DegronMD - A7KAX9(ARHGAP32)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R1387L	TCGA-28-5211	GBM	TCGA	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.25
p.R1206L	TCGA-55-8507	LUAD	TCGA	PPSY	ITCH	1213:1216	Mutation rewiring degron network	0.1389
p.R1398L	TCGA-78-8662	LUAD	TCGA	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation altering degron motif	0.7316
p.R1206C	TCGA-86-A4JF	LUAD	TCGA	PPSY	ITCH	1213:1216	Mutation rewiring degron network	0.1389
p.N740S	TCGA-93-A4JQ	LUAD	TCGA	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation rewiring degron network	0.1111
p.R1391Q	TCGA-A4-8098	KIRP	TCGA	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation altering degron motif	0.7329
p.V45A	TCGA-AA-3815	COAD	TCGA	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation altering degron motif	0.6936
p.V45A	DO9924	COAD	ICGC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation altering degron motif	0.6936
p.F1207L	TCGA-AP-A056	UCEC	TCGA	PPSY	ITCH	1213:1216	Mutation rewiring degron network	0.1667
p.A1425T	TCGA-AP-A059	UCEC	TCGA	ATSSS	DEG_SPOP_SBC_1	1434:1438	Mutation rewiring degron network	0.0833
p.P1403S	TCGA-B5-A11E	UCEC	TCGA	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.1944
p.A1404V	TCGA-B5-A1MX	UCEC	TCGA	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.1667
p.S736C	TCGA-BH-A0HP	BRCA	TCGA	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation blocking phosphorylation signal	0.6667
p.R1398C	TCGA-BR-4292	STAD	TCGA	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation altering degron motif	0.719
p.R1398C	SIDM00498	Colorectal Carcinoma	GDSC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation altering degron motif	0.719
p.R1398C	SNU-C5	large intestine	COSMIC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation altering degron motif	0.719
p.K721R	TCGA-BR-7704	STAD	TCGA	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation substituting flanking lysine	0.25
p.R1645Q	TCGA-CK-5913	COAD	TCGA	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.1389
p.R1645Q	TCGA-CK-5913	COAD	TCGA	LQPYFE	LIG_APCC_ABBA_1	1637:1642	Mutation rewiring degron network	0.25
p.L1395P	TCGA-CM-6674	COAD	TCGA	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation altering degron motif	0.6471
p.S1220N	TCGA-DF-A2KU	UCEC	TCGA	PPSY	ITCH	1213:1216	Mutation blocking phosphorylation signal	0.6667
p.V943I	TCGA-EA-A410	CESC	TCGA	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.1944
p.R63Q	TCGA-EI-6917	READ	TCGA	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.1389
p.R63Q	DO36881	READ	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.1389
p.P62H	TCGA-EL-A3T9	THCA	TCGA	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.1667
p.P62H	DO39635	THCA	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.1667
p.V1221A	TCGA-EO-A22R	UCEC	TCGA	PPSY	ITCH	1213:1216	Mutation rewiring degron network	0.1944
p.R1629S	TCGA-ER-A2NG	SKCM	TCGA	LQPYFE	LIG_APCC_ABBA_1	1637:1642	Mutation rewiring degron network	0.1111
p.R729I	TCGA-GN-A266	SKCM	TCGA	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation altering degron motif	0.6991
p.R1645W	TCGA-HU-A4GP	STAD	TCGA	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.1389
p.R1645W	TCGA-HU-A4GP	STAD	TCGA	LQPYFE	LIG_APCC_ABBA_1	1637:1642	Mutation rewiring degron network	0.25
p.S927L	TCGA-LB-A7SX	PAAD	TCGA	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.1389
p.A1390T	TCGA-NI-A8LF	LIHC	TCGA	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation altering degron motif	0.6028
p.R65W	TCGA-SX-A71V	KIRP	TCGA	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.0833
p.R65W	DO49780	KIRP	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.0833
p.S1657C	TCGA-VS-A9UC	CESC	TCGA	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.3056
p.P1406L	TCGA-W3-A825	SKCM	TCGA	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.1111
p.D1385N	DO219049	BLCA	ICGC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation substituting flanking lysine	0.3056
p.S1653C	DO219014	BLCA	ICGC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation altering degron motif	0.7541
p.E1459K	DO477	BLCA	ICGC	ASSTS	DEG_SPOP_SBC_1	1446:1450	Mutation rewiring degron network	0.0833
