Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

2810

Name

SFN

Synonymous

YWHAS;stratifin;SFN;stratifin

Definition

14-3-3 protein sigma|14-3-3 sigma|epithelial cell marker protein 1

Position

1p36.11

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction

   | Top |

Interaction Type

Interactor

Data Source

interacts with

MAGI1BIOGRID; PUBMED:15778465;

interacts with

MARK2BIOGRID; PUBMED:15778465;

interacts with

MARK3BIOGRID; PUBMED:15778465;

interacts with

MARK3BIOGRID; PUBMED:16189514;

interacts with

MLTKBIOGRID; PUBMED:15778465;

interacts with

MDM2BIOGRID; PUBMED:17546054;

interacts with

MAP3K2BIOGRID; PUBMED:15778465;

interacts with

MARK1BIOGRID; PUBMED:15778465;

interacts with

MPRIPBIOGRID; PUBMED:15778465;

interacts with

MDM4BIOGRID; PUBMED:16511560;

interacts with

TNK1BIOGRID; PUBMED:15778465;

interacts with

TBL3BIOGRID; PUBMED:16189514;

interacts with

TNS4BIOGRID; PUBMED:15778465;

interacts with

CDK1BIOGRID; PUBMED:10524633;

interacts with

WDYHV1BIOGRID; PUBMED:16189514;

interacts with

MYCBP2BIOGRID; PUBMED:15778465;

interacts with

NEDD4LBIOGRID; PUBMED:15778465;

interacts with

KLC1BIOGRID; PUBMED:15778465;

interacts with

KIF23BIOGRID; PUBMED:15778465;

interacts with

KIF5BBIOGRID; PUBMED:15778465;

interacts with

LMO7BIOGRID; PUBMED:15778465;

interacts with

LAD1BIOGRID; PUBMED:15778465;

interacts with

KLC2BIOGRID; PUBMED:15778465;

interacts with

PPFIBP1BIOGRID; PUBMED:15778465;

interacts with

KLHDC2BIOGRID; PUBMED:15778465;

interacts with

LSRBIOGRID; PUBMED:15778465;

interacts with

PPFIBP2BIOGRID; PUBMED:15778465;

interacts with

BADBIOGRID; PUBMED:16189514;

interacts with

ARHGEF17BIOGRID; PUBMED:15778465;

interacts with

ARHGEF16BIOGRID; PUBMED:15778465;

interacts with

BCAR1BIOGRID; PUBMED:15778465;

interacts with

ARAFBIOGRID; PUBMED:15778465;

interacts with

ARHGEF5BIOGRID; PUBMED:15778465;

interacts with

FAM189A2BIOGRID; PUBMED:16189514;

interacts with

ERRFI1BIOGRID; PUBMED:15778465;

interacts with

HDAC9BIOGRID; PUBMED:15166223;

interacts with

HDAC7BIOGRID; PUBMED:15778465;

interacts with

GPRIN2BIOGRID; PUBMED:16189514;

interacts with

GRB7BIOGRID; PUBMED:15778465;

interacts with

HNRNPUBIOGRID; PUBMED:15778465;

interacts with

HDAC4BIOGRID; PUBMED:15778465;

interacts with

GANBIOGRID; PUBMED:15778465;

interacts with

NR3C1BIOGRID; PUBMED:12730237;

interacts with

DYRK1ABIOGRID; PUBMED:15778465;

interacts with

DTX2BIOGRID; PUBMED:15778465;

interacts with

CSNK2A1BIOGRID; PUBMED:15778465;

interacts with

CYTH2BIOGRID; PUBMED:15778465;

interacts with

DCAF7BIOGRID; PUBMED:15778465;

interacts with

ING1BIOGRID; PUBMED:16581770;

interacts with

IRS2BIOGRID; PUBMED:15778465;

interacts with

KIAA0408BIOGRID; PUBMED:16189514;

interacts with

ARHGAP32BIOGRID; PUBMED:15778465;

interacts with

RALGPS2BIOGRID; PUBMED:15778465;

