Gene: Tanc2

Basic information

Tag Content
Uniprot ID A0A0G2K9J0
Entrez ID 303599
Genbank protein ID
Genbank nucleotide ID XM_008768352.2; XM_008768351.2;
Ensembl protein ID ENSRNOP00000075014
Ensembl nucleotide ID ENSRNOG00000052840
Gene name Protein TANC2
Gene symbol Tanc2
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MFRNSLKMLL TGGKSSRKNR SSDGGSEEPP DRRQSSVDSR QSRSGPGGIS TESDCAFEPD 60
YAVPALPVSE GMQHIRIMEG VSRSLPSSPL LTHQSISVRL QPVKKLTAPL RKAKFVESPR 120
IPESELGSPT LTSAQKLDVD AYCPGDVEQE LGPPPSVDEA ANTLMTRLGF LLGEKVTEVQ 180
PGDQYSMEVQ DENQTSAITQ RISPCSTLTS STASPPASSP CSTLPPVSTN ATAKDCSYGA 240
VTSPTSTLES RDSGIIATLT NYSENMERTK YVGEAGKELG SGGNLKPWQS QKSSMDSCLY 300
RVDENMAAST YSLNKIPERN LETVLSQSVQ SIPLYLMPRP NSVAATSSAH LEDLAYLDEQ 360
RHTPLRTSLR MPRQSMSGAR TQQDLRVRFA PYRPPDISLK PLLFEVPSIT TESVFVGRDW 420
VFHEIDAQLQ SSNASVNQGV VIVGNIGFGK TAIISRLVAL SCHGTRMRQI ASDSPHASPK 480
HVDANRELPL TQAPSAHSSI ASGSCPGTPE MRRRQEEAMR RLASQVVAYH YCQADNAYTC 540
LVPEFVHNVA ALLCRSPQLT AYREQLLREP HLQSMLSLRS CVQDPMASFR RGVLEPLENL 600
HKERKIPDED FIILIDGLNE AEFHKPDYGD TIVSFLSKMI GNFPSWLKLI VTVRTSLQEI 660
TKLLPFHRIF LDRLEENEAI DQDLQAYILH RIHSSSEIQN NISLNGKMDN TTFGKLSSHL 720
KTLSQGSYLY LKLTFDLIEK GYLVLKSSSY KVVPVSLSEV YLLQCNMKFP TQSSFDRVMP 780
LLNVAVASLH PLTDEHIFQA INAGSIEGTL EWEDFQQRME NLSMFLIKRR DMTRMFVHPS 840
FREWLIWREE GEKTKFLCDP RSGHTLLAFW FSRQEGKLNR QQTIELGHHI LKAHIFKGLS 900
KKVGVSSSIL QGLWISYSTE GLSMALASLR NLYTPNIKVS RLLILGGANI NYRTEVLNNA 960
PILCVQSHLG YTEMVALLLE FGANVDASSE SGLTPLGYAA AAGFLSIVVL LCKKRAKVDH 1020
LDKNGQCALV HAALRGHLEV VKFLIQCDWT MAGQQQGVFK KSQAIQQALI AAASMGYTEI 1080
VSYLLDLPEK DEEEVERAQI NSFDSLWGET ALTAAAGRGK LDVCRLLLEQ GAAVAQPNRR 1140
GAVPLFSTVR QGHWQIVDLL LTHGADVNMA DKQGRTPLMM AASEGHLGTV DFLLAQGASI 1200
ALMDKEGLTA LSWACLKGHL SVVRSLVDNG AATDHADKNG RTPLDLAAFY GDAEVVQFLV 1260
DHGAMIEHVD YSGMRPLDRA VGCRNTSVVV TLLKKGAKIG CQTLPSRPRG PATWAMATSK 1320
PDIMIILLSK LMEEGDMFYK KGKVKEAAQR YQYALKKFPR EGFGEDLKTF RELKVSLLLN 1380
LSRCRRKMND FGMAEEFATK ALELKPKSYE AYYARARAKR SSRQFAAALE DLKEAIKLCP 1440
NNREIQRLLM RVEEECRQMQ QQQQPPPPPQ QPPEELPEEE TEPEPQPEDI YSVQDIFEEE 1500
YLEQDVENVS IGLQTEARPS QGLPVIQSPP SSPAHRDSAY ISSSPLGSHQ VFDFRSNSSV 1560
GSPTRQGYQS TSPALSPTHQ NSHYRPSPPH TSPAHQGASY RFSPPPVGGQ GKEYPSPPPS 1620
PLRRGPQYRA SPPAESMSIY RSQSGSPVRY QQEANVSQLP GRPKSPLSKM AQRPYQMPQL 1680
PVAVPQQGLR LQPAKAQIVR SNQPSSAVHS STVIPTGAYG QVAHPMASKY QSSQGDMGVS 1740
QSRLVYQGSI GGIVGDGRPV QHVQASLSAG AICQHGGLTK EDLPQRPSSA YRGGMRYSQT 1800
PQIGRSQSAS YYPVCHSKLD LERSSSQLGS PDVSHLIRRP ISVNPNEIKP HPPTPRPLLH 1860
SQSVGLRFSP SSNSISSTAN LTPTFRPSSS IQQMEIPLKP AYDRSCDELS PVSPTQGGYP 1920
SEPTRSRTTP FMGIIDKTAR TQQYPHLHQQ NRTWAVSSVD TVLSPTSPGN LSQPESFSPP 1980
SSISNIAFYN KTNNAQNGHL LEDDYYSPHG MLANGSRGDL LERVSQASSY PDVKVARTLP 2040
VAQAYQDNLY RQLSRDSRQG QTSPIKPKRP FVESNV 2076

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTANC2F1PAF9Canis lupus familiarisPredictionMore>>
1:1 orthologTANC2A0A452DN91Capra hircusPredictionMore>>
1:1 orthologTANC226115Q9HCD6Homo sapiensPublicationMore>>
1:1 orthologTanc277097A2A690Mus musculusPredictionMore>>
1:1 orthologTANC2454784H2QDM5Pan troglodytesPredictionMore>>
1:1 orthologTANC2F1RRV1Sus scrofaPredictionMore>>
1:1 orthologTanc2303599A0A0G2K9J0Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0043197 dendritic spine
GO:0001701 in utero embryonic development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0040 ANK repeat
KW-1185 Reference proteome
KW-0802 TPR repeat

Interpro

InterPro ID InterPro Term
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR027417 P-loop_NTPase
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

PROSITE

PROSITE ID PROSITE Term
PS50297 ANK_REP_REGION
PS50088 ANK_REPEAT
PS50005 TPR
PS50293 TPR_REGION

Pfam

Pfam ID Pfam Term
PF00023 Ank
PF12796 Ank_2
PF13181 TPR_8