Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10039668HBVENSG00000055118.18protein_codingKCNH2NoNo3757A0A090N7W1
A0A090N7X5
A0A090N8Q0
Q12809
TCGA Plot Options
Drug Information
GeneKCNH2
DrugBank IDDB06457
Drug NameTecastemizole
Target IDBE0000090
UniProt IDQ12809
Regulation Type
PubMed IDs10376921
CitationsZhou Z, Vorperian VR, Gong Q, Zhang S, January CT: Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole. J Cardiovasc Electrophysiol. 1999 Jun;10(6):836-43.
GroupsInvestigational
Direct ClassificationBenzimidazoles
SMILESFC1=CC=C(CN2C(NC3CCNCC3)=NC3=CC=CC=C23)C=C1
Pathways
PharmGKB
ChEMBLCHEMBL61301