Gene: ZGRF1

55345
C4orf21
zinc finger GRF-type containing 1
protein-coding
4q25
Ensembl:ENSG00000138658 Vega:OTTHUMG00000132908 UniprotKB:Q86YA3
NG_053121.1
SNP Mapped
7   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.389e-1 (AD)  3.583e-2 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs13146963chr4:112637446 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)
rs2087111chr4:112614924 (GRCh38.p7)A>G / A>Talcohol dependenceSNV(Single Nucleotide Variation)
rs9307383chr4:112608678 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)
rs2029211chr4:112566978 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)
rs9991830chr4:112564216 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)
rs4833414chr4:112548757 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)
rs1486865chr4:112544495 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZGRF1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZGRF1 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of ZGRF1 mRNA22230336
D020106AcrylamideAcrylamide results in increased expression of ZGRF1 mRNA28959563
D001280AtrazineAtrazine results in increased expression of ZGRF1 mRNA27614199
C006780bisphenol Abisphenol A results in decreased expression of ZGRF1 mRNA29275510
C006780bisphenol Abisphenol A results in increased expression of ZGRF1 mRNA26063408
C006780bisphenol Abisphenol A results in decreased expression of ZGRF1 mRNA25181051
C018475butyraldehydebutyraldehyde results in decreased expression of ZGRF1 mRNA26079696
D004041Dietary FatsDietary Fats results in increased expression of ZGRF1 mRNA25016146
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of ZGRF1 mRNA27614199
D002117CalcitriolCalcitriol results in decreased expression of ZGRF1 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in decreased expression of ZGRF1 mRNA21592394
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of ZGRF1 mRNA23649840
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ZGRF1 mRNA25613284
D007840LatexLatex analog results in increased expression of ZGRF1 mRNA24768652
D007854LeadLead affects the expression of ZGRF1 mRNA28903495
C030272maleic acidmaleic acid results in decreased expression of ZGRF1 mRNA28392987
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ZGRF1 mRNA23649840
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZGRF1 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of ZGRF1 mRNA26272509
D010936Plant ExtractsPlant Extracts results in increased expression of ZGRF1 mRNA23557933
C005556propionaldehydepropionaldehyde results in decreased expression of ZGRF1 mRNA26079696
D000952Antigens, Polyomavirus Transforming"Antigens, Polyomavirus Transforming results in increased expression of ZGRF1 mRNA"26680231
D013739Testosterone[Testosterone co-treated with Calcitriol] results in decreased expression of ZGRF1 mRNA21592394
D013739TestosteroneTestosterone results in decreased expression of ZGRF1 mRNA21592394
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ZGRF1 mRNA25613284
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of ZGRF1 mRNA"26179874
D014635Valproic AcidValproic Acid results in decreased expression of ZGRF1 mRNA23179753|2718838
D014635Valproic AcidValproic Acid results in increased expression of ZGRF1 mRNA28001369

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-IBA21873635  
GO:0008270zinc ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal