DegronMD - Q9HCM2(PLXNA4)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.I1028M	TCGA-05-4398	LUAD	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6507
p.I1028M	TCGA-CX-7086	HNSC	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6507
p.I1028M	DO15046	HNSC	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6507
p.I1028M	DO25847	LUAD	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6507
p.S1619I	TCGA-17-Z055	LUAD	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.2222
p.S1619I	TCGA-A5-A0G2	UCEC	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.2222
p.S1619I	DO41235	UCEC	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.2222
p.D1031V	TCGA-29-1781	OV	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.7785
p.D1031V	DO29578	OV	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.7785
p.Y1627F	TCGA-37-4135	LUSC	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.8639
p.Y1627F	DO26806	LUSC	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.8639
p.L119V	TCGA-44-5644	LUAD	TCGA	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.25
p.L119V	TCGA-44-5644	LUAD	TCGA	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.L119V	DO25153	LUAD	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.25
p.L119V	DO25153	LUAD	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.R99S	TCGA-66-2769	LUSC	TCGA	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.R99S	DO26522	LUSC	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.G1648V	TCGA-73-4677	LUAD	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2778
p.G1648V	DO23768	LUAD	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2778
p.R99L	TCGA-86-8358	LUAD	TCGA	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.R99L	DO25471	LUAD	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.D1632N	TCGA-A1-A0SF	BRCA	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.1389
p.D1632N	TCGA-A1-A0SF	BRCA	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.3056
p.D1632N	DO1342	BRCA	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.1389
p.D1632N	DO1342	BRCA	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.3056
p.R1635H	TCGA-AA-3680	COAD	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2222
p.R1635H	TCGA-AA-3680	COAD	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.2222
p.R1635H	TCGA-AX-A05Z	UCEC	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2222
p.R1635H	TCGA-AX-A05Z	UCEC	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.2222
p.R1635H	TCGA-CD-A4MG	STAD	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2222
p.R1635H	TCGA-CD-A4MG	STAD	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.2222
p.R1635H	DO9980	COAD	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2222
p.R1635H	DO9980	COAD	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.2222
p.R1635H	DO48009	STAD	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2222
p.R1635H	DO48009	STAD	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.2222
p.R1635H	DO40884	UCEC	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2222
p.R1635H	DO40884	UCEC	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.2222
p.A1026V	TCGA-AD-6964	COAD	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.5825
p.A1026V	DO8360	COAD	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.5825
p.A1026V	DO229177	LMS	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.5825
p.K123N	TCGA-AX-A06F	UCEC	TCGA	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation altering degron motif	0.6918
p.K123N	DO41752	UCEC	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation altering degron motif	0.6918
p.V101I	TCGA-AX-A06F	UCEC	TCGA	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1667
p.V101I	DO229016	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1667
p.V101I	DO41752	UCEC	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1667
p.R1615S	TCGA-AX-A2HC	UCEC	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.1111
p.R1615S	TCGA-K4-A54R	BLCA	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.1111
p.R1615S	DO48611	BLCA	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.1111
p.R1615S	DO41572	UCEC	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.1111
p.D1039A	TCGA-AZ-4315	COAD	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1111
p.D1039A	DO8842	COAD	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1111
p.S1633I	TCGA-B5-A0JY	UCEC	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation blocking phosphorylation signal	0.6111
p.S1633I	TCGA-B5-A0JY	UCEC	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation blocking phosphorylation signal	0.7222
p.S1633I	DO43041	UCEC	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation blocking phosphorylation signal	0.6111
p.S1633I	DO43041	UCEC	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation blocking phosphorylation signal	0.7222
p.N112S	TCGA-B5-A0JY	UCEC	TCGA	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.0556
p.N112S	TCGA-B5-A0JY	UCEC	TCGA	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.3056
p.N112S	DO43041	UCEC	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.0556
p.N112S	DO43041	UCEC	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.3056
