Gene: morc2

Basic information

Tag Content
Uniprot ID Q68EG7
Entrez ID 445488
Genbank protein ID AAH80267.1
Genbank nucleotide ID XM_009297717.2; NM_001003994.1; XM_005174236.3;
Ensembl protein ID ENSDARP00000030104
Ensembl nucleotide ID ENSDARG00000028539
Gene name MORC family CW-type zinc finger 2
Gene symbol morc2
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAYTNYSSLN RAQLTFEYLH TNSTTHEFLF GALAELVDNS RDANATRIDI YTEKRPDLRG 60
GFMLCFLDDG TGMEPSEATH VIQFGKSSKR FPESTHIGQY GNGLKSGSMR IGKDFILFTK 120
KDEKLTCLFL SRTFHEEEGL DEVIVPLPSW DAKTQQPLTQ DTEKYATETE LIFKYSPFKN 180
EEQLFRQFNK IEGPSGTLVV VYNLKLMDNR EPELDIETDH QDIMMAGTPV EGVKPERRSF 240
RAYAAVLYID PRMRIFIQGH KVRTKRLSCC LYNPRMYKYT STRFKTRAEQ EVKKADHLAK 300
LAEEKAREAE SKARMLEIKV GDDLSKEARA SLRKAQDSAV ALRAEATRKQ AIHASKQKAL 360
KEPKELNFIF GVNIQRRDQD GMFVYNCSRL IKMYEKTGPQ LEGGMACGGV VGVVDVPYLV 420
LEPTHNKQDF ADAKEYRHLL RAMGDYLAQY WKDIGIAQKG IVKFWDEFGY LSANWNSNPS 480
NEIQFRRRRA MEIPVTIQCD KCLKWRTLPF QMDAVDKRYP DSWVCLMNPD GSQDRCDAAE 540
QKQNLPVGIL KKDLKSSEDK QKDLTEKIRQ QQEKLEAMQK TTTIKSAADI KRLPLEVSAK 600
TTEERSPQPT RSSQRAAPRP RSPPLPAVVR RAVSQQQIVK TPPPKPAPPS RPTRTPPAPP 660
PKAKSSPAPA KKPAPKHVAP PPPPPTKTPA RRSAAQSRTP TPSSAKSAAK QTPTNKKAII 720
KKGRVQEEDE EEEESEEEEE EEEEEEEEED SGSEEDEPQP KKSKMAAPVQ ARGKTVVEKK 780
PAAAAVVKQT NTEVIANSTN EDLKKDAAKN AQKDKGILVE AKVNGEWFTG RVTAVETGKD 840
NVRWKVKFDY VPMNTPRDRW VFKGSDDVRL MRPASPESRS PDTNQGPARS VTPPTAAEPD 900
TTQSGPSRET SEGLVTMMRT LLRYFFPPDF RIPKDSVNTM SAEDLVAFPI KEYFQQYEAG 960
LQSLCNSYQT RAESRARAVE EKSSGAETKL RESEEKLRKL RTNIVALLQK VQEDIEISSD 1020
DELDAYIEDL VTKGE 1035

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMORC2486358E2RBF9Canis lupus familiarisPredictionMore>>
1:1 orthologMORC2A0A452FN52Capra hircusPredictionMore>>
1:1 orthologMORC222880Q9Y6X9Homo sapiensPredictionMore>>
1:1 orthologMorc2a74522Q69ZX6CPOMus musculusPublicationMore>>
1:1 orthologMORC2458763K7D393Pan troglodytesPredictionMore>>
1:1 orthologMORC2F1RPD9Sus scrofaPredictionMore>>
1:1 orthologMorc2289736A0A0G2JWF7Rattus norvegicusPredictionMore>>
1:1 orthologmorc2445488Q68EG7Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0008270 zinc ion binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0539 Nucleus
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR036890 HATPase_C_sf
IPR041006 Morc_S5
IPR011124 Znf_CW

PROSITE

PROSITE ID PROSITE Term
PS51050 ZF_CW

Pfam

Pfam ID Pfam Term
PF17942 Morc6_S5
PF07496 zf-CW