p.K395N | TCGA-17-Z033 | LUAD | TCGA | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1944 |
p.P449L | TCGA-2F-A9KT | BLCA | TCGA | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1389 |
p.R333Q | TCGA-44-A47B | LUAD | TCGA | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.1667 |
p.A347P | TCGA-55-8299 | LUAD | TCGA | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation blocking phosphorylation signal | 0.75 |
p.A347P | DO25927 | LUAD | ICGC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation blocking phosphorylation signal | 0.75 |
p.S355F | TCGA-78-7155 | LUAD | TCGA | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation substituting flanking lysine | 0.1944 |
p.S355F | DO23590 | LUAD | ICGC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation substituting flanking lysine | 0.1944 |
p.R392H | TCGA-AA-A022 | COAD | TCGA | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1111 |
p.R392H | DO10647 | COAD | ICGC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1111 |
p.K413T | TCGA-AG-A002 | READ | TCGA | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1944 |
p.A450V | TCGA-AP-A0LP | UCEC | TCGA | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1667 |
p.A450V | DO43146 | UCEC | ICGC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1667 |
p.Q412H | TCGA-AX-A2IO | UCEC | TCGA | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.2222 |
p.Q412H | DO40800 | UCEC | ICGC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.2222 |
p.G672E | TCGA-BF-A3DM | SKCM | TCGA | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.7199 |
p.G672E | DO48667 | SKCM | ICGC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.7199 |
p.A464T | TCGA-BG-A222 | UCEC | TCGA | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.2222 |
p.A464T | DO42977 | UCEC | ICGC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.2222 |
p.R348C | TCGA-D1-A17Q | UCEC | TCGA | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.2778 |
p.R348C | TCGA-EO-A22R | UCEC | TCGA | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.2778 |
p.R348C | DO41903 | UCEC | ICGC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.2778 |
p.R348C | DO42713 | UCEC | ICGC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.2778 |
p.E410K | TCGA-D3-A8GI | SKCM | TCGA | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.2778 |
p.E410K | TCGA-W3-AA1V | SKCM | TCGA | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.2778 |
p.E410K | DO50284 | SKCM | ICGC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.2778 |
p.E410K | DO51276 | SKCM | ICGC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.2778 |
p.P671S | TCGA-D5-6928 | COAD | TCGA | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.6752 |
p.P671S | DO7776 | COAD | ICGC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.6752 |
p.E403Q | TCGA-D8-A1J8 | BRCA | TCGA | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation altering degron motif | 0.6744 |
p.E403Q | DO1269 | BRCA | ICGC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation altering degron motif | 0.6744 |
p.K399N | TCGA-D9-A6EC | SKCM | TCGA | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.3056 |
p.R334M | TCGA-DF-A2KN | UCEC | TCGA | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation substituting flanking lysine | 0.3056 |
p.R334M | DO223282 | UCEC | ICGC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation substituting flanking lysine | 0.3056 |
p.R334M | KCL-22 | haematopoietic and lymphoid tissue | COSMIC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation substituting flanking lysine | 0.3056 |
p.R333L | TCGA-E6-A1LX | UCEC | TCGA | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.1667 |
p.R333L | NCI-H345 | lung | COSMIC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.1667 |
p.R234K | TCGA-EE-A29G | SKCM | TCGA | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.7237 |
p.E397K | TCGA-ER-A193 | SKCM | TCGA | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation blocking phosphorylation signal | 0.6944 |
p.E397K | DO47368 | SKCM | ICGC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation blocking phosphorylation signal | 0.6944 |
p.S231Y | TCGA-F5-6814 | READ | TCGA | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.712 |
p.S231Y | DO36556 | READ | ICGC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.712 |
p.S231Y | SIDM01611 | Endometrial Carcinoma | GDSC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.712 |
p.R220P | TCGA-L9-A8F4 | LUAD | TCGA | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation rewiring degron network | 0.0833 |
p.R220P | DO49876 | LUAD | ICGC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation rewiring degron network | 0.0833 |
p.A447T | TCGA-W3-A828 | SKCM | TCGA | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.0833 |
p.A447T | DO51273 | SKCM | ICGC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.0833 |
p.T231M | DO222427 | BTCA | ICGC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.8534 |
p.S457L | DO222990 | BTCA | ICGC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7667 |
p.S457L | DO229028 | LICA | ICGC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7667 |
p.K409N | DO233258 | GACA | ICGC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.3056 |
p.R239T | DO219026 | HNSC | ICGC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation rewiring degron network | 0.2222 |
