| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10039668 | HBV | ENSG00000055118.18 | protein_coding | KCNH2 | No | No | 3757 | A0A090N7W1 A0A090N7X5 A0A090N8Q0 Q12809 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNH2 |
|---|---|
| DrugBank ID | DB00276 |
| Drug Name | Amsacrine |
| Target ID | BE0000090 |
| UniProt ID | Q12809 |
| Regulation Type | inhibitor |
| PubMed IDs | 15148258 |
| Citations | Thomas D, Hammerling BC, Wu K, Wimmer AB, Ficker EK, Kirsch GE, Kochan MC, Wible BA, Scholz EP, Zitron E, Kathofer S, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J: Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action. Br J Pharmacol. 2004 Jun;142(3):485-94. Epub 2004 May 17. |
| Groups | Approved; Investigational |
| Direct Classification | Acridines |
| SMILES | COC1=C(NC2=C3C=CC=CC3=NC3=CC=CC=C23)C=CC(NS(C)(=O)=O)=C1 |
| Pathways | |
| PharmGKB | PA10309 |
| ChEMBL | CHEMBL43 |
