DegronMD - O75553(DAB1)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L279V	TCGA-05-4420	LUAD	TCGA	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation altering degron motif	0.5654
p.Q360K	TCGA-25-2404	OV	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.6944
p.Q360K	TCGA-78-7536	LUAD	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.6944
p.D507Y	TCGA-29-1770	OV	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation altering degron motif	0.7325
p.D507Y	TCGA-29-1770	OV	TCGA	PVTST	DEG_SPOP_SBC_1	504:508	Mutation altering degron motif	0.7325
p.P273Q	TCGA-38-4629	LUAD	TCGA	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.1667
p.S493F	TCGA-3N-A9WC	SKCM	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1389
p.S493F	TCGA-DA-A1I1	SKCM	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1389
p.S493F	SIDM00134	Non-Small Cell Lung Carcinoma	GDSC	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1389
p.S493F	ACH-000825	Lung Cancer	CCLE	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1389
p.S493F	HOP-92	lung	COSMIC	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1389
p.P423S	TCGA-3N-A9WD	SKCM	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.3056
p.P492A	TCGA-55-7907	LUAD	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1111
p.P355S	TCGA-60-2710	LUSC	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1944
p.P355S	TCGA-D3-A2J8	SKCM	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1944
p.P368T	TCGA-78-7535	LUAD	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.7031
p.Q419K	TCGA-91-6829	LUAD	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.6944
p.R429H	TCGA-A6-6781	COAD	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1389
p.R429H	TCGA-CM-6171	COAD	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1389
p.E511D	TCGA-AA-3663	COAD	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.2222
p.E511D	TCGA-AA-3663	COAD	TCGA	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.25
p.P424L	TCGA-AA-3695	COAD	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.2778
p.P424L	TCGA-F7-A624	HNSC	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.2778
p.P424L	SIDM00217	Colorectal Carcinoma	GDSC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.2778
p.P424L	ACH-000999	Colon/Colorectal Cancer	CCLE	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.2778
p.P424L	SNU-1040	large intestine	COSMIC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.2778
p.E514Q	TCGA-AG-4008	READ	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1389
p.E514Q	TCGA-AG-4008	READ	TCGA	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.1667
p.V289I	TCGA-AJ-A3EK	UCEC	TCGA	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.1944
p.T369I	TCGA-AP-A1DK	UCEC	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.3056
p.S498F	TCGA-AP-A1DV	UCEC	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.2778
p.S498F	TCGA-AP-A1DV	UCEC	TCGA	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.1667
p.S498F	SK-MEL-2	skin	COSMIC	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.2778
p.S498F	SK-MEL-2	skin	COSMIC	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.1667
p.A283T	TCGA-AU-6004	COAD	TCGA	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation altering degron motif	0.7139
p.L375S	TCGA-B5-A1MW	UCEC	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1389
p.P503S	TCGA-BF-AAP2	SKCM	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation altering degron motif	0.6752
p.V372A	TCGA-BG-A222	UCEC	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.2222
p.T414M	TCGA-BR-A4QL	STAD	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.2778
p.Q419H	TCGA-CF-A1HS	BLCA	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.7582
p.D417N	TCGA-D3-A8GI	SKCM	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.6932
p.D417N	TCGA-DA-A3F8	SKCM	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.6932
p.D417N	TCGA-EE-A2GI	SKCM	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.6932
p.Q351H	TCGA-DA-A3F3	SKCM	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0833
p.D502N	TCGA-DA-A95Z	SKCM	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation altering degron motif	0.6932
p.A500T	TCGA-DF-A2KU	UCEC	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation altering degron motif	0.7139
p.Q277K	TCGA-DS-A1OC	CESC	TCGA	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.2778
p.S287R	TCGA-EB-A430	SKCM	TCGA	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.25
p.M410I	TCGA-EB-A6QY	SKCM	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1667
p.M410I	TCGA-EE-A29D	SKCM	TCGA	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1667
p.M410I	SIDM00591	Oral Cavity Carcinoma	GDSC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1667
p.M410I	ACH-002045	Head and Neck Cancer	CCLE	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1667
p.M410I	HO-1-u-1	upper aerodigestive tract	COSMIC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1667