p.P220T | DO228986 | LICA | ICGC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation rewiring degron network | 0.0833 |
p.A343E | DO229015 | LICA | ICGC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.7701 |
p.R392C | DO222363 | MELA | ICGC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1111 |
p.P338S | DO222653 | MELA | ICGC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.3056 |
p.S339F | DO219871 | SKCA | ICGC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.7982 |
p.S339F | DO229453 | SKCA | ICGC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.7982 |
p.L221F | DO218863 | SKCA | ICGC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation rewiring degron network | 0.1111 |
p.G674R | DO218861 | SKCA | ICGC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.7568 |
p.A663T | DO38404 | STAD | ICGC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation rewiring degron network | 0.1389 |
p.A663T | DO229253 | THCA | ICGC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation rewiring degron network | 0.1389 |
p.P343L | DO42312 | UCEC | ICGC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.7582 |
p.A351T | SIDM01289 | Esophageal Carcinoma | GDSC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01034 | B-Lymphoblastic Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01020 | Plasma Cell Myeloma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01265 | Plasma Cell Myeloma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00425 | Ovarian Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00615 | Hepatocellular Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00611 | Kidney Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00614 | Hepatocellular Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00144 | Non-Small Cell Lung Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01197 | Colorectal Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00565 | Oral Cavity Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00411 | Pancreatic Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00393 | Gastric Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00781 | Colorectal Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01069 | Non-Small Cell Lung Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00553 | Acute Myeloid Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01005 | Acute Myeloid Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00465 | Ovarian Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00374 | B-Cell Non-Hodgkin's Lymphoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00492 | Glioblastoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01032 | Esophageal Squamous Cell Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00092 | Ovarian Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00351 | Oral Cavity Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01079 | Melanoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00562 | Breast Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00278 | Esophageal Squamous Cell Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01045 | Endometrial Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00489 | Oral Cavity Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00290 | Gastric Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00609 | Kidney Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00347 | Esophageal Squamous Cell Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00368 | Small Cell Lung Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00306 | Non-Small Cell Lung Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00361 | Non-Small Cell Lung Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00316 | Glioblastoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00412 | B-Cell Non-Hodgkin's Lymphoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01608 | Endometrial Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01569 | Hepatocellular Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01617 | Endometrial Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01470 | Acute Myeloid Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01460 | Glioma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01336 | Glioblastoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00166 | Other Solid Cancers | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01573 | Plasma Cell Myeloma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00780 | Colorectal Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM00784 | Glioma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01658 | Unknown | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01685 | B-Lymphoblastic Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01753 | Gastric Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.S465L | SIDM01574 | Plasma Cell Myeloma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.1944 |