p.D1031Y	TCGA-B5-A1MR	UCEC	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.7325
p.D1031Y	DO41758	UCEC	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.7325
p.G1648A	TCGA-CG-4462	STAD	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2778
p.G1648A	DO38292	STAD	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2778
p.L1645V	TCGA-CR-7398	HNSC	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation altering degron motif	0.5654
p.L1645V	DO14782	HNSC	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation altering degron motif	0.5654
p.E124D	TCGA-D1-A16X	UCEC	TCGA	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation altering degron motif	0.6758
p.E124D	DO41799	UCEC	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation altering degron motif	0.6758
p.N1623S	TCGA-D1-A17Q	UCEC	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.7069
p.N1623S	DO41903	UCEC	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.7069
p.R1025K	TCGA-D3-A8GM	SKCM	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6126
p.R1025K	DO50288	SKCM	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6126
p.E1016G	TCGA-D9-A6EC	SKCM	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.0833
p.E1016G	DO50291	SKCM	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.0833
p.Y134H	TCGA-DI-A1BU	UCEC	TCGA	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.1111
p.Y134H	DO42023	UCEC	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.1111
p.N115D	TCGA-DI-A1BU	UCEC	TCGA	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.1389
p.N115D	TCGA-DI-A1BU	UCEC	TCGA	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.2222
p.N115D	DO42023	UCEC	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.1389
p.N115D	DO42023	UCEC	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.2222
p.R1025S	TCGA-DK-A6AV	BLCA	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.7427
p.R1025S	DO48575	BLCA	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.7427
p.S1633N	TCGA-EE-A20H	SKCM	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation blocking phosphorylation signal	0.6111
p.S1633N	TCGA-EE-A20H	SKCM	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation blocking phosphorylation signal	0.7222
p.S1633N	DO37986	SKCM	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation blocking phosphorylation signal	0.6111
p.S1633N	DO37986	SKCM	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation blocking phosphorylation signal	0.7222
p.L119I	TCGA-EE-A2MJ	SKCM	TCGA	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.25
p.L119I	TCGA-EE-A2MJ	SKCM	TCGA	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.L119I	DO38099	SKCM	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.25
p.L119I	DO38099	SKCM	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.L1634F	TCGA-EE-A2MR	SKCM	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.1944
p.L1634F	TCGA-EE-A2MR	SKCM	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.25
p.L1634F	DO37819	SKCM	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.1944
p.L1634F	DO37819	SKCM	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.25
p.Y122C	TCGA-EJ-5509	PRAD	TCGA	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation altering degron motif	0.5976
p.Y122C	DO36255	PRAD	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation altering degron motif	0.5976
p.D1039N	TCGA-FS-A1ZZ	SKCM	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1111
p.D1039N	DO37412	SKCM	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1111
p.R1637Q	TCGA-FW-A3R5	SKCM	TCGA	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2778
p.R1637Q	TCGA-FW-A3R5	SKCM	TCGA	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.1667
p.R1637Q	DO37406	SKCM	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2778
p.R1637Q	DO37406	SKCM	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.1667
p.K116N	TCGA-IB-7651	PAAD	TCGA	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation substituting flanking lysine	0.2778
p.K116N	TCGA-IB-7651	PAAD	TCGA	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation substituting flanking lysine	0.3056
p.K116N	DO46657	PAAD	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation substituting flanking lysine	0.2778
p.K116N	DO46657	PAAD	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation substituting flanking lysine	0.3056
p.V1037M	TCGA-JY-A6FB	ESCA	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1667
p.K1027M	TCGA-VQ-A91S	STAD	TCGA	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6951
p.K1027M	DO222352	STAD	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6951
p.P97S	TCGA-YG-AA3N	SKCM	TCGA	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.0556
p.P97S	DO51298	SKCM	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.0556
p.P1643H	DO230323	COCA	ICGC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation altering degron motif	0.7694
p.T111N	DO227872	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation altering degron motif	0.7055
p.T111N	DO52491	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation altering degron motif	0.7055
p.V114I	DO233764	GACA	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.1111
p.V114I	DO233764	GACA	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.25