p.G1662V	DO767	BLCA	ICGC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.1667
p.E1635D	DO225278	BRCA	ICGC	LQPYFE	LIG_APCC_ABBA_1	1637:1642	Mutation blocking phosphorylation signal	0.7222
p.S1392L	DO1088	BRCA	ICGC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation altering degron motif	0.7667
p.R1402C	DO230335	COCA	ICGC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.2222
p.N722Y	DO227668	COCA	ICGC	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation rewiring degron network	0.1667
p.Y1401F	DO234171	ESAD	ICGC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation blocking phosphorylation signal	0.6944
p.R63L	DO233936	GACA	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.1389
p.E1223K	DO12196	GBM	ICGC	PPSY	ITCH	1213:1216	Mutation substituting flanking lysine	0.25
p.E1223K	DO26420	LUSC	ICGC	PPSY	ITCH	1213:1216	Mutation substituting flanking lysine	0.25
p.E1223K	DO40884	UCEC	ICGC	PPSY	ITCH	1213:1216	Mutation substituting flanking lysine	0.25
p.E1223K	DO50075	UCEC	ICGC	PPSY	ITCH	1213:1216	Mutation substituting flanking lysine	0.25
p.D1434E	DO229029	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	1434:1438	Mutation altering degron motif	0.6758
p.Q1657K	DO229029	LICA	ICGC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.3056
p.Q1657K	DO229027	LICA	ICGC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.3056
p.P942S	DO229052	LICA	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.2222
p.G51D	DO50861	LICA	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation altering degron motif	0.7198
p.H1638R	DO45005	LIHC	ICGC	LQPYFE	LIG_APCC_ABBA_1	1637:1642	Mutation altering degron motif	0.8244
p.S1666R	DO25104	LUAD	ICGC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.0556
p.G1436R	DO45340	LUAD	ICGC	ATSSS	DEG_SPOP_SBC_1	1434:1438	Mutation altering degron motif	0.7568
p.G1450W	DO24900	LUAD	ICGC	ASSTS	DEG_SPOP_SBC_1	1446:1450	Mutation altering degron motif	0.7825
p.M1398I	DO23624	LUAD	ICGC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation altering degron motif	0.7618
p.G719V	DO51193	LUAD	ICGC	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation rewiring degron network	0.0833
p.G719V	ACH-000684	Kidney Cancer	CCLE	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation rewiring degron network	0.0833
p.G719V	KMRC-1	kidney	COSMIC	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation rewiring degron network	0.0833
p.D1651N	DO26444	LUSC	ICGC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.3056
p.D1651N	DO26444	LUSC	ICGC	LQPYFE	LIG_APCC_ABBA_1	1637:1642	Mutation rewiring degron network	0.0833
p.H50R	DO26769	LUSC	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation altering degron motif	0.8244
p.L946F	DO222753	MELA	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.1111
p.E35K	DO50659	ORCA	ICGC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation rewiring degron network	0.1389
p.G1437W	DO28009	OV	ICGC	ATSSS	DEG_SPOP_SBC_1	1434:1438	Mutation altering degron motif	0.7825
p.A1458S	DO32912	PACA	ICGC	ASSTS	DEG_SPOP_SBC_1	1446:1450	Mutation rewiring degron network	0.1111
p.S736P	DO228138	PBCA	ICGC	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation blocking phosphorylation signal	0.6667
p.P1652T	DO232761	PBCA	ICGC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation altering degron motif	0.7031
p.R1664H	DO51407	PRAD	ICGC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.1111
p.G38S	DO219331	PRAD	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.0833
p.G38S	DO219331	PRAD	ICGC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation rewiring degron network	0.2222
p.F944L	DO36881	READ	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.1667
p.F944L	DO43306	UCEC	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.1667
p.P943S	DO47282	SKCM	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.1944
p.P943S	DO37778	SKCM	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.1944
p.G719E	DO37432	SKCM	ICGC	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation rewiring degron network	0.0833
p.D1448V	DO37444	SKCM	ICGC	ASSTS	DEG_SPOP_SBC_1	1446:1450	Mutation altering degron motif	0.7785
