DegronMD - Q9NSC2(SALL1)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G312V	TCGA-17-Z062	LUAD	TCGA	PQSSS	DEG_SPOP_SBC_1	322:326	Mutation rewiring degron network	0.0556
p.P598H	TCGA-35-5375	LUAD	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.6583
p.P598H	TCGA-ER-A19B	SKCM	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.6583
p.P598H	DO25290	LUAD	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.6583
p.P598H	DO47491	SKCM	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.6583
p.P598H	SIDM00845	Burkitt's Lymphoma	GDSC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.6583
p.P598H	Daudi	haematopoietic and lymphoid tissue	COSMIC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.6583
p.P1109Q	TCGA-46-3767	LUSC	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7035
p.P1109Q	DO26650	LUSC	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7035
p.V356L	TCGA-50-5930	LUAD	TCGA	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.2778
p.V356L	DO25189	LUAD	ICGC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.2778
p.S442F	TCGA-55-6972	LUAD	TCGA	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation altering degron motif	0.7982
p.S442F	DO25010	LUAD	ICGC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation altering degron motif	0.7982
p.S373T	TCGA-55-8089	LUAD	TCGA	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.6005
p.S373T	DO23690	LUAD	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.6005
p.P431L	TCGA-55-8204	LUAD	TCGA	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.1389
p.P431L	DO45322	LUAD	ICGC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.1389
p.P431T	TCGA-55-8204	LUAD	TCGA	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.1389
p.P431T	DO45322	LUAD	ICGC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.1389
p.S151I	TCGA-55-8511	LUAD	TCGA	APSSS	DEG_SPOP_SBC_1	148:152	Mutation altering degron motif	0.7341
p.S151I	DO24940	LUAD	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation altering degron motif	0.7341
p.A171V	TCGA-56-8308	LUSC	TCGA	AITTS	DEG_SPOP_SBC_1	171:175	Mutation altering degron motif	0.5825
p.A171V	TCGA-A5-A0G2	UCEC	TCGA	AITTS	DEG_SPOP_SBC_1	171:175	Mutation altering degron motif	0.5825
p.A171V	TCGA-CD-A4MG	STAD	TCGA	AITTS	DEG_SPOP_SBC_1	171:175	Mutation altering degron motif	0.5825
p.A171V	TCGA-FI-A2D0	UCEC	TCGA	AITTS	DEG_SPOP_SBC_1	171:175	Mutation altering degron motif	0.5825
p.A171V	DO219140	LUSC	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation altering degron motif	0.5825
p.A171V	DO48009	STAD	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation altering degron motif	0.5825
p.A171V	DO41235	UCEC	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation altering degron motif	0.5825
p.A171V	DO43891	UCEC	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation altering degron motif	0.5825
p.S166F	TCGA-86-8278	LUAD	TCGA	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.1944
p.S166F	DO26308	LUAD	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.1944
p.S1096F	TCGA-90-A4ED	LUSC	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.1667
p.S1096F	DO45482	LUSC	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.1667
p.S143R	TCGA-95-7562	LUAD	TCGA	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1944
p.S143R	DO51196	LUAD	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1944
p.G162D	TCGA-99-7458	LUAD	TCGA	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.0556
p.G162D	TCGA-99-7458	LUAD	TCGA	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.0833
p.G162D	DO25416	LUAD	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.0556
p.G162D	DO25416	LUAD	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.0833
p.V365A	TCGA-A5-A0G2	UCEC	TCGA	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation rewiring degron network	0.2222
p.V365A	DO41235	UCEC	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation rewiring degron network	0.2222
p.T147I	TCGA-A5-A2K5	UCEC	TCGA	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.3056
p.T147I	DO41379	UCEC	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.3056
p.A346V	TCGA-AA-3967	COAD	TCGA	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.2778
p.A346V	DO10124	COAD	ICGC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.2778
p.A346V	SIDM01953	Colorectal Carcinoma	GDSC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.2778
p.S1106R	TCGA-AJ-A2QO	UCEC	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.6316
p.S1106R	DO42177	UCEC	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.6316
p.P351L	TCGA-AJ-A3EK	UCEC	TCGA	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.7582
p.P351L	DO41584	UCEC	ICGC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.7582
p.P351L	SIDM00449	B-Lymphoblastic Leukemia	GDSC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.7582
p.P351L	ACH-000922	Leukemia	CCLE	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.7582
p.P351L	RCH-ACV	haematopoietic and lymphoid tissue	COSMIC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.7582
p.P322S	TCGA-AP-A059	UCEC	TCGA	PQSSS	DEG_SPOP_SBC_1	322:326	Mutation altering degron motif	0.6752
p.P322S	DO41361	UCEC	ICGC	PQSSS	DEG_SPOP_SBC_1	322:326	Mutation altering degron motif	0.6752
p.G160D	TCGA-AP-A1E0	UCEC	TCGA	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1111
p.G160D	DO43154	UCEC	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1111
p.V1093M	TCGA-AX-A1CE	UCEC	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.0833
p.V1093M	DO234308	ESAD	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.0833
p.V1093M	DO42280	UCEC	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.0833
