Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10039668HBVENSG00000055118.18protein_codingKCNH2NoNo3757A0A090N7W1
A0A090N7X5
A0A090N8Q0
Q12809
TCGA Plot Options
Drug Information
GeneKCNH2
DrugBank IDDB01074
Drug NamePerhexiline
Target IDBE0000090
UniProt IDQ12809
Regulation Type
PubMed IDs18701618
CitationsPerrin MJ, Kuchel PW, Campbell TJ, Vandenberg JI: Drug binding to the inactivated state is necessary but not sufficient for high-affinity binding to human ether-a-go-go-related gene channels. Mol Pharmacol. 2008 Nov;74(5):1443-52. doi: 10.1124/mol.108.049056. Epub 2008 Aug 13.
GroupsApproved; Investigational
Direct ClassificationPiperidines
SMILESC(C(C1CCCCC1)C1CCCCC1)C1CCCCN1
Pathways
PharmGKBPA130150436
ChEMBLCHEMBL75880