p.R1205L	DO50279	SKCM	ICGC	PPSY	ITCH	1213:1216	Mutation rewiring degron network	0.1111
p.S930I	DO37931	SKCM	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.2222
p.V39A	DO51269	SKCM	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.1111
p.V39A	DO51269	SKCM	ICGC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation rewiring degron network	0.25
p.P41Q	DO38171	SKCM	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.1667
p.P41Q	DO38171	SKCM	ICGC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation rewiring degron network	0.3056
p.P41L	DO47767	STAD	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.1667
p.P41L	DO47767	STAD	ICGC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation rewiring degron network	0.3056
p.G57D	DO38328	STAD	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.3056
p.G57D	DO38328	STAD	ICGC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation rewiring degron network	0.0833
p.K1446Q	DO219773	UCEC	ICGC	ASSTS	DEG_SPOP_SBC_1	1446:1450	Mutation altering degron motif	0.6944
p.V1648M	DO50078	UCEC	ICGC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.2222
p.V1648M	DO50078	UCEC	ICGC	LQPYFE	LIG_APCC_ABBA_1	1637:1642	Mutation rewiring degron network	0.1667
p.T939I	DO40996	UCEC	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.3056
p.V36L	DO42033	UCEC	ICGC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation rewiring degron network	0.1667
p.P1382S	DO41752	UCEC	ICGC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.1111
p.P37L	DO41871	UCEC	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation substituting flanking lysine	0.1667
p.P37L	DO41871	UCEC	ICGC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation substituting flanking lysine	0.3056
p.V1440G	DO41235	UCEC	ICGC	ATSSS	DEG_SPOP_SBC_1	1434:1438	Mutation blocking phosphorylation signal	0.7222
p.V1440G	DO41235	UCEC	ICGC	ASSTS	DEG_SPOP_SBC_1	1446:1450	Mutation blocking phosphorylation signal	0.6111
p.R1407W	DO43755	UCEC	ICGC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.0833
p.R1664C	DO41199	UCEC	ICGC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.1111
p.T926N	DO42472	UCEC	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.1111
p.A945D	DO42472	UCEC	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.1389
p.L1455I	DO41488	UCEC	ICGC	ASSTS	DEG_SPOP_SBC_1	1446:1450	Mutation rewiring degron network	0.1944
p.L1455I	ACH-000996	Endometrial/Uterine Cancer	CCLE	ASSTS	DEG_SPOP_SBC_1	1446:1450	Mutation rewiring degron network	0.1944
p.S925N	DO42673	UCEC	ICGC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.0833
p.A727V	DO42673	UCEC	ICGC	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation rewiring degron network	0.3056
p.Q60H	DO42665	UCEC	ICGC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.2222
p.G1644V	SIDM01156	Small Cell Lung Carcinoma	GDSC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.1111
p.G1644V	SIDM01156	Small Cell Lung Carcinoma	GDSC	LQPYFE	LIG_APCC_ABBA_1	1637:1642	Mutation rewiring degron network	0.2778
p.G1644V	SW1271	lung	COSMIC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.1111
p.G1644V	SW1271	lung	COSMIC	LQPYFE	LIG_APCC_ABBA_1	1637:1642	Mutation rewiring degron network	0.2778
p.R1206H	SIDM00513	Non-Small Cell Lung Carcinoma	GDSC	PPSY	ITCH	1213:1216	Mutation rewiring degron network	0.1389
p.R1206H	SIDM00198	Ewing's Sarcoma	GDSC	PPSY	ITCH	1213:1216	Mutation rewiring degron network	0.1389
p.R1206H	SIDM00230	Small Cell Lung Carcinoma	GDSC	PPSY	ITCH	1213:1216	Mutation rewiring degron network	0.1389
p.E1400K	SIDM00731	Small Cell Lung Carcinoma	GDSC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.2778
p.E1400K	NCI-H2196	lung	COSMIC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.2778
p.S1215P	SIDM00529	Breast Carcinoma	GDSC	PPSY	ITCH	1213:1216	Mutation altering degron motif	0.6752
p.S1215P	SIDM00793	Burkitt's Lymphoma	GDSC	PPSY	ITCH	1213:1216	Mutation altering degron motif	0.6752
p.S1215P	SIDM01173	Rhabdomyosarcoma	GDSC	PPSY	ITCH	1213:1216	Mutation altering degron motif	0.6752
p.Q932P	SIDM01100	Neuroblastoma	GDSC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.2778
p.Q932P	SIDM00459	B-Cell Non-Hodgkin's Lymphoma	GDSC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation rewiring degron network	0.2778
