Gene: TANC2

Basic information

Tag Content
Uniprot ID A0A452DN91
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000001230
Ensembl nucleotide ID ENSCHIG00000002001
Gene name Uncharacterized protein
Gene symbol TANC2
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MFRNSLKMLL TGGKSSRKNR SSDGGSEEPP DRRQSSVDSR QSRSGQGGIS TESDCAFEPD 60
YAVPPLPVSE GDAEQDLGPP PSVDEAANTL MTRLGFLLGE KVTEVQPGDQ YSMEVQDENQ 120
TSAITQRISP CSTLTSSTAS PPASSPCSTL PPVSTSATAK DGSYGAVTSP TSTLESRDSG 180
IIATLTSYSE NMERTKYVGE SSKELGSGGN LKPWQSQKSS MDSCLYRVDE NMTASTYSLN 240
KIPERNLETV LSQSVQSIPL YLMPRPNSVA ATSSAHLEDL AYLDEQRHTP LRTSLRMPRQ 300
SMAGARTQQD LRVRFAPYRP PDISLKPLLF EVPSITTESV FVGRDWVFHE IDAQLQSSNA 360
SVNQGVVIVG NIGFGKTAII SRLVALSCHG TRMRQIASDS PHASPKHVDA NRELPLTQPP 420
SAHSSITSGS CPGTPEMRRR QEEAMRRLAS QVVAYHYCQA DNAYTCLVPE FVHNVAALLC 480
RSPQLAAYRE QLLREPHLQS MLSLRSCVQD PMASFRRGVL EPLENLHKER KIPDEDFIIL 540
IDGLNEAEFH KPDYGDTIVS FLSKMIGKFP SWLKLIVTVR TSLQEITKLL PFHRIFLDRL 600
EENEAIDQDL QAYILHRIHS SSEIQNNISL NGKMDNTTFG KLSSHLKTLS QGSYLYLKLT 660
FDLIEKGYLV LKSSSYKVVP VSLSEVYLLQ CNMKFPTQSS FDRVMPLLNV AVASLHPLTD 720
EHIFQAINAG SIEGTLEWED FQQRMENLSM FLIKRRDMTR MFVHPSFREW LIWREEGEKT 780
KFLCDPRSGH TLLAFWFSRQ EGKLNRQQTI ELGHHILKAH IFKGLSKKVG VSSSILQGLW 840
ISYSTEGLSM ALASLRNLYT PNIKVSRLLI LGGANINYRT EVLNNAPILC VQSHLGYTEM 900
VALLLEFGAN VDASSESGLT PLGYAAAAGF LSIVVLLCKK RAKVDHLDKN GQCALVHAAL 960
RGHLEVVKFL IQCDWTMAGQ QQGVFKKSHA IQQALIAAAS MGYTEIVSYL LDLPEKDEEE 1020
VERAQINSFD SLWGETALTA AAGRGKLEVC RLLLEQGAAV AQPNRRGAVP LFSTVRQGHW 1080
QIVDLLLTHG ADVNMADKQG RTPLMMAASE GHLGTVDFLL AQGASIALMD KEGLTALSWA 1140
CLKGHLSVVR SLVDNGAATD HADKNGRTPL DLAAFYGDAE VVQFLVDHGA MIEHVDYSGM 1200
RPLDRAVGCR NTSVVVTLLK KGAKIGPATW AMATSKPDIM IILLSKLMEE GDMFYKKGKV 1260
KEAAQRYQYA LKKFPREGFG EDLKTFRELK VSLLLNLSRC RRKMNDFGMA EEFATKALEL 1320
KPKSYEAYYA RARAKRSSSR QFAAALEDLN EAIKLCPNNR EIQRLLLRVE EECRQMQQQP 1380
PVQQQPPQQQ LPEEAEPEPQ HEDIYSVQDI LEEEFLEQDV ENVSIGLQTE ARPSQGLPII 1440
QSPPSSPAHR DSAYISGSPL GSHQVFDFRS SSSVGSPTRQ SYQSSSPALS PTHQNSHYRP 1500
SPPHTSPAHQ GGSYRFSPPP VGGPGKEYPS PPPSPLRRGP QYRASPPAES MSVYRSQSGS 1560
PVRYQQETNV SQLPGRPKSP LSKMAQRPYQ MPQLPVAVPQ PGLRLQPAKA QIVRSNQPSS 1620
AVHSSTVIST GAYGQVAHSM ASKYQSSQGD IGVSQSRLVY QGSIGGIVGD GRPVQHVQAS 1680
LSAGAICQHG GLTKEDLPQR PSSAYRGGMR YSQTPQIGRS QSASYYPVCH SKLDLERSSS 1740
QLGSPDVSHL IRRPISVNPN EIKPHPPTPR PLLHSQSVGL RFSPSSNSIS SASNLTPTFR 1800
PSSSIQQMEI PLKPAYDRSC DELSPVSPTQ GGYPSEPTRS RTTPFMGIID KTARTQQYPH 1860
LHQQNRTWAV SSVDTVLSPT SPGGLPQPES FSPPSSISNI AFYNKTNNAQ NGHLLEDDYY 1920
SPHGMLANGS RGDLLERVSQ ASSYPDVKVA RTLPVAQAYQ DNLYRQLSRD SRQGQTSPIK 1980
PKRPFVESNV

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTANC2F1PAF9Canis lupus familiarisPredictionMore>>
1:1 orthologTANC2A0A452DN91Capra hircusPredictionMore>>
1:1 orthologTANC226115Q9HCD6Homo sapiensPublicationMore>>
1:1 orthologTanc277097A2A690Mus musculusPredictionMore>>
1:1 orthologTANC2454784H2QDM5Pan troglodytesPredictionMore>>
1:1 orthologTANC2F1RRV1Sus scrofaPredictionMore>>
1:1 orthologTanc2303599A0A0G2K9J0Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0043197 dendritic spine
GO:0001701 in utero embryonic development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0040 ANK repeat
KW-1185 Reference proteome
KW-0802 TPR repeat

Interpro

InterPro ID InterPro Term
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR027417 P-loop_NTPase
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

PROSITE

PROSITE ID PROSITE Term
PS50297 ANK_REP_REGION
PS50088 ANK_REPEAT
PS50005 TPR
PS50293 TPR_REGION

Pfam

Pfam ID Pfam Term
PF00023 Ank
PF12796 Ank_2
PF13181 TPR_8