p.V365I	TCGA-BA-A6D8	HNSC	TCGA	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation rewiring degron network	0.2222
p.V365I	DO44426	HNSC	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation rewiring degron network	0.2222
p.G1111W	TCGA-BF-A1PX	SKCM	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7825
p.G1111W	DO51236	SKCM	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7825
p.A379S	TCGA-BR-A4IZ	STAD	TCGA	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation rewiring degron network	0.1667
p.A379S	DO38647	STAD	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation rewiring degron network	0.1667
p.F1092C	TCGA-CA-6717	COAD	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.0556
p.F1092C	DO8264	COAD	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.0556
p.N604S	TCGA-CG-5721	STAD	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.2222
p.N604S	DO38192	STAD	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.2222
p.A438V	TCGA-D1-A103	UCEC	TCGA	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation altering degron motif	0.5825
p.A438V	DO232761	PBCA	ICGC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation altering degron motif	0.5825
p.A438V	DO42312	UCEC	ICGC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation altering degron motif	0.5825
p.G312C	TCGA-D3-A2JP	SKCM	TCGA	PQSSS	DEG_SPOP_SBC_1	322:326	Mutation rewiring degron network	0.0556
p.G312C	DO47407	SKCM	ICGC	PQSSS	DEG_SPOP_SBC_1	322:326	Mutation rewiring degron network	0.0556
p.P1120S	TCGA-D3-A3CB	SKCM	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.1111
p.P1120S	TCGA-D3-A3CB	SKCM	TCGA	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation rewiring degron network	0.2222
p.P1120S	DO47386	SKCM	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.1111
p.P1120S	DO47386	SKCM	ICGC	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation rewiring degron network	0.2222
p.R603K	TCGA-D3-A8GI	SKCM	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.25
p.R603K	TCGA-DA-A1IC	SKCM	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.25
p.R603K	DO220872	MELA	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.25
p.R603K	DO37430	SKCM	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.25
p.R603K	DO50284	SKCM	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.25
p.S590L	TCGA-D3-A8GL	SKCM	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation blocking phosphorylation signal	0.6667
p.S590L	DO50287	SKCM	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation blocking phosphorylation signal	0.6667
p.S373L	TCGA-D3-A8GQ	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	TCGA-DA-A95Y	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	TCGA-EE-A2GI	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	TCGA-GN-A266	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	DO222427	BTCA	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	DO220851	MELA	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	DO37410	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	DO37432	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	DO223908	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	DO51246	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	SIDM00140	Melanoma	GDSC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	ACH-000968	Skin Cancer	CCLE	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S373L	COLO-792	skin	COSMIC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7667
p.S590P	TCGA-D7-6818	STAD	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation blocking phosphorylation signal	0.6667
p.S590P	DO38262	STAD	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation blocking phosphorylation signal	0.6667
p.G596W	TCGA-D9-A148	SKCM	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.7825
p.G596W	DO37971	SKCM	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.7825
p.S335C	TCGA-DD-AACT	LIHC	TCGA	PQSSS	DEG_SPOP_SBC_1	322:326	Mutation rewiring degron network	0.0833
p.S335C	DO219563	LIHC	ICGC	PQSSS	DEG_SPOP_SBC_1	322:326	Mutation rewiring degron network	0.0833
p.V1108D	TCGA-DD-AAEI	LIHC	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7785
p.V1108D	DO219575	LIHC	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7785
p.S151R	TCGA-DM-A0XD	COAD	TCGA	APSSS	DEG_SPOP_SBC_1	148:152	Mutation altering degron motif	0.7427
p.S151R	DO10228	COAD	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation altering degron motif	0.7427
p.P351Q	TCGA-DX-A7EF	SARC	TCGA	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.7035
p.P351Q	DO220021	SARC	ICGC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.7035
p.P351S	TCGA-EB-A41B	SKCM	TCGA	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.6752
p.P351S	DO37611	SKCM	ICGC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.6752
p.P587L	TCGA-EB-A431	SKCM	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.1389
p.P587L	DO37671	SKCM	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.1389
p.P1097S	TCGA-EE-A29B	SKCM	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.1944
p.P1097S	DO47255	SKCM	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.1944
p.P609S	TCGA-EE-A29E	SKCM	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.0833
p.P609S	DO37831	SKCM	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.0833
p.G589S	TCGA-EE-A3JD	SKCM	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.1944
p.G589S	DO50299	SKCM	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.1944
p.I343T	TCGA-EJ-7315	PRAD	TCGA	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.1944
p.I343T	DO36259	PRAD	ICGC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.1944
p.E599K	TCGA-FJ-A3Z7	BLCA	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.591