p.F291V	TCGA-EE-A3J5	SKCM	TCGA	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.1389
p.P362L	TCGA-FR-A3YO	SKCM	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.7582
p.D507N	TCGA-FS-A1ZZ	SKCM	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation altering degron motif	0.6932
p.D507N	TCGA-FS-A1ZZ	SKCM	TCGA	PVTST	DEG_SPOP_SBC_1	504:508	Mutation altering degron motif	0.6932
p.S495L	TCGA-GF-A6C9	SKCM	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1944
p.S495L	TCGA-GF-A6C9	SKCM	TCGA	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.0833
p.P355A	TCGA-MN-A4N5	LUAD	TCGA	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1944
p.E514G	TCGA-SI-A71O	SARC	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1389
p.E514G	TCGA-SI-A71O	SARC	TCGA	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.1667
p.P516L	TCGA-W3-AA1V	SKCM	TCGA	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.0833
p.P516L	TCGA-W3-AA1V	SKCM	TCGA	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.1111
p.D375Y	DO486	BLCA	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1389
p.C352S	DO486	BLCA	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1111
p.D371N	DO219594	BRCA	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.25
p.E425D	DO9346	COAD	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.25
p.A279T	DO230343	COCA	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation altering degron motif	0.7139
p.S429R	DO50348	ESAD	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1389
p.V271L	DO234410	ESAD	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.1111
p.E355K	DO44438	HNSC	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1944
p.F376Y	DO48701	LIRI	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1111
p.I378N	DO48701	LIRI	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0556
p.S431N	DO229177	LMS	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.0833
p.Q274K	DO26414	LUAD	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation substituting flanking lysine	0.3056
p.Q274K	DO32049	OV	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation substituting flanking lysine	0.3056
p.P406A	DO25396	LUAD	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.0556
p.P269A	DO45332	LUAD	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.0556
p.Q368H	DO23624	LUAD	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.7582
p.P282T	DO24860	LUAD	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation altering degron motif	0.7031
p.P269S	DO26938	LUSC	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.0556
p.P269S	DO37778	SKCM	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.0556
p.FE427LK	DO222702	MELA	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0
p.D421Y	DO31664	OV	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.7325
p.S429N	DO51510	PACA	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1389
p.L350F	DO48574	PAEN	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0556
p.E428Q	DO36386	READ	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1667
p.V366L	DO46844	RECA	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.6765
p.E428G	DO220273	SARC	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1667
p.D369N	DO218900	SKCA	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.3056
p.P430S	DO218849	SKCA	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1111
p.P276L	DO37419	SKCM	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.25
p.D421N	DO37412	SKCM	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.6932
p.S407F	DO37966	SKCM	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.0833
p.S407F	DO51234	SKCM	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.0833
p.D377Y	DO38075	SKCM	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0833
p.P430L	DO51276	SKCM	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1111
p.S358F	DO51254	SKCM	ICGC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.2778
p.S409L	DO51254	SKCM	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1389
p.D416N	DO219481	SKCM	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.6932
p.P417S	DO219466	SKCM	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.6752
p.T283I	DO42033	UCEC	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation altering degron motif	0.7078
p.A414T	DO223286	UCEC	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.2778
p.S412F	DO43186	UCEC	ICGC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.2222
p.V286A	DO42977	UCEC	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.2778
p.L289S	DO42913	UCEC	ICGC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.1944
p.S515C	SIDM02070	Esophageal Carcinoma	GDSC	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1111
p.S515C	SIDM02070	Esophageal Carcinoma	GDSC	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.1389
p.Q352H	SIDM01036	Plasma Cell Myeloma	GDSC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1111
