASTOMA_PATHWAY_DN 2213All SZGR genes in this pathway
ALCALAY_AML_BY_NPM1_LOCALIZATION_UP 14083All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_UP 6446All SZGR genes in this pathway
VERHAAK_AML_WITH_NPM1_MUTATED_UP 183111All SZGR genes in this pathway
NOUZOVA_TRETINOIN_AND_H4_ACETYLATION 14385All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP 314201All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
KAYO_AGING_MUSCLE_DN 12376All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
ZHENG_RESPONSE_TO_ARSENITE_UP 1814All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
GEORGANTAS_HSC_MARKERS 7147All SZGR genes in this pathway
LIANG_SILENCED_BY_METHYLATION_UP 3218All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C3 2015All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G2 3018All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
HELLER_HDAC_TARGETS_UP 317208All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN 154101All SZGR genes in this pathway
CAMPS_COLON_CANCER_COPY_NUMBER_DN 7434All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_UP 6748All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
RAY_TARGETS_OF_P210_BCR_ABL_FUSION_UP 1813All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP 188121All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
KOBAYASHI_EGFR_SIGNALING_24HR_UP 10165All SZGR genes in this pathway
HAHTOLA_CTCL_CUTANEOUS 2619All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G24 2819All SZGR genes in this pathway
DASU_IL6_SIGNALING_UP 5944All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_M_G1 14895All SZGR genes in this pathway
RAGHAVACHARI_PLATELET_SPECIFIC_GENES 7046All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_DN 428246All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-23109511011Ahsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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