Gene Page: ARNT2

Summary
GeneID  9915
Symbol  ARNT2
Synonyms  KIAA0307|bHLHe1
Description  aryl-hydrocarbon receptor nuclear translocator 2
See related  HGNC:16876|MIM:606036|Ensembl:ENSG00000172379|
Locus tag  -
Gene type  protein-coding
Map location  15q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RP11-23D24.10.790.76
ANO60.780.81
ITPR20.760.80
PDLIM50.760.73
ITGA60.750.76
PCDHGC30.740.75
CDGAP0.740.76
LAMA40.730.73
RAB310.730.70
AP000872.10.720.80
Top 10 negatively co-expressed genes
TIMM10-0.34-0.34
A1BG-0.32-0.36
USMG5-0.31-0.29
C17orf61-0.31-0.32
DDTL-0.31-0.29
NDUFB1-0.31-0.26
MRPL21-0.31-0.37
BLOC1S1-0.30-0.29
NDUFA2-0.30-0.32
AL353354.3-0.30-0.15
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004871signal transducer activityIEA-
GO:0003700transcription factor activityISS-
GO:0017162aryl hydrocarbon receptor bindingISS-
GO:0046982protein heterodimerization activityIPI12239177 
GO:0046982protein heterodimerization activityISS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007417central nervous system developmentISSBrain (GO term level: 6)-
GO:0001666response to hypoxiaIDA12239177 
GO:0001701in utero embryonic developmentISS-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0007165signal transductionIEA-
GO:0045941positive regulation of transcriptionISS-
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA12239177 
GO:0005667transcription factor complexIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
NPAS4Le-PAS | NXF | PASD10neuronal PAS domain protein 4-HPRD,BioGRID14701734 
SIM2MGC119447 | SIM | bHLHe15single-minded homolog 2 (Drosophila)Two-hybridBioGRID14701734 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_RENAL_CELL_CARCINOMA 7060All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP 294178All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN 5036All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP 3823All SZGR genes in this pathway
RIZ_ERYTHROID_DIFFERENTIATION_12HR 4335All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL 326213All SZGR genes in this pathway
SILIGAN_BOUND_BY_EWS_FLT1_FUSION 4734All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_A 10063All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_DN 185111All SZGR genes in this pathway
FRASOR_RESPONSE_TO_ESTRADIOL_DN 8252All SZGR genes in this pathway
SASAKI_ADULT_T_CELL_LEUKEMIA 176122All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_LB_UP 4828All SZGR genes in this pathway
MCCLUNG_DELTA_FOSB_TARGETS_8WK 4738All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL 254164All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_DN 160101All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_4NQO_OR_UV 6344All SZGR genes in this pathway
KYNG_DNA_DAMAGE_UP 226164All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_LIVER_DN 109All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_UP 172109All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_UP 425253All SZGR genes in this pathway
ZHANG_TLX_TARGETS_36HR_UP 221150All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN 244157All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
BOSCO_TH1_CYTOTOXIC_MODULE 11462All SZGR genes in this pathway
DURAND_STROMA_NS_UP 162103All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-18141284134m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-34b41874193m8hsa-miR-34bUAGGCAGUGUCAUUAGCUGAUUG
miR-54341294135m8hsa-miR-543AAACAUUCGCGGUGCACUUCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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