p.Q352H	ACH-000653	Myeloma	CCLE	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1111
p.Q352H	JJN-3	haematopoietic and lymphoid tissue	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1111
p.P376A	SIDM00845	Burkitt's Lymphoma	GDSC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1111
p.P376A	ACH-000786	Lymphoma	CCLE	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1111
p.S515R	SIDM00193	Colorectal Carcinoma	GDSC	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1111
p.S515R	SIDM00193	Colorectal Carcinoma	GDSC	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.1389
p.S515R	ACH-000991	Colon/Colorectal Cancer	CCLE	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1111
p.S515R	ACH-000991	Colon/Colorectal Cancer	CCLE	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.1389
p.S515R	SNU-81	large intestine	COSMIC	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1111
p.S515R	SNU-81	large intestine	COSMIC	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.1389
p.R429C	SIDM01154	T-Lymphoblastic Leukemia	GDSC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1389
p.R429C	ACH-000953	Leukemia	CCLE	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1389
p.R429C	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1389
p.A378T	SIDM00936	Bladder Carcinoma	GDSC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0556
p.A378T	ACH-000142	Bladder Cancer	CCLE	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0556
p.A378T	CAL-29	urinary tract	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0556
p.P362Q	SIDM00740	Squamous Cell Lung Carcinoma	GDSC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.7035
p.P362Q	ACH-000747	Lung Cancer	CCLE	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.7035
p.P362Q	NCI-H1703	lung	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.7035
p.A378V	SIDM00145	T-Lymphoblastic Leukemia	GDSC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0556
p.A378V	ACH-001127	Leukemia	CCLE	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0556
p.A378V	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0556
p.P368A	SIDM01435	Hepatocellular Carcinoma	GDSC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.7503
p.P368A	ACH-000686	Liver Cancer	CCLE	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.7503
p.A294D	ACH-000012	Lung Cancer	CCLE	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.0556
p.A294D	ACH-000029	Lung Cancer	CCLE	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.0556
p.A294D	ACH-000993	Endometrial/Uterine Cancer	CCLE	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.0556
p.P518T	ACH-000303	Gastric Cancer	CCLE	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.0556
p.P518T	NCI-SNU-5	stomach	COSMIC	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.0556
p.A411S	ACH-000795	Leukemia	CCLE	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1944
p.P289L	GP5d	large intestine	COSMIC	LELFGD	LIG_APCC_ABBA_1	279:284	Mutation rewiring degron network	0.1944
p.A376V	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1111
p.A376T	CAL-29	urinary tract	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.1111
p.Q350H	JJN-3	haematopoietic and lymphoid tissue	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.0556
p.I372V	CRO-AP2	haematopoietic and lymphoid tissue	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.2222
p.A363T	REH	haematopoietic and lymphoid tissue	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.7139
p.Q370R	MOLP-8	haematopoietic and lymphoid tissue	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation rewiring degron network	0.2778
p.S491F	HOP-92	lung	COSMIC	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.0833
p.A411T	CAL-29	urinary tract	COSMIC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1944
p.T426M	RS4-11	haematopoietic and lymphoid tissue	COSMIC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.2222
p.A411V	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1944
p.S513R	SNU-81	large intestine	COSMIC	LNLTPVTS	DEG_SCF_FBW7_1	500:507	Mutation rewiring degron network	0.1667
p.S513R	SNU-81	large intestine	COSMIC	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.1944
p.P422L	SNU-1040	large intestine	COSMIC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.7582
p.R427C	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1944
p.T422A	IST-MES1	pleura	COSMIC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation altering degron motif	0.7139
p.P360Q	NCI-H1703	lung	COSMIC	PPVAQVMPG	DEG_SIAH_1	360:368	Mutation altering degron motif	0.5924
p.M408I	HO-1-u-1	upper aerodigestive tract	COSMIC	PLTPLAT	DEG_SCF_FBW7_1	416:422	Mutation rewiring degron network	0.1111
p.E518K	SW684	soft tissue	COSMIC	PVTST	DEG_SPOP_SBC_1	504:508	Mutation rewiring degron network	0.0556

DegronMD: protein-targeted degradation, mutation and drug response to degrons

DAB1

UniProt ID: O75553

Entrez ID: 1600

Protein name: Disabled homolog 1

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for DAB1 in