interacts with

RACGAP1BIOGRID; PUBMED:15778465;

interacts with

ITCHBIOGRID; PUBMED:15778465;

interacts with

RHPN2BIOGRID; PUBMED:15778465;

interacts with

ARHGAP11ABIOGRID; PUBMED:15778465;

interacts with

ARHGAP21BIOGRID; PUBMED:15778465;

interacts with

RAF1BIOGRID; PUBMED:15778465;

interacts with

JUBBIOGRID; PUBMED:15778465;

interacts with

RAE1BIOGRID; PUBMED:15778465;

interacts with

YWHAGBIOGRID; PUBMED:15778465;

interacts with

APLP2BIOGRID; PUBMED:15778465;

interacts with

ABLIM1BIOGRID; PUBMED:15778465;

interacts with

ANKS1ABIOGRID; PUBMED:15778465;

interacts with

APCBIOGRID; PUBMED:15778465;

interacts with

ISCUBIOGRID; PUBMED:15778465;

interacts with

PKP3BIOGRID; PUBMED:15778465;

interacts with

PPP1R3DBIOGRID; PUBMED:15778465;

interacts with

PTPN2BIOGRID; PUBMED:15778465;

interacts with

PLK4BIOGRID; PUBMED:16189514;

interacts with

PKP2BIOGRID; PUBMED:15778465;

interacts with

PKHD1BIOGRID; PUBMED:15778465;

interacts with

PLEKHF2BIOGRID; PUBMED:16189514;

interacts with

PTOV1BIOGRID; PUBMED:15778465;

interacts with

PI4KBBIOGRID; PUBMED:15778465;

interacts with

PTPN3BIOGRID; PUBMED:15778465;

interacts with

IRS1BIOGRID; PUBMED:15778465;

interacts with

TJP2BIOGRID; PUBMED:15778465;

interacts with

SYNJ2BIOGRID; PUBMED:15778465;

interacts with

SPIRE1BIOGRID; PUBMED:15778465;

interacts with

SORBS2BIOGRID; PUBMED:15778465;

interacts with

SRSF10BIOGRID; PUBMED:15778465;

interacts with

ST5BIOGRID; PUBMED:15778465;

interacts with

SRRM2BIOGRID; PUBMED:15778465;

interacts with

ZNF638BIOGRID; PUBMED:15778465;

interacts with

WEE1BIOGRID; PUBMED:15778465;

interacts with

USP8BIOGRID; PUBMED:15778465;

interacts with

TRIM32BIOGRID; PUBMED:15778465;

interacts with

TRIM25BIOGRID; PUBMED:12075357;

interacts with

SHCBP1BIOGRID; PUBMED:15778465;

interacts with

SAMSN1BIOGRID; PUBMED:20478393;

interacts with

SASH1BIOGRID; PUBMED:15778465;

interacts with

SH3BP4BIOGRID; PUBMED:15778465;

interacts with

SAV1BIOGRID; PUBMED:15778465;

interacts with

MAPKAP1BIOGRID; PUBMED:15778465;

interacts with

SH2D3ABIOGRID; PUBMED:15778465;

interacts with

SIPA1L3BIOGRID; PUBMED:15778465;

interacts with

SIPA1L1BIOGRID; PUBMED:15778465;

interacts with

SHROOM3BIOGRID; PUBMED:15778465;

interacts with

OSBPL3BIOGRID; PUBMED:15778465;

interacts with

TP53BIOGRID; PUBMED:11896572;

interacts with

TP53BIOGRID; PUBMED:14517281;

interacts with

TP53BIOGRID; PUBMED:17546054;

interacts with

PARD3BBIOGRID; PUBMED:15778465;

interacts with

PIK3C2BBIOGRID; PUBMED:15778465;

interacts with

PAK4BIOGRID; PUBMED:15778465;

interacts with

CHST1BIOGRID; PUBMED:16189514;

interacts with

CHEK1BIOGRID; PUBMED:11896572;

interacts with

CGNBIOGRID; PUBMED:15778465;