p.M459T | SIDM01034 | B-Lymphoblastic Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00425 | Ovarian Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01020 | Plasma Cell Myeloma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01265 | Plasma Cell Myeloma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00615 | Hepatocellular Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00611 | Kidney Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00614 | Hepatocellular Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01197 | Colorectal Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00565 | Oral Cavity Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00411 | Pancreatic Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00393 | Gastric Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00781 | Colorectal Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01069 | Non-Small Cell Lung Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00553 | Acute Myeloid Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01005 | Acute Myeloid Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00465 | Ovarian Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00374 | B-Cell Non-Hodgkin's Lymphoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00492 | Glioblastoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01032 | Esophageal Squamous Cell Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00092 | Ovarian Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00351 | Oral Cavity Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01079 | Melanoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00562 | Breast Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00278 | Esophageal Squamous Cell Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01045 | Endometrial Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00489 | Oral Cavity Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00290 | Gastric Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00609 | Kidney Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00347 | Esophageal Squamous Cell Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00368 | Small Cell Lung Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00306 | Non-Small Cell Lung Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00361 | Non-Small Cell Lung Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00316 | Glioblastoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00412 | B-Cell Non-Hodgkin's Lymphoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00785 | Acute Myeloid Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01608 | Endometrial Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01569 | Hepatocellular Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01617 | Endometrial Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01470 | Acute Myeloid Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01460 | Glioma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01444 | Glioblastoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01336 | Glioblastoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00166 | Other Solid Cancers | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01573 | Plasma Cell Myeloma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00780 | Colorectal Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM00784 | Glioma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01658 | Unknown | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01685 | B-Lymphoblastic Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01753 | Gastric Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.M459T | SIDM01574 | Plasma Cell Myeloma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7423 |
p.R342M | SIDM01004 | Chronic Myelogenous Leukemia | GDSC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.8632 |
p.R342M | KCL-22 | haematopoietic and lymphoid tissue | COSMIC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.8632 |
p.A464G | SIDM00723 | Non-Small Cell Lung Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.2222 |
p.G661E | SIDM00632 | Non-Cancerous | GDSC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation rewiring degron network | 0.0833 |
p.G661E | IM-9 | haematopoietic and lymphoid tissue | COSMIC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation rewiring degron network | 0.0833 |
p.P679L | SIDM00633 | Breast Carcinoma | GDSC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation rewiring degron network | 0.2778 |
p.P679L | SIDM00052 | Esophageal Squamous Cell Carcinoma | GDSC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation rewiring degron network | 0.2778 |
p.P679L | SIDM00758 | Non-Small Cell Lung Carcinoma | GDSC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation rewiring degron network | 0.2778 |
p.P679L | SIDM00757 | Non-Small Cell Lung Carcinoma | GDSC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation rewiring degron network | 0.2778 |
p.T676R | SIDM00633 | Breast Carcinoma | GDSC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.7876 |
p.T676R | SIDM00052 | Esophageal Squamous Cell Carcinoma | GDSC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.7876 |
p.T676R | SIDM00758 | Non-Small Cell Lung Carcinoma | GDSC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.7876 |
p.T676R | SIDM00863 | Burkitt's Lymphoma | GDSC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.7876 |
p.T676R | SIDM00757 | Non-Small Cell Lung Carcinoma | GDSC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.7876 |
p.A343V | SIDM01259 | B-Lymphoblastic Leukemia | GDSC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.6936 |
p.A343V | GR-ST | haematopoietic and lymphoid tissue | COSMIC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.6936 |
