Gene Page: NRXN3

Summary
GeneID  9369
Symbol  NRXN3
Synonyms  KIAA0743|MGC176711
Description  neurexin 3
See related  HGNC:8010|MIM:600567|Ensembl:ENSG00000021645|HPRD:08989|
Locus tag  -
Gene type  protein-coding
Map location  14q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PADI20.780.80
ICAM10.770.71
KCNJ100.760.76
FOXF10.750.66
C5orf40.750.83
TJP20.740.76
KANK10.740.70
APOLD10.740.58
GPRC5B0.730.75
TPCN10.730.71
Top 10 negatively co-expressed genes
MED19-0.52-0.63
NKIRAS2-0.50-0.53
NR2C2AP-0.49-0.61
LSM7-0.49-0.68
DUSP12-0.49-0.57
PODXL2-0.49-0.54
ZNF821-0.48-0.54
TCTEX1D2-0.48-0.63
POLB-0.48-0.60
CCDC28B-0.48-0.66
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityTAS1621094 
GO:0005509calcium ion bindingIEA-
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007411axon guidanceTASaxon (GO term level: 13)1621094 
GO:0007155cell adhesionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA18029348 
GO:0005730nucleolusIDA18029348 
GO:0005737cytoplasmIDA18029348 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0005887integral to plasma membraneTAS1621094 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CASKCAGH39 | CMG | FLJ22219 | FLJ31914 | LIN2 | MICPCH | TNRC8calcium/calmodulin-dependent serine protein kinase (MAGUK family)-HPRD,BioGRID8786425 
MLLT4AF-6 | AF6 | AFADIN | FLJ34371 | RP3-431P23.3myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4-HPRD,BioGRID9707552 
NLGN1KIAA1070 | MGC45115neuroligin 1Reconstituted ComplexBioGRID8576240 
NLGN2KIAA1366neuroligin 2Reconstituted ComplexBioGRID8576240 
NLGN3ASPGX1 | AUTSX1 | HNL3 | KIAA1480neuroligin 3-HPRD,BioGRID8576240 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN 391222All SZGR genes in this pathway
CORRE_MULTIPLE_MYELOMA_UP 7445All SZGR genes in this pathway
RODRIGUES_NTN1_TARGETS_UP 1711All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_DN 232139All SZGR genes in this pathway
SENESE_HDAC2_TARGETS_DN 13377All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN 284156All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
CHEBOTAEV_GR_TARGETS_DN 12073All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_B 4822All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP 195138All SZGR genes in this pathway
LEE_TARGETS_OF_PTCH1_AND_SUFU_DN 8369All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL 254164All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
NIELSEN_SCHWANNOMA_UP 1816All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 307185All SZGR genes in this pathway
KONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3 9772All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_UP 170107All SZGR genes in this pathway
CAMPS_COLON_CANCER_COPY_NUMBER_DN 7434All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_UP 14175All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP 11370All SZGR genes in this pathway
CHICAS_RB1_TARGETS_GROWING 243155All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p147914851Ahsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-137243224381Ahsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-140111611221Ahsa-miR-140brainAGUGGUUUUACCCUAUGGUAG
miR-1836836891Ahsa-miR-183UAUGGCACUGGUAGAAUUCACUG
miR-214249255m8hsa-miR-214brainACAGCAGGCACAGACAGGCAG
miR-218263269m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-23149715041A,m8hsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-30-5p157515821A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-323149715031Ahsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-330771777m8hsa-miR-330brainGCAAAGCACACGGCCUGCAGAGA
miR-41022382244m8hsa-miR-410AAUAUAACACAGAUGGCCUGU
miR-488547553m8hsa-miR-488CCCAGAUAAUGGCACUCUCAA
miR-493-5p17161722m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-495223522411Ahsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
miR-4964484541Ahsa-miR-496AUUACAUGGCCAAUCUC
miR-542-3p152515311Ahsa-miR-542-3pUGUGACAGAUUGAUAACUGAAA
miR-54314471453m8hsa-miR-543AAACAUUCGCGGUGCACUUCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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