p.L56P	SIDM01045	Endometrial Carcinoma	GDSC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation altering degron motif	0.6471
p.L56P	ACH-000978	Endometrial/Uterine Cancer	CCLE	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation altering degron motif	0.6471
p.L56P	EN	endometrium	COSMIC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation altering degron motif	0.6471
p.A1219V	SIDM00898	Breast Carcinoma	GDSC	PPSY	ITCH	1213:1216	Mutation rewiring degron network	0.25
p.A1219V	ACH-000248	Breast Cancer	CCLE	PPSY	ITCH	1213:1216	Mutation rewiring degron network	0.25
p.H57R	SIDM01015	Chronic Myelogenous Leukemia	GDSC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.3056
p.H57R	SIDM01015	Chronic Myelogenous Leukemia	GDSC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation rewiring degron network	0.0833
p.E49K	SIDM01102	Non-Cancerous	GDSC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation altering degron motif	0.591
p.E49K	ACH-002316	Non-Cancerous	CCLE	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation altering degron motif	0.591
p.E49K	WIL2-NS	haematopoietic and lymphoid tissue	COSMIC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation altering degron motif	0.591
p.A1666V	SIDM00438	B-Lymphoblastic Leukemia	GDSC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.0556
p.A1666V	MN-60	haematopoietic and lymphoid tissue	COSMIC	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.0556
p.G1389S	SIDM00404	B-Cell Non-Hodgkin's Lymphoma	GDSC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.3056
p.G1389S	SU-DHL-16	haematopoietic and lymphoid tissue	COSMIC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.3056
p.H1396Y	SIDM01617	Endometrial Carcinoma	GDSC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation altering degron motif	0.6118
p.T721I	ACH-000027	Brain Cancer	CCLE	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation substituting flanking lysine	0.25
p.D1425N	ACH-000648	Lung Cancer	CCLE	ATSSS	DEG_SPOP_SBC_1	1434:1438	Mutation rewiring degron network	0.0833
p.D1425N	NCI-H28	pleura	COSMIC	ATSSS	DEG_SPOP_SBC_1	1434:1438	Mutation rewiring degron network	0.0833
p.Y57C	ACH-000786	Lymphoma	CCLE	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.3056
p.Y57C	ACH-000786	Lymphoma	CCLE	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation rewiring degron network	0.0833
p.Y57C	Daudi	haematopoietic and lymphoid tissue	COSMIC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.3056
p.Y57C	Daudi	haematopoietic and lymphoid tissue	COSMIC	KSSVHSE	LIG_APCC_ABBAyCdc20_2	42:48	Mutation rewiring degron network	0.0833
p.R1444C	ACH-000999	Colon/Colorectal Cancer	CCLE	ATSSS	DEG_SPOP_SBC_1	1434:1438	Mutation rewiring degron network	0.1667
p.R1444C	ACH-000999	Colon/Colorectal Cancer	CCLE	ASSTS	DEG_SPOP_SBC_1	1446:1450	Mutation rewiring degron network	0.2778
p.R1444C	SNU-1040	large intestine	COSMIC	ATSSS	DEG_SPOP_SBC_1	1434:1438	Mutation rewiring degron network	0.1667
p.R1444C	SNU-1040	large intestine	COSMIC	ASSTS	DEG_SPOP_SBC_1	1446:1450	Mutation rewiring degron network	0.2778
p.A63T	ACH-000999	Colon/Colorectal Cancer	CCLE	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.1389
p.A63T	SNU-1040	large intestine	COSMIC	SEEDDFVPEL	DEG_COP1_1	47:56	Mutation rewiring degron network	0.1389
p.R1650S	ACH-001061	Colon/Colorectal Cancer	CCLE	PYSSS	DEG_SPOP_SBC_1	1652:1656	Mutation rewiring degron network	0.2778
p.R1650S	ACH-001061	Colon/Colorectal Cancer	CCLE	LQPYFE	LIG_APCC_ABBA_1	1637:1642	Mutation rewiring degron network	0.1111
p.A1383P	ACH-001451	Cervical Cancer	CCLE	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.1389
p.P1382L	SUP-M2	haematopoietic and lymphoid tissue	COSMIC	ARVPLLHLR	DEG_APCC_DBOX_1	1390:1398	Mutation rewiring degron network	0.1111
p.D941N	NCI-H2342	lung	COSMIC	ASSST	DEG_SPOP_SBC_1	934:938	Mutation substituting flanking lysine	0.3611
p.C737F	NCI-H82	lung	COSMIC	PRSSS	DEG_SPOP_SBC_1	728:732	Mutation rewiring degron network	0.1944

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ARHGAP32

UniProt ID: A7KAX9

Entrez ID: 9743

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ARHGAP32 in