Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 10 literature records

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Entrez IDDescription
1050may function as a tumor suppressor that is mutated during tumorigenesis. Abnormalties in C/EBPalpha function contribute to the development of malignancies in a variety of tisues.
2272"FHIT methylation was accumulated through the disease progression of MDS and AML, and the role of the FHIT gene as a tumor suppressor seemed different in AML and MDS"
11083Data suggest that Dido might be one of the tumor suppressor genes at chromosome 20q and that the Dido-targeted mouse may be a suitable model for studying myeloproliferative diseases and myelodysplastic syndromes.
4869Npm1 acts as a haploinsufficient tumor suppressor in the hematopoietic compartment
5728[Expression of tumor suppressor gene pten in patients with myelodysplastic syndrome and acute myeloid leukemia].
171023These findings suggest that ASXL1 may function as a tumor suppressor in malignancies of the myeloid lineage by affecting stem or progenitor cell self-renewal or differentiation.
54790"With diverse genetic methods, TET2 on chromosome 4q24 was identified as candidate tumor suppressor gene."
51523Lack of promoter hypermethylation or somatic mutations are found in the potential tumor suppressor CXXC5 in myelodysplastic syndromes or acute myeloid leukemia with deletion 5q.
58508this mouse model functionally validates MLL3 as a haploinsufficient 7q tumor suppressor and suggests a therapeutic option for this aggressive disease.
7503Xist RNA is a potent suppressor of hematologic cancer in mice.

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