DegronMD

Uniprot ID: Q86SG3

Source protein: Deleted in azoospermia protein 4

Source gene: DAZ4

Class: DEG_SCF_FBW7_1

Location: 171:177

E3 ligase: FBXW7

DEGRON score: 0.8318

ASA_SCORE: 63.3714

COIL: 0.843

CONS_SCORE: 0.2014

DSS_SCORE: 0.7007

HELIX: 0.0733

FCONS_SCORE: 0.8256

RIG_SCORE: 0.6287

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Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9NQZ3	Deleted in azoospermia protein 1	DEG_SCF_FBW7_1	6:12	PETPNST	FBXW7	0.7887	More...
Q9NQZ3	Deleted in azoospermia protein 1	DEG_SCF_FBW7_1	171:177	PETPNST	FBXW7	0.624	More...
Q9NQZ3	Deleted in azoospermia protein 1	DEG_SCF_FBW7_1	336:342	PETPNST	FBXW7	0.9674	More...
Q13117	Deleted in azoospermia protein 2	DEG_SCF_FBW7_1	6:12	PETPNST	FBXW7	0.6326	More...
Q9NR90	Deleted in azoospermia protein 3	DEG_SCF_FBW7_1	6:12	PETPNST	FBXW7	0.9335	More...
Q86SG3	Deleted in azoospermia protein 4	DEG_SCF_FBW7_1	6:12	PETPNST	FBXW7	0.6326	More...
Q86SG3	Deleted in azoospermia protein 4	DEG_SCF_FBW7_1	171:177	PETPNST	FBXW7	0.8318	More...
Q92904	Deleted in azoospermia-like	DEG_SCF_FBW7_1	6:12	PETPNST	FBXW7	0.9473	More...

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DegronMD: protein-targeted degradation, mutation and drug response to degrons