Gene Page: USP2

Summary
GeneID  9099
Symbol  USP2
Synonyms  UBP41|USP9
Description  ubiquitin specific peptidase 2
See related  HGNC:12618|MIM:604725|Ensembl:ENSG00000036672|HPRD:05287|
Locus tag  -
Gene type  protein-coding
Map location  11q23.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI16189514 
GO:0004197cysteine-type endopeptidase activityTAS9827704 
GO:0004221ubiquitin thiolesterase activityIEA-
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006511ubiquitin-dependent protein catabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
GO:0005886plasma membraneIDA18029348 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BEGAINKIAA1446brain-enriched guanylate kinase-associated homolog (rat)Two-hybridBioGRID16189514 
BEND5C1orf165 | FLJ11588BEN domain containing 5Two-hybridBioGRID16189514 
CCDC85BDIPAcoiled-coil domain containing 85BTwo-hybridBioGRID16189514 
HOOK2FLJ26218 | HK2hook homolog 2 (Drosophila)Two-hybridBioGRID16189514 
KRT15CK15 | K15 | K1COkeratin 15Affinity Capture-Western
Two-hybrid		BioGRID16189514 
NFKB2LYT-10 | LYT10nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)Affinity Capture-MSBioGRID14743216 
TRAF2MGC:45012 | TRAP | TRAP3TNF receptor-associated factor 2Two-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN 384220All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN 284156All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN 291176All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM6 4632All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP 283177All SZGR genes in this pathway
UEDA_PERIFERAL_CLOCK 169111All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
MCCLUNG_DELTA_FOSB_TARGETS_8WK 4738All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_DN 14199All SZGR genes in this pathway
KUNINGER_IGF1_VS_PDGFB_TARGETS_UP 8251All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
XU_GH1_EXOGENOUS_TARGETS_DN 12069All SZGR genes in this pathway
DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2 11865All SZGR genes in this pathway
WILSON_PROTEASES_AT_TUMOR_BONE_INTERFACE_UP 2114All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5 3022All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN 505328All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-15/16/195/424/4974814871Ahsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-244604661Ahsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
miR-3314914981A,m8hsa-miR-331brainGCCCCUGGGCCUAUCCUAGAA
miR-5034804871A,m8hsa-miR-503UAGCAGCGGGAACAGUUCUGCAG
miR-504153159m8hsa-miR-504AGACCCUGGUCUGCACUCUAU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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