interacts with

MST1RCELL_MAP; PUBMED:12919677;

interacts with

MAP3K5HPRD; PUBMED:15023544;

interacts with

MARK3HPRD; PUBMED:16189514;

interacts with

CDC25BHPRD; PUBMED:15173315;

interacts with

MDM4HPRD; PUBMED:16511572;

interacts with

TBL3HPRD; PUBMED:16189514;

interacts with

WDYHV1HPRD; PUBMED:16189514;

interacts with

KCNK3HPRD; PUBMED:12433946;

interacts with

KCNK9HPRD; PUBMED:12433946;

interacts with

KCNK15HPRD; PUBMED:12433946;

interacts with

BAXHPRD; PUBMED:11574543;

interacts with

FAM189A2HPRD; PUBMED:16189514;

interacts with

EGFRHPRD; PUBMED:16799092;

interacts with

HDAC5HPRD; PUBMED:15367659;

interacts with

HNRNPDHPRD; PUBMED:16902409;

interacts with

GPRIN2HPRD; PUBMED:16189514;

interacts with

NR3C1HPRD; PUBMED:12730237;

interacts with

EEF1A1HPRD; PUBMED:17361185;

interacts with

ING1HPRD; PUBMED:16581770;

interacts with

EIF2S1HPRD; PUBMED:17361185;

interacts with

KIAA0408HPRD; PUBMED:16189514;

interacts with

MST1RHPRD; PUBMED:12919677;

interacts with

RFFLHPRD; PUBMED:18382127;

interacts with

YWHAGHPRD; PUBMED:15324660;

interacts with

EIF4BHPRD; PUBMED:17361185;

interacts with

PLK4HPRD; PUBMED:16189514;

interacts with

PLEKHF2HPRD; PUBMED:16189514;

interacts with

CCAR1HPRD; PUBMED:12816952;

interacts with

TRIM25HPRD; PUBMED:12075357;

interacts with

ZFP36HPRD; PUBMED:11886850;

interacts with

TSC2HPRD; PUBMED:12438239;

interacts with

CHST1HPRD; PUBMED:16189514;

interacts with

MDM1INTACT; PUBMED:21282530;

interacts with

MOV10INTACT; PUBMED:21282530;

interacts with

MKI67INTACT; PUBMED:21282530;

interacts with

KHDRBS2INTACT; PUBMED:21282530;

interacts with

ASAP1INTACT; PUBMED:21282530;

interacts with

BMI1INTACT; PUBMED:21282530;

interacts with

HIST1H1AINTACT; PUBMED:21282530;

interacts with

FERINTACT; PUBMED:21282530;

interacts with

ERCC6INTACT; PUBMED:21282530;

interacts with

CCDC158INTACT; PUBMED:21282530;

interacts with

CSNK2A1INTACT; PUBMED:21282530;

interacts with

CSNK2A2INTACT; PUBMED:21282530;

interacts with

CSNK2BINTACT; PUBMED:21282530;

interacts with

RNF17INTACT; PUBMED:21282530;

interacts with

RING1INTACT; PUBMED:21282530;

interacts with

RNF2INTACT; PUBMED:21282530;

interacts with

YWHAGINTACT; PUBMED:21282530;

interacts with

YWHABINTACT; PUBMED:21282530;

interacts with

YWHAZINTACT; PUBMED:21282530;

interacts with

YWHAEINTACT; PUBMED:21282530;

interacts with

YWHAHINTACT; PUBMED:21282530;

interacts with

YWHAQINTACT; PUBMED:21282530;

interacts with

SLC25A5INTACT; PUBMED:21282530;

interacts with

PHC3INTACT; PUBMED:21282530;

interacts with

PHC2INTACT; PUBMED:21282530;

interacts with

PHC1INTACT; PUBMED:21282530;

interacts with

SMC3INTACT; PUBMED:21282530;

interacts with

STAMBPL1INTACT; PUBMED:21282530;

interacts with

SMG1INTACT; PUBMED:21282530;

