Gene: TANC2

Basic information

Tag Content
Uniprot ID F1PAF9
Entrez ID
Genbank protein ID
Genbank nucleotide ID XM_014116396.1
Ensembl protein ID ENSCAFP00000019244
Ensembl nucleotide ID ENSCAFG00000013052
Gene name Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Gene symbol TANC2
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MFRNSLKMLL TGGKSSRKNR SSDGGSEEPP DRRQSSVDSR QSRSGQGGIS TESDCAFEPD 60
YAVPPLPVSE GMQHIRIMEG MSRSLPSSPL LTHQSISVRL QPVKKLTAPL RKAKFVESPR 120
IPESELGSPT LASAQKLDVD AYCPGDAEQE LGPPPSVDEA ANTLMTRLGF LLGEKVTEVQ 180
PGDQYNMEVQ DENQTSAITQ RISPCSTLTS STASPPASSP CSTLPPVSTN ATAKDCSYGA 240
VTSPTSTLES RDSGIIATLT SYSENVERTK YVGESSKELG SGGNLKPWQS QKSSMDSCLY 300
RVDENMTAST YSLNKIPERN LESVLSQSVQ SIPLYLMPRP NSVAATSSAH LEDLAYLDEQ 360
RHTPLRTSLR MPRQSMGGAR TQQDLRVHFA PYRPPDISLK PLLFEVPSIT TESVFVGRDW 420
VFHEIDAQLQ SSNASVNQGV VIVGNIGFGK TAIISRLVAL SCHGTRMRQI ASDSPHASPK 480
HVDANRELPL TQPPSAHSSI PSGSCPGTPE MRRRQEEAMR RLASQVVAYH YCQADNAYTC 540
LVPEFVHNVA ALLCRSPQLA AYREQLLREP HLQSMLSLRS CVQDPMASFR RGVLEPLENL 600
HKERKIPDED FIILIDGLNE AEFHKPDYGD TIVSFLSKMI GKFPSWLKLI VTVRTSLQEI 660
TKLLPFHRIF LDRLEENEAI DQDLQAYILH RIHSSSEIQN NISLNGKMDN TTFGKLSSHL 720
KTLSQGSYLY LKLTFDLIEK GYLVLKSSSY KVVPVSLSEV YLLQCNMKFP TQSSFDRVMP 780
LLNVAVASLH PLTDEHIFQA INAGSIEGTL EWEDFQQRME NLSMFLIKRR DMTRMFVHPS 840
FREWLIWREE GEKTKFLCDP RSGHTLLAFW FSRQEGKLNR QQTIELGHHI LKAHIFKGLS 900
KKVGVSSSIL QGLWISYSTE GLSMALASLR NLYTPNIKVS RLLILGGANI NYRTEVLNNA 960
PILCVQSHLG YTEMVALLLE FGANVDASSE SGLTPLGYAA AAGYLSIVVL LCKKRAKVDH 1020
LDKNGQCALV HAALRGHLEV VKFLIQCDWT MAGQQQGVFK KSHAIQQALI AAASMGYTEI 1080
VSYLLDLPEK DEEEVERAQI NSFDSLWGET ALTAAAGRGK LEVCRLLLEQ GAAVAQPNRR 1140
GAVPLFSTVR QGHWQIVDLL LTHGADVNMA DKQGRTPLMM AASEGHLGTV DFLLAQGASI 1200
ALMDKEGLTA LSWACLKGHL SVVRSLVDNG AATDHADKNG RTPLDLAAFY GDAEVVQFLV 1260
DHGAMIEHVD YSGMRPLDRA VGCRNTSVVV TLLKKGAKIG PATWAMATSK PDIMIILLSK 1320
LMEEGDMFYK KGKVKEAAQR YQYALKKFPR EGFGEDLKTF RELKVSLLLN LSRCRRKMND 1380
FGMAEEFATK ALELKPKSYE AYYARARAKR SSRQFAAALE DLNEAIKLCP NNREIQRLLL 1440
RVEEECRQMQ PPPPPQQPPQ PPLPEEAEPE PQHEDIYSVQ DIFEEEYLEQ DVENVSIGLQ 1500
TEARPSQGLP IIQSPPSSPA HRDSAYISSS PLGSHQVFDF RSSSSVGSPT RQGYQSTSPA 1560
LSPTHQNSHY RPSPPHTSPA HQSGSYRFSP PPVGGQGKEY PSPPPSPLRR GPQYRASPPA 1620
ESMSIYRSQS GSPVRYQQET SVSQLPGRPK SPLSKMAQRP YQMPQLPVAV PQQGLRLQPA 1680
KAQIVRSNQP SSAVHSSTVI STGAYGQVAH SMASKYQSSQ GDMGVSQSRL VYQGSIGGIV 1740
GDGRPVQHVQ ASLSAGAICQ HGGLTKEDLP QRPSSAYRGG MRYSQTPQIG RSQSASYYPV 1800
CHSKLDLERS SSQLGSPDVS HLIRRPISVN PNEIKPHPPT PRPLLHSQSV GLRFSPSSNS 1860
ISSASNLTPT FRPSSSIQQM EIPLKPAYDR SCDELSPVSP TQGGYPSEPT RSRTTPFMGI 1920
IDKTARTQQY PHLHQQNRTW AVSSVDTVLS PTSPGNLPQP ESFSPPSSIS NIAFYNKTNN 1980
AQNGHLLEDD YYSPHGMLAN GSRGDLLERV GQASSYPDVK VARTLPVAQA YQDNLYRQLS 2040
RDSRQGQTSP IKPKRPFVES NV 2062

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTANC2F1PAF9Canis lupus familiarisPredictionMore>>
1:1 orthologTANC2A0A452DN91Capra hircusPredictionMore>>
1:1 orthologTANC226115Q9HCD6Homo sapiensPublicationMore>>
1:1 orthologTanc277097A2A690Mus musculusPredictionMore>>
1:1 orthologTANC2454784H2QDM5Pan troglodytesPredictionMore>>
1:1 orthologTANC2F1RRV1Sus scrofaPredictionMore>>
1:1 orthologTanc2303599A0A0G2K9J0Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0040 ANK repeat
KW-1185 Reference proteome
KW-0802 TPR repeat

Interpro

InterPro ID InterPro Term
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR027417 P-loop_NTPase
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

PROSITE

PROSITE ID PROSITE Term
PS50297 ANK_REP_REGION
PS50088 ANK_REPEAT
PS50005 TPR
PS50293 TPR_REGION

Pfam

Pfam ID Pfam Term
PF00023 Ank
PF12796 Ank_2
PF13181 TPR_8