VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS10039668 | HBV | ENSG00000055118.18 | protein_coding | KCNH2 | No | No | 3757 | A0A090N7W1 A0A090N7X5 A0A090N8Q0 Q12809 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | KCNH2 |
---|---|
DrugBank ID | DB01182 |
Drug Name | Propafenone |
Target ID | BE0000090 |
UniProt ID | Q12809 |
Regulation Type | inhibitor |
PubMed IDs | 11330342; 12618228; 11752352 |
Citations | Mergenthaler J, Haverkamp W, Huttenhofer A, Skryabin BV, Musshoff U, Borggrefe M, Speckmann EJ, Breithardt G, Madeja M: Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel. Naunyn Schmiedebergs Arch Pharmacol. 2001 Apr;363(4):472-80.@@Arias C, Gonzalez T, Moreno I, Caballero R, Delpon E, Tamargo J, Valenzuela C: Effects of propafenone and its main metabolite, 5-hydroxypropafenone, on HERG channels. Cardiovasc Res. 2003 Mar;57(3):660-9.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
Groups | Approved |
Direct Classification | Linear 1,3-diarylpropanoids |
SMILES | CCCNCC(O)COC1=C(C=CC=C1)C(=O)CCC1=CC=CC=C1 |
Pathways | |
PharmGKB | PA451131 |
ChEMBL | CHEMBL631 |