Gene Page: SLC25A12

Summary
GeneID  8604
Symbol  SLC25A12
Synonyms  ARALAR|ARALAR1
Description  solute carrier family 25 (mitochondrial carrier, Aralar), member 12
See related  HGNC:10982|MIM:603667|Ensembl:ENSG00000115840|HPRD:04719|
Locus tag  -
Gene type  protein-coding
Map location  2q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenic]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 4 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
LST10.790.79
GMFG0.780.78
PYCARD0.730.68
IFI27L20.720.63
TREM20.720.65
VAMP50.710.72
CD630.710.69
TYROBP0.690.69
MGST20.690.71
LY960.690.73
Top 10 negatively co-expressed genes
SPTAN1-0.51-0.62
MYO18A-0.51-0.56
SUPT6H-0.51-0.56
PTPN23-0.51-0.60
HNRNPUL2-0.50-0.51
TCOF1-0.50-0.60
TNKS1BP1-0.50-0.57
SMG6-0.50-0.57
USP20-0.50-0.57
KDM5C-0.50-0.61
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0015183L-aspartate transmembrane transporter activityIDAglutamate (GO term level: 9)11566871 
GO:0005313L-glutamate transmembrane transporter activityIDAglutamate (GO term level: 9)11566871 
GO:0005488bindingIEA-
GO:0005509calcium ion bindingIDA9722566 
GO:0005215transporter activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0015813L-glutamate transportIDAglutamate (GO term level: 9)11566871 
GO:0015810aspartate transportIDAglutamate (GO term level: 9)11566871 
GO:0006810transportIEA-
GO:0043490malate-aspartate shuttleIDA11566871 
GO:0051592response to calcium ionIDA11566871 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005739mitochondrionIDA9722566 |11566871 
GO:0005743mitochondrial inner membraneIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneNAS9722566 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
C20orf24PNAS-11 | RIP5chromosome 20 open reading frame 24Affinity Capture-MSBioGRID17353931 
PELOCGI-17 | PRO1770pelota homolog (Drosophila)Affinity Capture-MSBioGRID17353931 
PHLDA3TIH1pleckstrin homology-like domain, family A, member 3Affinity Capture-MSBioGRID17353931 
PNKPPNKpolynucleotide kinase 3'-phosphataseAffinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 5824All SZGR genes in this pathway
REACTOME_GLUCONEOGENESIS 3421All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
REACTOME_GLUCOSE_METABOLISM 6942All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN 8871All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP 769437All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP 176115All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
MAHAJAN_RESPONSE_TO_IL1A_DN 7657All SZGR genes in this pathway
BILD_E2F3_ONCOGENIC_SIGNATURE 246153All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_UP 388234All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G 17196All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_DN 12071All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_UP 442263All SZGR genes in this pathway
STEIN_ESRRA_TARGETS 535325All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_30MIN_DN 15099All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_MIDDLE 9856All SZGR genes in this pathway
KRIEG_KDM3A_TARGETS_NOT_HYPOXIA 208107All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-3201942001Ahsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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