DegronMD

Uniprot ID: Q08211

Source protein: ATP-dependent RNA helicase A

Source gene: DHX9

Class: DEG_SPOP_SBC_1

Location: 341:345

E3 ligase: SPOP

DEGRON score: 0.9938

ASA_SCORE: 70.32

COIL: 0.8154

CONS_SCORE: 0.3625

DSS_SCORE: 0.579

HELIX: 0.1384

FCONS_SCORE: 0.8927

RIG_SCORE: 0.7109

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P334H	TCGA-EB-A44R	SKCM	TCGA	PWTSS	DEG_SPOP_SBC_1	0.1389
p.P334H	DO37754	SKCM	ICGC	PWTSS	DEG_SPOP_SBC_1	0.1389
p.S345I	DO229027	LICA	ICGC	PWTSS	DEG_SPOP_SBC_1	0.7341
p.N338S	DO50949	LICA	ICGC	PWTSS	DEG_SPOP_SBC_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P40200	T-cell surface protein tactile	DEG_SPOP_SBC_1	446:450	PWTSS	SPOP	0.6584	More...
Q08211	ATP-dependent RNA helicase A	DEG_SPOP_SBC_1	341:345	PWTSS	SPOP	0.9938	More...
Q9NWQ4	G patch domain-containing protein 2-like	DEG_SPOP_SBC_1	176:180	PWTSS	SPOP	0.7902	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons