Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10039668HBVENSG00000055118.18protein_codingKCNH2NoNo3757A0A090N7W1
A0A090N7X5
A0A090N8Q0
Q12809
TCGA Plot Options
Drug Information
GeneKCNH2
DrugBank IDDB04855
Drug NameDronedarone
Target IDBE0000090
UniProt IDQ12809
Regulation Typeinhibitor
PubMed IDs17896959; 23997577
CitationsIwamoto T, Watanabe Y, Kita S, Blaustein MP: Na+/Ca2+ exchange inhibitors: a new class of calcium regulators. Cardiovasc Hematol Disord Drug Targets. 2007 Sep;7(3):188-98.@@Heijman J, Heusch G, Dobrev D: Pleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillation. Clin Med Insights Cardiol. 2013 Aug 11;7:127-40. doi: 10.4137/CMC.S8445. eCollection 2013.
GroupsApproved
Direct ClassificationAryl-phenylketones
SMILESCCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C1=C(CCCC)OC2=C1C=C(NS(C)(=O)=O)C=C2
Pathways
PharmGKBPA153619853
ChEMBLCHEMBL184412