DegronMD

Uniprot ID: A6NFA0

Source protein: Protein FAM205C

Source gene: FAM205C

Class: DEG_SCF_FBW7_1

Location: 168:173

E3 ligase: FBXW7

DEGRON score: 0.8082

ASA_SCORE: 69.3833

COIL: 0.7367

CONS_SCORE: 0.498

DSS_SCORE: 0.4304

HELIX: 0.2188

FCONS_SCORE: 0.8212

RIG_SCORE: 0.749

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P158L	SIDM00945	Colorectal Carcinoma	GDSC	VTPTLS	DEG_SCF_FBW7_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8IWV1	Lymphocyte transmembrane adapter 1	DEG_SCF_FBW7_1	4:9	VTPTLS	FBXW7	0.5009	More...
A6NFA0	Protein FAM205C	DEG_SCF_FBW7_1	168:173	VTPTLS	FBXW7	0.8082	More...
Q6ZU69	Protein FAM205A	DEG_SCF_FBW7_1	168:173	VTPTLS	FBXW7	0.9955	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons