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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: UNC119

Summary

GeneID

9094

Symbol

UNC119

Synonyms

HRG4

Description

unc-119 homolog (C. elegans)

Locus tag

Gene type

protein-coding

Map location

17q11.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

MORF4L2

0.92

0.90

RAB18

0.91

RAB2A

0.90

0.88

PPP2CA

0.90

0.87

CMPK1

0.89

0.88

MRPS10

0.89

0.87

ATG5

0.89

SLC30A9

0.88

0.86

STRAP

0.88

0.85

PPP1CB

0.88

Top 10 negatively co-expressed genes

MT-CO2

-0.67

-0.55

AF347015.8

-0.67

-0.55

AF347015.21

-0.66

-0.48

AF347015.18

-0.66

-0.58

AF347015.2

-0.65

-0.54

AF347015.26

-0.65

-0.55

AF347015.33

-0.64

-0.53

MT-CYB

-0.63

-0.52

AF347015.15

-0.63

-0.53

FXYD1

-0.61

-0.55

Gene Ontology

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007268

synaptic transmission

TAS

neuron, Synap, Neurotransmitter (GO term level: 6)

9538874

GO:0007602

phototransduction

TAS

9538874

GO:0007601

visual perception

TAS

10329014

GO:0050896

response to stimulus

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005829

cytosol

TAS

9538874

GO:0005625

soluble fraction

TAS

9538874

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ALDH2	ALDH-E2 \| ALDHI \| ALDM \| MGC1806	aldehyde dehydrogenase 2 family (mitochondrial)	Two-hybrid	BioGRID	16169070
ANKRD24	KIAA1981	ankyrin repeat domain 24	Two-hybrid	BioGRID	16169070
ANXA3	ANX3	annexin A3	Two-hybrid	BioGRID	16169070
AOF2	BHC110 \| KDM1 \| KIAA0601 \| LSD1	amine oxidase (flavin containing) domain 2	Two-hybrid	BioGRID	16169070
ARL15	ARFRP2 \| FLJ20051	ADP-ribosylation factor-like 15	Two-hybrid	BioGRID	16169070
ARL2	ARFL2	ADP-ribosylation factor-like 2	HRG4 interacts with ARL2.	BIND	12527357
ARL2	ARFL2	ADP-ribosylation factor-like 2	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	12527357
ARL3	ARFL3	ADP-ribosylation factor-like 3	-	HPRD,BioGRID	11303027
ARL4D	ARF4L \| ARL6	ADP-ribosylation factor-like 4D	Two-hybrid	BioGRID	16169070
ASH2L	ASH2 \| ASH2L1 \| ASH2L2 \| Bre2	ash2 (absent, small, or homeotic)-like (Drosophila)	Two-hybrid	BioGRID	16169070
BCR	ALL \| BCR-ABL1 \| BCR1 \| CML \| D22S11 \| D22S662 \| FLJ16453 \| PHL	breakpoint cluster region	Two-hybrid	BioGRID	16169070
BTBD2	-	BTB (POZ) domain containing 2	Two-hybrid	BioGRID	16169070
BXDC2	BRIX \| FLJ11100	brix domain containing 2	Two-hybrid	BioGRID	16169070
C16orf74	MGC17624	chromosome 16 open reading frame 74	Two-hybrid	BioGRID	16189514
CBX8	HPC3 \| PC3 \| RC1	chromobox homolog 8 (Pc class homolog, Drosophila)	Two-hybrid	BioGRID	16169070
CCL18	AMAC-1 \| AMAC1 \| CKb7 \| DC-CK1 \| DCCK1 \| MIP-4 \| PARC \| SCYA18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	Two-hybrid	BioGRID	16169070
CD247	CD3-ZETA \| CD3H \| CD3Q \| CD3Z \| T3Z \| TCRZ	CD247 molecule	-	HPRD,BioGRID	14757743
CD4	CD4mut	CD4 molecule	-	HPRD,BioGRID	14757743
CDC42	CDC42Hs \| G25K	cell division cycle 42 (GTP binding protein, 25kDa)	Two-hybrid	BioGRID	16169070
CDKN2C	INK4C \| p18 \| p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	Two-hybrid	BioGRID	16169070
CETN3	CEN3 \| MGC12502 \| MGC138245	centrin, EF-hand protein, 3 (CDC31 homolog, yeast)	Two-hybrid	BioGRID	16169070
CKMT2	SMTCK	creatine kinase, mitochondrial 2 (sarcomeric)	Two-hybrid	BioGRID	16169070
CKS2	CKSHS2	CDC28 protein kinase regulatory subunit 2	Two-hybrid	BioGRID	16169070
COX17	MGC104397 \| MGC117386	COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)	Two-hybrid	BioGRID	16169070
CYB561D2	101F6 \| TSP10	cytochrome b-561 domain containing 2	Two-hybrid	BioGRID	16169070
EIF2S2	DKFZp686L18198 \| EIF2 \| EIF2B \| EIF2beta \| MGC8508	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	Two-hybrid	BioGRID	16169070
ERH	DROER \| FLJ27340	enhancer of rudimentary homolog (Drosophila)	Two-hybrid	BioGRID	16169070
FKBPL	DIR1 \| NG7 \| WISP39	FK506 binding protein like	Two-hybrid	BioGRID	16169070
FXYD6	-	FXYD domain containing ion transport regulator 6	Two-hybrid	BioGRID	16169070
FYN	MGC45350 \| SLK \| SYN	FYN oncogene related to SRC, FGR, YES	-	HPRD,BioGRID	14757743
GIPC2	FLJ20075 \| SEMCAP-2 \| SEMCAP2	GIPC PDZ domain containing family, member 2	Two-hybrid	BioGRID	16169070
GSTM4	GSTM4-4 \| GTM4 \| MGC131945 \| MGC9247	glutathione S-transferase mu 4	Two-hybrid	BioGRID	16169070
HCK	JTK9	hemopoietic cell kinase	-	HPRD,BioGRID	12496276
HLA-DQA1	CD \| CELIAC1 \| DQ-A1 \| FLJ27088 \| FLJ27328 \| GSE \| HLA-DQA \| MGC149527	major histocompatibility complex, class II, DQ alpha 1	Two-hybrid	BioGRID	16169070
HMGB1	DKFZp686A04236 \| HMG1 \| HMG3 \| SBP-1	high-mobility group box 1	Two-hybrid	BioGRID	16169070
HSPB3	HSPL27	heat shock 27kDa protein 3	Two-hybrid	BioGRID	16169070
HSPE1	CPN10 \| GROES \| HSP10	heat shock 10kDa protein 1 (chaperonin 10)	Two-hybrid	BioGRID	16169070
ID2	GIG8 \| ID2A \| ID2H \| MGC26389 \| bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	Two-hybrid	BioGRID	16169070
IL5RA	CD125 \| CDw125 \| HSIL5R3 \| IL5R \| MGC26560	interleukin 5 receptor, alpha	-	HPRD,BioGRID	12496276
ITSN1	ITSN \| MGC134948 \| MGC134949 \| SH3D1A \| SH3P17	intersectin 1 (SH3 domain protein)	Two-hybrid	BioGRID	16169070
LAMA4	DKFZp686D23145 \| LAMA3 \| LAMA4*-1	laminin, alpha 4	Two-hybrid	BioGRID	16169070
LCK	YT16 \| p56lck \| pp58lck	lymphocyte-specific protein tyrosine kinase	-	HPRD,BioGRID	14757743
LUC7L2	CGI-59 \| CGI-74 \| FLJ10657 \| LUC7B2	LUC7-like 2 (S. cerevisiae)	Two-hybrid	BioGRID	16169070
LYN	FLJ26625 \| JTK8	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	-	HPRD,BioGRID	12496276
MAPK10	FLJ12099 \| FLJ33785 \| JNK3 \| JNK3A \| MGC50974 \| PRKM10 \| p493F12 \| p54bSAPK	mitogen-activated protein kinase 10	Two-hybrid	BioGRID	16169070
MPHOSPH6	MPP \| MPP-6 \| MPP6	M-phase phosphoprotein 6	Two-hybrid	BioGRID	16169070
MRPS12	MPR-S12 \| MT-RPS12 \| RPMS12 \| RPS12 \| RPSM12	mitochondrial ribosomal protein S12	Two-hybrid	BioGRID	16169070
ORAI2	C7orf19 \| CBCIP2 \| FLJ12474 \| FLJ14733 \| FLJ44818 \| TMEM142B	ORAI calcium release-activated calcium modulator 2	Two-hybrid	BioGRID	16169070
PAFAH1B3	-	platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa	Two-hybrid	BioGRID	16169070
PAPSS1	ATPSK1 \| PAPSS \| SK1	3'-phosphoadenosine 5'-phosphosulfate synthase 1	Two-hybrid	BioGRID	16169070
PCDHA4	CNR1 \| CNRN1 \| CRNR1 \| MGC138307 \| MGC142169 \| PCDH-ALPHA4	protocadherin alpha 4	Two-hybrid	BioGRID	16169070
PFN1	-	profilin 1	Two-hybrid	BioGRID	16169070
PHF10	FLJ10975 \| MGC111009 \| XAP135	PHD finger protein 10	Two-hybrid	BioGRID	16169070
PPA1	IOPPP \| MGC111556 \| PP \| PP1 \| SID6-8061	pyrophosphatase (inorganic) 1	Two-hybrid	BioGRID	16169070
PPAP2C	LPP2 \| PAP-2c \| PAP2-g	phosphatidic acid phosphatase type 2C	Two-hybrid	BioGRID	16169070
PSMD11	MGC3844 \| Rpn6 \| S9 \| p44.5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	Two-hybrid	BioGRID	16169070
PSMD2	MGC14274 \| P97 \| Rpn1 \| S2 \| TRAP2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	Two-hybrid	BioGRID	16169070
PTPRS	PTPSIGMA	protein tyrosine phosphatase, receptor type, S	Two-hybrid	BioGRID	16169070
QTRT1	FP3235 \| TGT	queuine tRNA-ribosyltransferase 1	Two-hybrid	BioGRID	16169070
RFC5	MGC1155 \| RFC36	replication factor C (activator 1) 5, 36.5kDa	Two-hybrid	BioGRID	16169070
RGL2	HKE1.5 \| KE1.5 \| RAB2L	ral guanine nucleotide dissociation stimulator-like 2	Two-hybrid	BioGRID	16169070
RPA2	REPA2 \| RPA32	replication protein A2, 32kDa	Two-hybrid	BioGRID	16169070
RUFY3	KIAA0871 \| RIPX \| SINGAR1	RUN and FYVE domain containing 3	Two-hybrid	BioGRID	16169070
S100A4	18A2 \| 42A \| CAPL \| FSP1 \| MTS1 \| P9KA \| PEL98	S100 calcium binding protein A4	Two-hybrid	BioGRID	16169070
S100A8	60B8AG \| CAGA \| CFAG \| CGLA \| CP-10 \| L1Ag \| MA387 \| MIF \| MRP8 \| NIF \| P8	S100 calcium binding protein A8	Two-hybrid	BioGRID	16169070
SAT1	DC21 \| KFSD \| SAT \| SSAT \| SSAT-1	spermidine/spermine N1-acetyltransferase 1	Two-hybrid	BioGRID	16169070
SEPHS1	MGC4980 \| SELD \| SPS \| SPS1	selenophosphate synthetase 1	Two-hybrid	BioGRID	16169070
SERPINB9	CAP-3 \| CAP3 \| PI9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	Two-hybrid	BioGRID	16169070
SMN1	BCD541 \| SMA \| SMA1 \| SMA2 \| SMA3 \| SMA4 \| SMA@ \| SMN \| SMNT \| T-BCD541	survival of motor neuron 1, telomeric	Two-hybrid	BioGRID	16169070
SULT1E1	EST \| EST-1 \| MGC34459 \| STE	sulfotransferase family 1E, estrogen-preferring, member 1	Two-hybrid	BioGRID	16169070
TK1	TK2	thymidine kinase 1, soluble	Two-hybrid	BioGRID	16169070
TP53BP2	53BP2 \| ASPP2 \| BBP \| PPP1R13A \| p53BP2	tumor protein p53 binding protein, 2	Two-hybrid	BioGRID	16169070
TP53I3	PIG3	tumor protein p53 inducible protein 3	Two-hybrid	BioGRID	16169070
TRDMT1	DNMT2 \| M.HsaIIP \| PuMet \| RNMT1	tRNA aspartic acid methyltransferase 1	Two-hybrid	BioGRID	16169070
UBE2B	E2-17kDa \| HHR6B \| HR6B \| RAD6B \| UBC2	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	Two-hybrid	BioGRID	16169070
UBE2I	C358B7.1 \| P18 \| UBC9	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	Two-hybrid	BioGRID	16169070
UBQLN4	A1U \| C1orf6 \| CIP75 \| UBIN	ubiquilin 4	Two-hybrid	BioGRID	16169070
ZFP64	MGC940 \| ZNF338	zinc finger protein 64 homolog (mouse)	Two-hybrid	BioGRID	16169070
ZNF24	KOX17 \| RSG-A \| ZNF191 \| ZSCAN3 \| Zfp191	zinc finger protein 24	Two-hybrid	BioGRID	16169070

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
MULLIGHAN_MLL_SIGNATURE_1_UP	380	236	All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP	418	263	All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN	508	354	All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_UP	214	144	All SZGR genes in this pathway
PEREZ_TP53_TARGETS	1174	695	All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_VIA_SMAD4_DN	66	38	All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2	153	102	All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_17Q11_Q21_AMPLICON	133	78	All SZGR genes in this pathway
PENG_LEUCINE_DEPRIVATION_UP	142	93	All SZGR genes in this pathway
PENG_GLUCOSE_DEPRIVATION_UP	48	26	All SZGR genes in this pathway
SMITH_TERT_TARGETS_DN	87	69	All SZGR genes in this pathway
YAGI_AML_FAB_MARKERS	191	131	All SZGR genes in this pathway
BASSO_CD40_SIGNALING_UP	101	76	All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_UP	428	266	All SZGR genes in this pathway
BURTON_ADIPOGENESIS_6	189	112	All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P6	91	44	All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP	461	298	All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN	701	446	All SZGR genes in this pathway
MUELLER_PLURINET	299	189	All SZGR genes in this pathway
GOLDRATH_ANTIGEN_RESPONSE	346	192	All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_BRCA1_DN	44	28	All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2	491	319	All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_UP	72	53	All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP	857	456	All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP	211	131	All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP	281	183	All SZGR genes in this pathway
LIU_IL13_MEMORY_MODEL_UP	17	12	All SZGR genes in this pathway