p.E599K	DO463	BLCA	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.591
p.T139I	TCGA-FS-A4F0	SKCM	TCGA	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.0833
p.T139I	DO37891	SKCM	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.0833
p.L1122P	TCGA-HC-7752	PRAD	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.0556
p.L1122P	TCGA-HC-7752	PRAD	TCGA	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation rewiring degron network	0.1667
p.L1122P	DO36267	PRAD	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.0556
p.L1122P	DO36267	PRAD	ICGC	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation rewiring degron network	0.1667
p.G589D	TCGA-IN-A6RN	STAD	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.1944
p.G589D	DO51739	STAD	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.1944
p.V348I	TCGA-IQ-A6SH	HNSC	TCGA	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.5965
p.V348I	DO223268	HNSC	ICGC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.5965
p.M341I	TCGA-KK-A6E6	PRAD	TCGA	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.1389
p.M341I	DO51361	PRAD	ICGC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.1389
p.V433A	TCGA-LC-A66R	BLCA	TCGA	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.1944
p.V433A	DO44031	BLCA	ICGC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.1944
p.A369T	TCGA-MN-A4N1	LUAD	TCGA	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7139
p.A369T	DO45328	LUAD	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.7139
p.R603G	TCGA-NC-A5HN	LUSC	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.25
p.R603G	DO52025	LUSC	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.25
p.P587H	TCGA-VQ-A8P2	STAD	TCGA	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.1389
p.P587H	DO51761	STAD	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.1389
p.D1099N	TCGA-WE-A8K5	SKCM	TCGA	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.25
p.D1099N	DO51282	SKCM	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.25
p.Q178E	TCGA-ZJ-AAXU	CESC	TCGA	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.25
p.Q178E	DO219759	CESC	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.25
p.E444G	DO1199	BRCA	ICGC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.2778
p.G161S	DO222736	BTCA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.0833
p.G161S	DO222736	BTCA	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.0556
p.G161S	SIDM00397	Acute Myeloid Leukemia	GDSC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.0833
p.G161S	SIDM00397	Acute Myeloid Leukemia	GDSC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.0556
p.G161S	SIDM00549	B-Lymphoblastic Leukemia	GDSC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.0833
p.G161S	SIDM00549	B-Lymphoblastic Leukemia	GDSC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.0556
p.G160S	DO222817	BTCA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1111
p.G160S	DO233778	GACA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1111
p.G160S	DO228993	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1111
p.G160S	DO221002	WT	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1111
p.G1104D	DO7776	COAD	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7198
p.S159G	DO227987	COCA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO228581	GACA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO228909	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO228908	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO228931	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO228947	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO228991	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO229025	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO229040	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO229059	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO231110	LUSC	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.S159G	DO229248	THCA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1389
p.A377G	DO222503	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation rewiring degron network	0.2222
p.P1109L	DO234185	ESAD	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7582
p.G138S	DO223140	ESCA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.0556
p.T173A	DO233154	GACA	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation altering degron motif	0.7139
p.K450M	DO233885	GACA	ICGC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation substituting flanking lysine	0.2222
p.G163S	DO233861	GACA	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.1111
p.G163S	DO229542	UTCA	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.1111
p.G163S	SIDM01617	Endometrial Carcinoma	GDSC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.1111
p.G163S	ACH-000994	Endometrial/Uterine Cancer	CCLE	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.1111
p.F1120V	DO48495	KIRP	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.1111
p.F1120V	DO48495	KIRP	ICGC	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation rewiring degron network	0.2222
p.D140Y	DO22650	LGG	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1111
p.S158G	DO228947	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation rewiring degron network	0.1667
p.A584S	DO50914	LICA	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.0556
p.I331V	DO231848	LINC	ICGC	PQSSS	DEG_SPOP_SBC_1	322:326	Mutation rewiring degron network	0.1944
p.A1094E	DO23907	LUAD	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.1111
p.V1108I	DO230940	LUSC	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7076
p.V1108I	DO224584	LUSC	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7076
p.T602K	DO230971	LUSC	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.2778
p.T602K	DO224630	LUSC	ICGC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.2778
p.T1105I	DO222662	MELA	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7078
p.P1120A	DO222702	MELA	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.1111
p.P1120A	DO222702	MELA	ICGC	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation rewiring degron network	0.2222
p.N342T	DO232224	PBCA	ICGC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.1667
p.R1098W	DO51151	PRAD	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.2222
p.R1098W	DO229502	SKCA	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.2222
p.R1098W	DO43306	UCEC	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.2222
p.T1092P	DO229456	SKCA	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.0556
p.D1123N	DO50287	SKCM	ICGC	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation rewiring degron network	0.1389
p.S166P	DO229213	THCA	ICGC	AITTS	DEG_SPOP_SBC_1	171:175	Mutation rewiring degron network	0.1944
p.L1109I	DO40884	UCEC	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.7174
p.R1099Q	DO43755	UCEC	ICGC	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation rewiring degron network	0.25
p.N367S	SIDM00683	Prostate Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation rewiring degron network	0.2778
p.S372T	SIDM00491	Thyroid Gland Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.6005
p.S372T	ACH-001443	Thyroid Cancer	CCLE	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.6005
p.S372T	ASH-3	thyroid	COSMIC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.6005
p.V348A	SIDM00447	B-Lymphoblastic Leukemia	GDSC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.6936
p.V348A	ACH-000960	Leukemia	CCLE	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.6936
p.V348A	REH	haematopoietic and lymphoid tissue	COSMIC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation altering degron motif	0.6936
p.S593G	SIDM01242	Melanoma	GDSC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation blocking phosphorylation signal	0.75
p.S593G	ACH-002162	Skin Cancer	CCLE	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation blocking phosphorylation signal	0.75
p.S593G	MMAC-SF	skin	COSMIC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation blocking phosphorylation signal	0.75
p.P317S	SIDM01986	Non-Small Cell Lung Carcinoma	GDSC	PQSSS	DEG_SPOP_SBC_1	322:326	Mutation rewiring degron network	0.1944
p.S428G	SIDM01146	Gastric Carcinoma	GDSC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.0556
p.S428G	ACH-000932	Gastric Cancer	CCLE	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.0556
p.S428G	NCI-SNU-1	stomach	COSMIC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.0556
p.S1116F	SIDM00688	B-Cell Non-Hodgkin's Lymphoma	GDSC	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation altering degron motif	0.7982
p.S1116F	ACH-002253	Lymphoma	CCLE	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation altering degron motif	0.7982
p.S1116F	JSC-1	haematopoietic and lymphoid tissue	COSMIC	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation altering degron motif	0.7982
p.T434A	SIDM01612	Endometrial Carcinoma	GDSC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.2222
p.T434A	ACH-000946	Endometrial/Uterine Cancer	CCLE	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation rewiring degron network	0.2222
p.A369V	SIDM01694	B-Lymphoblastic Leukemia	GDSC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation altering degron motif	0.5825
p.A148T	SIDM01729	Endometrial Carcinoma	GDSC	APSSS	DEG_SPOP_SBC_1	148:152	Mutation altering degron motif	0.7139
p.P588S	SIDM00159	Biliary Tract Carcinoma	GDSC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.1667
p.A346G	ACH-000784	Esophageal Cancer	CCLE	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.2778
p.A584T	ACH-000911	Gastric Cancer	CCLE	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.0556
p.T1103P	ACH-001704	Skin Cancer	CCLE	DTPTSHVPSGP	DEG_COP1_1	1102:1112	Mutation altering degron motif	0.5919
p.E590D	BICR10	upper aerodigestive tract	COSMIC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation blocking phosphorylation signal	0.6667
p.A1126V	NCI-H630	large intestine	COSMIC	PLSSS	DEG_SPOP_SBC_1	1112:1116	Mutation rewiring degron network	0.0556
p.N600H	RL95-2	endometrium	COSMIC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.7423
p.C357R	HCT-15	large intestine	COSMIC	VTTPSSE	DEG_SCF_FBW7_2	348:354	Mutation rewiring degron network	0.25
p.P379S	CML-T1	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation rewiring degron network	0.1667
p.L597M	SNU-175	large intestine	COSMIC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation altering degron motif	0.711
p.A586V	VM-CUB-1	urinary tract	COSMIC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation blocking phosphorylation signal	0.5556
p.T442I	HEC-1	endometrium	COSMIC	AKSTS	DEG_SPOP_SBC_1	438:442	Mutation altering degron motif	0.7078
p.E590K	SNU-175	large intestine	COSMIC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation blocking phosphorylation signal	0.6667
p.K381M	NCI-H1993	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	369:373	Mutation rewiring degron network	0.1111
p.S331G	NCI-SNU-1	stomach	COSMIC	PQSSS	DEG_SPOP_SBC_1	322:326	Mutation rewiring degron network	0.1944
p.D602N	H513	pleura	COSMIC	DSGGPES	DEG_SCF_TRCP1_1	594:600	Mutation rewiring degron network	0.2778

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SALL1

UniProt ID: Q9NSC2

Entrez ID: 6299

Protein name: Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SALL1 in