p.R99H	DO228816	LICA	ICGC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.R99H	SIDM00951	T-Lymphoblastic Leukemia	GDSC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.R99H	ACH-002222	Leukemia	CCLE	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.R99H	CTV-1	haematopoietic and lymphoid tissue	COSMIC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1111
p.M1624V	DO231031	LUSC	ICGC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.6097
p.G136S	DO233294	NACA	ICGC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.0556
p.S1020P	DO229227	THCA	ICGC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1944
p.M1017I	SIDM00791	Chronic Myelogenous Leukemia	GDSC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1111
p.M1017I	ACH-000068	Lymphoma	CCLE	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1111
p.M1017I	ACH-000551	Leukemia	CCLE	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1111
p.M1017I	ACH-002061	Leukemia	CCLE	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1111
p.M1017I	K-562	haematopoietic and lymphoid tissue	COSMIC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1111
p.S1630I	SIDM00848	Ewing's Sarcoma	GDSC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.7341
p.S1630I	ACH-000052	Bone Cancer	CCLE	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.7341
p.S1630I	A673	bone	COSMIC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.7341
p.S1020L	SIDM00633	Breast Carcinoma	GDSC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1944
p.S1020L	ACH-000759	Breast Cancer	CCLE	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1944
p.S1020L	MDA-MB-175-VII	breast	COSMIC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.1944
p.E124G	SIDM00660	Colorectal Carcinoma	GDSC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation altering degron motif	0.7199
p.E124G	ACH-000985	Colon/Colorectal Cancer	CCLE	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation altering degron motif	0.7199
p.E124G	LS-411N	large intestine	COSMIC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation altering degron motif	0.7199
p.Q1022R	SIDM00465	Ovarian Carcinoma	GDSC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.25
p.Q1022R	ACH-002183	Ovarian Cancer	CCLE	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.25
p.Q1022R	OVMIU	ovary	COSMIC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation rewiring degron network	0.25
p.P1631S	SIDM00320	Non-Small Cell Lung Carcinoma	GDSC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.6752
p.P1631S	ACH-001233	Lung Cancer	CCLE	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.6752
p.P1631S	VMRC-LCD	lung	COSMIC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation altering degron motif	0.6752
p.N113S	SIDM01154	T-Lymphoblastic Leukemia	GDSC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.0833
p.N113S	SIDM01154	T-Lymphoblastic Leukemia	GDSC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.2778
p.N113S	ACH-000953	Leukemia	CCLE	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.0833
p.N113S	ACH-000953	Leukemia	CCLE	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.2778
p.N113S	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	YKENR	DEG_APCC_KENBOX_2	122:126	Mutation rewiring degron network	0.0833
p.N113S	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.2778
p.R1615M	SIDM00934	Pancreatic Carcinoma	GDSC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.1111
p.R1615M	ACH-000354	Pancreatic Cancer	CCLE	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.1111
p.R1615M	CAPAN-1	pancreas	COSMIC	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.1111
p.H1653Q	SIDM00925	Non-Small Cell Lung Carcinoma	GDSC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.1389
p.H1653Q	ACH-000638	Lung Cancer	CCLE	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.1389
p.H1653Q	NCI-H441	lung	COSMIC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.1389
p.H1029Y	SIDM00140	Melanoma	GDSC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6118
p.H1029Y	ACH-000968	Skin Cancer	CCLE	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6118
p.H1029Y	COLO-792	skin	COSMIC	RAKIHQD	LIG_APCC_ABBAyCdc20_2	1025:1031	Mutation altering degron motif	0.6118
p.V1655A	SIDM00519	Mesothelioma	GDSC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.0833
p.V1655A	ACH-002135	Lung Cancer	CCLE	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.0833
p.V1655A	H2869	pleura	COSMIC	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.0833
p.Q102K	SIDM01612	Endometrial Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1944
p.Q102K	ACH-000946	Endometrial/Uterine Cancer	CCLE	PLTTT	DEG_SPOP_SBC_1	107:111	Mutation rewiring degron network	0.1944
p.R1637W	ACH-001518	Endometrial/Uterine Cancer	CCLE	PMITPDLE	DEG_SCF_FBW7_2	1639:1646	Mutation rewiring degron network	0.2778
p.R1637W	ACH-001518	Endometrial/Uterine Cancer	CCLE	NMIRYTGSP	CBL_PTK	1623:1631	Mutation rewiring degron network	0.1667

DegronMD: protein-targeted degradation, mutation and drug response to degrons

PLXNA4

UniProt ID: Q9HCM2

Entrez ID: 91584

Protein name: Plexin-A4

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for PLXNA4 in