Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10039668HBVENSG00000055118.18protein_codingKCNH2NoNo3757A0A090N7W1
A0A090N7X5
A0A090N8Q0
Q12809
TCGA Plot Options
Drug Information
GeneKCNH2
DrugBank IDDB01026
Drug NameKetoconazole
Target IDBE0000090
UniProt IDQ12809
Regulation Typeinhibitor
PubMed IDs15272206
CitationsChiu PJ, Marcoe KF, Bounds SE, Lin CH, Feng JJ, Lin A, Cheng FC, Crumb WJ, Mitchell R: Validation of a [3H]astemizole binding assay in HEK293 cells expressing HERG K+ channels. J Pharmacol Sci. 2004 Jul;95(3):311-9.
GroupsApproved; Investigational
Direct ClassificationPhenylpiperazines
SMILESCC(=O)N1CCN(CC1)C1=CC=C(OCC2COC(CN3C=CN=C3)(O2)C2=CC=C(Cl)C=C2Cl)C=C1
Pathways
PharmGKBPA450146
ChEMBLCHEMBL157101