interacts with

SSX10INTACT; PUBMED:21282530;

interacts with

ZNF546INTACT; PUBMED:21282530;

interacts with

WDHD1INTACT; PUBMED:21282530;

interacts with

CENPFINTACT; PUBMED:21282530;

interacts with

RUVBL2INTACT; PUBMED:21282530;

interacts with

PCGF6INTACT; PUBMED:21282530;

interacts with

PCGF2INTACT; PUBMED:21282530;

interacts with

CHD7INTACT; PUBMED:21282530;

interacts with

MAGI1MINT; PUBMED:15778465;

interacts with

MARK2MINT; PUBMED:15778465;

interacts with

MARK3MINT; PUBMED:15778465;

interacts with

MARK3MINT; PUBMED:16189514;

interacts with

CDC25BMINT; PUBMED:15173315;

interacts with

CDC25BMINT; PUBMED:16672277;

interacts with

MLTKMINT; PUBMED:15778465;

interacts with

MDM2MINT; PUBMED:17546054;

interacts with

MAP3K2MINT; PUBMED:15778465;

interacts with

MARK1MINT; PUBMED:15778465;

interacts with

MPRIPMINT; PUBMED:15778465;

interacts with

MDM4MINT; PUBMED:16511572;

interacts with

CDC42BPGMINT; PUBMED:15778465;

interacts with

TNK1MINT; PUBMED:15778465;

interacts with

TPD52L1MINT; PUBMED:19732746;

interacts with

TBL3MINT; PUBMED:16189514;

interacts with

TNS4MINT; PUBMED:15778465;

interacts with

TUBA1CMINT; PUBMED:20618440;

interacts with

MYH9MINT; PUBMED:20618440;

interacts with

MYL3MINT; PUBMED:20618440;

interacts with

CDK1MINT; PUBMED:10524633;

interacts with

WDYHV1MINT; PUBMED:16189514;

interacts with

MYCBP2MINT; PUBMED:15778465;

interacts with

MYH13MINT; PUBMED:20618440;

interacts with

MYH7MINT; PUBMED:20618440;

interacts with

MYLK2MINT; PUBMED:20618440;

interacts with

KLC1MINT; PUBMED:15778465;

interacts with

KIF23MINT; PUBMED:15778465;

interacts with

KIF5BMINT; PUBMED:15778465;

interacts with

LMO7MINT; PUBMED:15778465;

interacts with

LAD1MINT; PUBMED:15778465;

interacts with

KLC2MINT; PUBMED:15778465;

interacts with

PPFIBP1MINT; PUBMED:15778465;

interacts with

KLHDC2MINT; PUBMED:15778465;

interacts with

PPFIBP2MINT; PUBMED:15778465;

interacts with

BADMINT; PUBMED:16189514;

interacts with

BADMINT; PUBMED:20005908;

interacts with

BADMINT; PUBMED:20179209;

interacts with

ARHGEF17MINT; PUBMED:15778465;

interacts with

ARHGEF16MINT; PUBMED:15778465;

interacts with

BAXMINT; PUBMED:11574543;

interacts with

BCAR1MINT; PUBMED:15778465;

interacts with

C1orf106MINT; PUBMED:15778465;

interacts with

ARAFMINT; PUBMED:15778465;

interacts with

ATP5A1MINT; PUBMED:20618440;

interacts with

ATP5BMINT; PUBMED:20618440;

interacts with

ARHGEF5MINT; PUBMED:15778465;

interacts with

ERRFI1MINT; PUBMED:15778465;

interacts with

EGFRMINT; PUBMED:19172738;

interacts with

HDAC5MINT; PUBMED:15923258;

interacts with

HIST1H2BDMINT; PUBMED:20618440;

interacts with

HDAC7MINT; PUBMED:15778465;

interacts with

HDAC7MINT; PUBMED:18339811;

interacts with

H1F0MINT; PUBMED:20618440;

interacts with

GPRIN2MINT; PUBMED:15778465;

interacts with

GPRIN2MINT; PUBMED:16189514;

interacts with

GRB7MINT; PUBMED:15778465;

interacts with

HMGCS2MINT; PUBMED:20618440;

interacts with

HNRNPUMINT; PUBMED:15778465;

interacts with

HDAC4MINT; PUBMED:15778465;

interacts with

HDAC4MINT; PUBMED:16767219;

interacts with

GAB2MINT; PUBMED:19172738;

interacts with

GANMINT; PUBMED:15778465;

interacts with

NR3C1MINT; PUBMED:12730237;

interacts with

FAM53BMINT; PUBMED:15778465;

interacts with

DYRK1AMINT; PUBMED:15778465;

interacts with

DTX2MINT; PUBMED:15778465;

interacts with

EEF1A1MINT; PUBMED:20618440;

interacts with

FAM117BMINT; PUBMED:15778465;

interacts with

EDC3MINT; PUBMED:15778465;

interacts with

CSNK2A1MINT; PUBMED:15778465;

interacts with

CYTH2MINT; PUBMED:15778465;

interacts with

DCAF7MINT; PUBMED:15778465;

interacts with

BadMINT; PUBMED:11697890;

interacts with

CBLMINT; PUBMED:11697890;

interacts with

KRT8MINT; PUBMED:20618440;

interacts with

ING1MINT; PUBMED:16581770;

interacts with

IRS2MINT; PUBMED:15778465;

interacts with

HSPB1MINT; PUBMED:20618440;

interacts with

KIAA0408MINT; PUBMED:16189514;

interacts with

KRT17MINT; PUBMED:20618440;

interacts with

RASSF1MINT; PUBMED:20069457;

interacts with

ARHGAP32MINT; PUBMED:15778465;

interacts with

REEP3MINT; PUBMED:15778465;

interacts with

RALGPS2MINT; PUBMED:15778465;

interacts with

RACGAP1MINT; PUBMED:15778465;

interacts with

ILDR2MINT; PUBMED:15778465;

interacts with

RHPN2MINT; PUBMED:15778465;

interacts with

ARHGAP11AMINT; PUBMED:15778465;

interacts with

ARHGAP21MINT; PUBMED:15778465;

interacts with

RAF1MINT; PUBMED:11697890;

interacts with

RAF1MINT; PUBMED:15778465;

interacts with

REEP4MINT; PUBMED:15778465;

interacts with

JUBMINT; PUBMED:15778465;

interacts with

RAE1MINT; PUBMED:15778465;

interacts with

RICTORMINT; PUBMED:15778465;

interacts with

YWHAGMINT; PUBMED:15778465;

interacts with

YWHAGMINT; PUBMED:19172738;

interacts with

YWHAGMINT; PUBMED:19860830;

interacts with

ANPEPMINT; PUBMED:20699358;

interacts with

PRKAR2AMINT; PUBMED:11414803;

interacts with

YWHABMINT; PUBMED:19172738;

interacts with

YWHABMINT; PUBMED:19860830;

interacts with

YWHABMINT; PUBMED:20618440;

interacts with

YWHAZMINT; PUBMED:15161933;

interacts with

YWHAZMINT; PUBMED:19172738;

interacts with

YWHAZMINT; PUBMED:19860830;

interacts with

YWHAZMINT; PUBMED:20618440;

interacts with

ACTBMINT; PUBMED:20618440;

interacts with

YWHAEMINT; PUBMED:19172738;

interacts with

YWHAEMINT; PUBMED:20618440;

interacts with

ACTA2MINT; PUBMED:20618440;

interacts with

ANKRD18AMINT; PUBMED:20618440;

interacts with

YWHAHMINT; PUBMED:19172738;

interacts with

YWHAHMINT; PUBMED:19860830;

interacts with

YWHAQMINT; PUBMED:19172738;

interacts with

YWHAQMINT; PUBMED:19860830;

interacts with

YWHAQMINT; PUBMED:20618440;

interacts with

ABLIM1MINT; PUBMED:15778465;

interacts with

AKT1MINT; PUBMED:20005908;