p.R356C | SIDM00277 | Acute Myeloid Leukemia | GDSC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.0556 |
p.R356C | SIDM01159 | Other Sarcomas | GDSC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.0556 |
p.R356C | SIDM00783 | Colorectal Carcinoma | GDSC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.0556 |
p.R341L | SIDM00719 | Small Cell Lung Carcinoma | GDSC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.8428 |
p.R341L | NCI-H345 | lung | COSMIC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.8428 |
p.M459L | SIDM00629 | Breast Carcinoma | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.711 |
p.T446I | SIDM00951 | T-Lymphoblastic Leukemia | GDSC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.0556 |
p.T446I | CTV-1 | haematopoietic and lymphoid tissue | COSMIC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.0556 |
p.Q390P | SIDM00850 | Gastric Carcinoma | GDSC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.0556 |
p.Q390P | AGS | stomach | COSMIC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.0556 |
p.G341D | ACH-000272 | Kidney Cancer | CCLE | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.6087 |
p.A418T | ACH-000328 | Brain Cancer | CCLE | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.0556 |
p.L230M | ACH-000351 | Gastric Cancer | CCLE | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.5999 |
p.L230M | MKN1 | stomach | COSMIC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.5999 |
p.D675E | ACH-000985 | Colon/Colorectal Cancer | CCLE | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.5647 |
p.D675E | LS-411N | large intestine | COSMIC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation altering degron motif | 0.5647 |
p.R415W | ACH-000988 | Endometrial/Uterine Cancer | CCLE | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1389 |
p.R415W | MFE-319 | endometrium | COSMIC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1389 |
p.H234Y | ACH-001452 | Leukemia | CCLE | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.6118 |
p.H234Y | BONNA-12 | haematopoietic and lymphoid tissue | COSMIC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.6118 |
p.T416I | ACH-001737 | Leukemia | CCLE | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1111 |
p.T416I | ACH-002222 | Leukemia | CCLE | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1111 |
p.T416I | CTV-1 | haematopoietic and lymphoid tissue | COSMIC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1111 |
p.R400W | MFE-319 | endometrium | COSMIC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation altering degron motif | 0.8634 |
p.K454N | HCC2998 | large intestine | COSMIC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.2778 |
p.S231L | SUP-T1 | haematopoietic and lymphoid tissue | COSMIC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.7667 |
p.S231L | HCC2998 | large intestine | COSMIC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.7667 |
p.R234L | JHH-7 | liver | COSMIC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.8428 |
p.D329Y | RS4-11 | haematopoietic and lymphoid tissue | COSMIC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation rewiring degron network | 0.0556 |
p.K462E | CW-2 | large intestine | COSMIC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.2778 |
p.E346K | PANC-08-13 | pancreas | COSMIC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.7022 |
p.E398K | PANC-08-13 | pancreas | COSMIC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.2778 |
p.E678Q | PE/CA-PJ15 | upper aerodigestive tract | COSMIC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation rewiring degron network | 0.3056 |
p.T401I | CTV-1 | haematopoietic and lymphoid tissue | COSMIC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation altering degron motif | 0.7078 |
p.E455K | PANC-08-13 | pancreas | COSMIC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.3056 |
p.D660E | LS-411N | large intestine | COSMIC | VESTPDLE | DEG_SCF_FBW7_2 | 670:677 | Mutation rewiring degron network | 0.0556 |
p.A335V | GR-ST | haematopoietic and lymphoid tissue | COSMIC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation blocking phosphorylation signal | 0.6667 |
p.R463G | SCC90 | upper aerodigestive tract | COSMIC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.25 |
p.H219Y | BONNA-12 | haematopoietic and lymphoid tissue | COSMIC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation blocking phosphorylation signal | 0.5 |
p.L413P | TE-4 | oesophagus | COSMIC | GRAPLVKVE | DEG_APCC_DBOX_1 | 400:408 | Mutation rewiring degron network | 0.1944 |
p.Q345P | AGS | stomach | COSMIC | LPGTPRPT | DEG_SCF_FBW7_1 | 339:346 | Mutation altering degron motif | 0.7035 |
p.D460Y | RS4-11 | haematopoietic and lymphoid tissue | COSMIC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation altering degron motif | 0.7325 |
p.P235Q | COR-L321 | NS | COSMIC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation altering degron motif | 0.7035 |
p.L470P | TE-4 | oesophagus | COSMIC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.0556 |
p.A469D | SW626 | ovary | COSMIC | APSST | DEG_SPOP_SBC_1 | 456:460 | Mutation rewiring degron network | 0.0833 |
p.A219V | GR-ST | haematopoietic and lymphoid tissue | COSMIC | LLTPTHS | DEG_SCF_FBW7_1 | 229:235 | Mutation blocking phosphorylation signal | 0.5 |