DegronMD

Uniprot ID: P49918

Source protein: Cyclin-dependent kinase inhibitor 1C

Source gene: CDKN1C

Class: DEG_APCC_TPR_1

Location: 314:316

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9942

ASA_SCORE: 149.2

COIL: 0.8447

CONS_SCORE: 0.7674

DSS_SCORE: 0.9692

HELIX: 0.1267

FCONS_SCORE: 1.0921

RIG_SCORE: 0.7308

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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P49918	Cyclin-dependent kinase inhibitor 1C	DEG_APCC_TPR_1	314:316	RLR	APC,CDC20,FZR1	0.9942	More...
Q86Y38	Xylosyltransferase 1	DEG_APCC_TPR_1	957:959	RLR	APC,CDC20,FZR1	0.9261	More...
Q9H1B5	Xylosyltransferase 2	DEG_APCC_TPR_1	863:865	RLR	APC,CDC20,FZR1	0.7158	More...

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DegronMD: protein-targeted degradation, mutation and drug response to degrons