Gene: MORC2

Basic information

Tag Content
Uniprot ID E2RBF9
Entrez ID 486358
Genbank protein ID
Genbank nucleotide ID XM_543484.6
Ensembl protein ID ENSCAFP00000018956
Ensembl nucleotide ID ENSCAFG00000012861
Gene name MORC family CW-type zinc finger 2
Gene symbol MORC2
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAFTNYSSLN RAQLTFEYLH TNSTTHEFLF GALAELVDNA RDADATRIDI YAERREDLRG 60
GFMLCFLDDG AGMDPSDAAS VIQFGKSAKR TPESTQIGQY GNGLKSGSMR IGKDFILFTK 120
KEDTMTCLFL SRTFHEEEGI DEVIVPLPTW NARTREPVTD NVEKFAIETE LIYKYSPFRN 180
EEEVMTQFMK IPGDSGTLVI IFNLKLMDNG EPELDIISNP RDIQMAETSP EGTKPERRSF 240
RAYAAVLYID PRMRIFIHGH KVQTKRLSCC LYKPRMYKYT SSRFKTRAEQ EVKKAEHVAR 300
IAEEKAREAE SKARTLEVRL GGDLTRDSRV MLRQVQNTAI TLRREADVKK RIKEAKQRAL 360
KEPKELNFVF GVNIEHRDLD GMFIYNCSRL IKMYEKVGPQ LEGGMACGGV VGVVDVPYLV 420
LEPTHNKQDF ADAKEYRHLL RAMGEHLAQY WKDIAIAQRG IIKFWDEFGY LSANWNQPPS 480
SELRYKRRRA MEIPTTIQCD LCLKWRTLPF QLSSVEKDYP DTWVCSMNPD PEQDRCEASE 540
QKQKVPLGTF RKDLKTQEEK QKQLTEKIRQ QQEKLEALQK TTPIRSQADL KKLPLEVTTR 600
PSTEEPARRP QRPRSPPLPA VIKNAPSRPP SLQAPRPASQ PRKAPVISST PKPSTLAARE 660
EASTSRLLQP PEAPRKPANT PAKTAPRPTP MVQPLSPSLL PNAKSPREVP APRAIKTPVV 720
KKPEPPSKLS PTTPGRKRTL GVSDEEEAEE EAERRKERSK RGKFAVKEEK KDLNELSDSA 780
GEEDPADLKR AQKDKGLHVE VRVNREWYTG RVTAVEVGKH VVRWKVKFDY VPTDTTPRDR 840
WVEKGSEDVR LMKPPSPEYQ SPDTQQEGGE EEEEEAAVAA PPAPPAAAAQ QAVATAEPST 900
SDCIRIEPDT TAPSTNHETI DLLVQILRNC LRYFLPPSFP ISKKELSAMN SDELISFPLK 960
EYFKQYEVGL QNLCHSYQSR ADSRAKASEE SLRTSERKLR ETEEKLQKLR TNIVALLQKV 1020
QEDIDINTDD ELDAYIEDLI TKGD 1044

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMORC2486358E2RBF9Canis lupus familiarisPredictionMore>>
1:1 orthologMORC2A0A452FN52Capra hircusPredictionMore>>
1:1 orthologMORC222880Q9Y6X9Homo sapiensPredictionMore>>
1:1 orthologMorc2a74522Q69ZX6CPOMus musculusPublicationMore>>
1:1 orthologMORC2458763K7D393Pan troglodytesPredictionMore>>
1:1 orthologMORC2F1RPD9Sus scrofaPredictionMore>>
1:1 orthologMorc2289736A0A0G2JWF7Rattus norvegicusPredictionMore>>
1:1 orthologmorc2445488Q68EG7Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0008270 zinc ion binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR036890 HATPase_C_sf
IPR041006 Morc_S5
IPR011124 Znf_CW

PROSITE

PROSITE ID PROSITE Term
PS51050 ZF_CW

Pfam

Pfam ID Pfam Term
PF17942 Morc6_S5
PF07496 zf-CW