DegronMD

Uniprot ID: Q5QGS0

Source protein: Neurite extension and migration factor

Source gene: NEXMIF

Class: DEG_APCC_KENBOX_2

Location: 23:27

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.8948

ASA_SCORE: 86.4

COIL: 0.7024

CONS_SCORE: 0.4663

DSS_SCORE: 0.5481

HELIX: 0.0464

FCONS_SCORE: 1.1685

RIG_SCORE: 0.7081

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D27Y	SIDM01254	Burkitt's Lymphoma	GDSC	VKEND	DEG_APCC_KENBOX_2	0.6214

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P46778	60S ribosomal protein L21	DEG_APCC_KENBOX_2	109:113	VKEND	APC,CDC20,FZR1	0.5218	More...
Q5QGS0	Neurite extension and migration factor	DEG_APCC_KENBOX_2	23:27	VKEND	APC,CDC20,FZR1	0.8948	More...
Q6P587	Acylpyruvase FAHD1, mitochondrial	DEG_APCC_KENBOX_2	199:203	VKEND	APC,CDC20,FZR1	0.6039	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons