DegronMD

Uniprot ID: Q96HA1

Source protein: Nuclear envelope pore membrane protein POM 121

Source gene: POM121

Class: DEG_SCF_FBW7_1

Location: 1115:1121

E3 ligase: FBXW7

DEGRON score: 0.991

ASA_SCORE: 76.1571

COIL: 0.9554

CONS_SCORE: 0.5294

DSS_SCORE: 0.3882

HELIX: 0.0126

FCONS_SCORE: 0.8302

RIG_SCORE: 0.6853

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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96HA1	Nuclear envelope pore membrane protein POM 121	DEG_SCF_FBW7_1	1115:1121	VATPGSS	FBXW7	0.991	More...
A8CG34	Nuclear envelope pore membrane protein POM 121C	DEG_SCF_FBW7_1	1095:1101	VATPGSS	FBXW7	0.9889	More...
A6NF01	Putative nuclear envelope pore membrane protein POM 121B	DEG_SCF_FBW7_1	700:706	VATPGSS	FBXW7	0.9919	More...

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DegronMD: protein-targeted degradation, mutation and drug response to degrons