interacts with

ANKS1AMINT; PUBMED:15778465;

interacts with

APCMINT; PUBMED:15778465;

interacts with

KIAA0930MINT; PUBMED:15778465;

interacts with

ISCUMINT; PUBMED:15778465;

interacts with

PRKDCMINT; PUBMED:20618440;

interacts with

PKP3MINT; PUBMED:15778465;

interacts with

PPP1R3DMINT; PUBMED:15778465;

interacts with

PTPN2MINT; PUBMED:15778465;

interacts with

PLK4MINT; PUBMED:16189514;

interacts with

PKP2MINT; PUBMED:15778465;

interacts with

PLEKHF2MINT; PUBMED:16189514;

interacts with

PTOV1MINT; PUBMED:15778465;

interacts with

PI4KBMINT; PUBMED:15778465;

interacts with

PTPN3MINT; PUBMED:15778465;

interacts with

IRS1MINT; PUBMED:15778465;

interacts with

TJP2MINT; PUBMED:15778465;

interacts with

SYNJ2MINT; PUBMED:15778465;

interacts with

SPIRE1MINT; PUBMED:15778465;

interacts with

SORBS2MINT; PUBMED:15778465;

interacts with

SAMD4AMINT; PUBMED:15778465;

interacts with

SRSF10MINT; PUBMED:15778465;

interacts with

ST5MINT; PUBMED:15778465;

interacts with

TUT1MINT; PUBMED:20618440;

interacts with

SRRM2MINT; PUBMED:15778465;

interacts with

ZNF638MINT; PUBMED:15778465;

interacts with

WNK4MINT; PUBMED:20618440;

interacts with

WEE1MINT; PUBMED:15778465;

interacts with

USP43MINT; PUBMED:15778465;

interacts with

USP8MINT; PUBMED:15778465;

interacts with

TRIM32MINT; PUBMED:15778465;

interacts with

WDR37MINT; PUBMED:15778465;

interacts with

TSC2MINT; PUBMED:12438239;

interacts with

SCELMINT; PUBMED:15778465;

interacts with

SHCBP1MINT; PUBMED:15778465;

interacts with

SGK223MINT; PUBMED:15778465;

interacts with

SASH1MINT; PUBMED:15778465;

interacts with

SH3BP4MINT; PUBMED:15778465;

interacts with

SAV1MINT; PUBMED:15778465;

interacts with

SHROOM1MINT; PUBMED:15778465;

interacts with

MAPKAP1MINT; PUBMED:15778465;

interacts with

SH2D3AMINT; PUBMED:15778465;

interacts with

SIPA1L3MINT; PUBMED:15778465;

interacts with

CCDC101MINT; PUBMED:15778465;

interacts with

SIPA1L1MINT; PUBMED:15778465;

interacts with

SHROOM3MINT; PUBMED:15778465;

interacts with

OSBPL3MINT; PUBMED:15778465;

interacts with

PACS2MINT; PUBMED:15778465;

interacts with

TP53MINT; PUBMED:20206173;

interacts with

PARD3BMINT; PUBMED:15778465;

interacts with

PDZD11MINT; PUBMED:15778465;

interacts with

PIK3C2BMINT; PUBMED:15778465;

interacts with

PAK4MINT; PUBMED:15778465;

interacts with

CHST1MINT; PUBMED:16189514;

interacts with

CPS1MINT; PUBMED:20618440;

interacts with

CGNMINT; PUBMED:15778465;

Metabolic Interaction

   | Top |

Interaction Type

Interactor

Data Source

metabolic catalysis

ZNF385ANCI_NATURE; PUBMED:17719541;PUBMED:9659898;

metabolic catalysis

TP53NCI_NATURE; PUBMED:17719541;PUBMED:9659898;

Signaling Interaction

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Interaction Type

Interactor

Data Source

reacts with

HSP90AA1NCI_NATURE; PUBMED:12730237;

reacts with

FKBP5NCI_NATURE; PUBMED:12730237;

reacts with

SFNNCI_NATURE; PUBMED:12730237;


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