Gene: SNX29

92017
A-388D4.1|RUNDC2A
sorting nexin 29
protein-coding
16p13.13-p13.12
Ensembl:ENSG00000048471 Vega:OTTHUMG00000129827 UniprotKB:Q8TEQ0
NC_000016.10
SNP Mapped
3   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.155e-1 (AD)  3.166e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs350255chr16:12111685 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)
rs183008chr16:12107834 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)
rs350212chr16:12060521 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FNBP10.84
KIF16B0.824
CDK5RAP20.821
DST0.817
ATXN1L0.813
ENTPD50.811
FMNL20.81
RDX0.808
C22orf230.804
RFFL0.796

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.48
OR4F5-0.441
PNOC-0.27
EPPIN-0.27
SULT2B1-0.262
PRTN3-0.257
CRH-0.251
NPW-0.238
PRSS56-0.226
DPYS-0.224

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of SNX29 mRNA"25510870
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SNX29 mRNA"19167446
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of SNX29 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of SNX29 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of SNX29 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of SNX29 mRNA"25510870
D000082AcetaminophenAcetaminophen results in increased expression of SNX29 mRNA29067470
D016604Aflatoxin B1Aflatoxin B1 affects the expression of SNX29 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of SNX29 mRNA21641981
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of SNX29 gene27153756
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of SNX29 mRNA20064835|2010694
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SNX29 mRNA"26238291
C006780bisphenol Abisphenol A results in increased expression of SNX29 mRNA29275510
C006780bisphenol Abisphenol A affects the expression of SNX29 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of SNX29 gene28505145
C018475butyraldehydebutyraldehyde results in decreased expression of SNX29 mRNA26079696
D002273CarcinogensCarcinogens results in decreased expression of SNX29 mRNA22269147
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of SNX29 mRNA28472532
D003300CopperCopper deficiency results in increased expression of SNX29 mRNA26033743
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SNX29 mRNA"19167446
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of SNX29 mRNA28962523
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of SNX29 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of SNX29 mRNA27392435|2759478
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of SNX29 mRNA19850644
D004051Diethylhexyl PhthalatePPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SNX29 mRNA]19850644
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SNX29 mRNA22079256
D000431EthanolEthanol results in decreased expression of SNX29 mRNA19167417
C024565ethylene dichlorideethylene dichloride results in decreased expression of SNX29 mRNA28189721
C039281furanfuran results in decreased expression of SNX29 mRNA25539665
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SNX29 mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of SNX29 mRNA27392435
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of SNX29 mRNA25890327
D008558MelphalanMelphalan results in decreased expression of SNX29 mRNA22363485
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of SNX29 mRNA26011545
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of SNX29 mRNA23649840
D009153MutagensMutagens results in decreased expression of SNX29 mRNA22269147
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of SNX29 mRNA"28673683
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of SNX29 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of SNX29 mRNA"25554681
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of SNX29 mRNA"25510870
D010936Plant ExtractsPlant Extracts results in increased expression of SNX29 mRNA23557933
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SNX29 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of SNX29 mRNA22079256
C017947sodium arsenitesodium arsenite results in increased expression of SNX29 mRNA22714537
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SNX29 mRNA25613284
C012589trichostatin Atrichostatin A affects the expression of SNX29 mRNA28542535
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of SNX29 mRNA19042947
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of SNX29 mRNA"26179874
D014520UrethaneUrethane results in increased expression of SNX29 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of SNX29 mRNA17963808
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of SNX29 gene25560391
C029297vinylidene chloridevinylidene chloride results in decreased expression of SNX29 mRNA26682919

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0035091phosphatidylinositol binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal