| Tag | Content |
|---|---|
| Uniprot ID | A0A0G2JWF7 |
| Entrez ID | 289736 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_006251198.3 |
| Ensembl protein ID | ENSRNOP00000069862 |
| Ensembl nucleotide ID | ENSRNOG00000019624 |
| Gene name | MORC family CW-type zinc finger 2 |
| Gene symbol | Morc2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAFTNYSSLN RAQLTFEYLH TNSTTHEFLF GALAELVDNA RDADATRIDI YAERREDLRG 60 GFMLCFLDDG AGMDPSDAAS VIQFGKSAKR TPESTQIGQY GNGLKSGSMR IGKDFILFTK 120 KEDTMTCLFL SRTFHEEEGI DEVIVPLPTW NARTREPITD NVEKFAIETE LVYKYSPFHT 180 EEQVMNQFMK IPGNSGTLVI IFNLKLMDNG EPELDIISNP KDIQMAETSP EGTKPERRSF 240 RAYAAVLYID PRMRIFIHGH KVQTKRLSCC LYKPRMYKYT SSRFKTRAEQ EVKKAEHVAR 300 IAEEKAREAE SKARTLEVRM GGDLTRDSRV MLRQVQNAAI TLRREADVKK RIKDAKQRAL 360 KEPKELNFVF GVNIEHRDLD GMFIYNCSRL IKMYEKVGPQ LEGGMACGGV VGVVDVPYLV 420 LEPTHNKQDF ADAKEYRHLL RAMGEHLAQY WKDIAIAQRG IIKFWDEFGY LSANWNQPPS 480 SELRFKRRRA MEIPTTIQCD LCLKWRTLPF QLSSVEKDYP DTWVCSMNPD PEQDRCEASE 540 QKQKVPLGTL KKDPKSQEEK QKQLTEKIRQ QQEKLEALQK TTPIRSQADL KKLPLEVTTR 600 PSTEEPVRRP QRPRSPPLPA VIKNAPSRPP SIQTPRPATQ LRKTSVISSP KPPATAARGE 660 TSTSRILQPA EAPRKPANLP IKTVPRPTPT VQTPSPSLIP NSKNLREVPA QKAIKTPMVK 720 KPEPPAKQSM ASSGRKRSLV VSDEEEAEEE AEKRKERCKR GKLAVKEEKK EANELSDSAG 780 EDDPAELKKA QKDKGLHVEV RVNREWYTGR VTAVEMGKNV VRWKVKFDYV PTDTTPRDRW 840 VEKGSEDVRL MKPPSPEHQS PDTQQEGGEE EEAMVAQQAV ALPEPSTSDG LPIEPDTTAT 900 STSHETIDLL VQILRNCLRY FLPPSFPISK KELSVMNSEE LISFPLKEYF KQYEVGLQNL 960 CHSYQSRADS RAKASEESLR TSEKKLRETE EKLQKLRTNI VALLQKVQED IDINTDDELD 1020 AYIEDLITKG D 1031 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MORC2 | 486358 | E2RBF9 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | MORC2 | A0A452FN52 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MORC2 | 22880 | Q9Y6X9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Morc2a | 74522 | Q69ZX6 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MORC2 | 458763 | K7D393 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MORC2 | F1RPD9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Morc2 | 289736 | A0A0G2JWF7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | morc2 | 445488 | Q68EG7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0000792 | heterochromatin |
| GO:0016363 | nuclear matrix |
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0016887 | ATPase activity |
| GO:0003682 | chromatin binding |
| GO:0042393 | histone binding |
| GO:0000287 | magnesium ion binding |
| GO:0042803 | protein homodimerization activity |
| GO:0008270 | zinc ion binding |
| GO:0006974 | cellular response to DNA damage stimulus |
| GO:0006338 | chromatin remodeling |
| GO:0045814 | negative regulation of gene expression, epigenetic |
| GO:0045869 | negative regulation of single stranded viral RNA replication via double stranded DNA intermediate |
| GO:0090309 | positive regulation of methylation-dependent chromatin silencing |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51050 | ZF_CW |