Gene: TANC2

Basic information

Tag Content
Uniprot ID F1RRV1
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000018330
Ensembl nucleotide ID ENSSSCG00000017298
Gene name Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Gene symbol TANC2
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MESKSTLILG SLAPLRKAKF VESPRIPESE LGSPTLTSAQ KLDVDAYCPG DAEQELGPPP 60
SVDEAANTLM TRLGFLLGEK VTEVQPGDQY NMEVQDENQT SAITQRISPC STLTSSTASP 120
PASSPCSTLP PVSTSAAAKD CSYGAVTSPT STLESRDSGI IATLTSYSEN MERSKYVGES 180
SKELGSGGNV KPWQSQKSSM DSCLYRVDEN MTASTYSLNK IPERNLETVL SQSVQSIPLY 240
LMPRPNSVAA TSSAHLEDLA YLDEQRHTPL RTSLRMPRQS MAGARTQQDL RVRFAPYRPP 300
DISLKPLLFE VPSITTESVF VGRDWVFHEI DAQLQSSNAN VNQGVVIVGN IGFGKTAIIS 360
RLVALSCHGT RMRQIASDSP HASPKHVDAN RELPLTQPPS AHSSITSGSC PGTPEMRRRQ 420
EEAMRRLASQ VVAYHYCQAD NAYTCLVPEF VHNVAALLCR SPQLAAYREQ LLREPHLQSM 480
LSLRSCVQDP MASFRRGVLE PLENLHKERK IPDEDFIILI DGLNEAEFHK PDYGDTIVSF 540
LSKMIGKFPS WLKLIVTVRT SLQEITKLLP FHRIFLDRLE ENEAIDQDLQ AYILHRIHSS 600
SEIQNNISLN GKMDNTTFGK LSSHLKTLSQ GSYLYLKLTF DLIEKGYLVL KSSSYKVVPV 660
SLSEVYLLQC NMKFPTQSSF DRVMPLLNVA VASLHPLTDE HIFQAINAGS IEGTLEWEDF 720
QQRMENLSMF LIKRRDMTRM FVHPSFREWL IWREEGEKTK FLCDPRSGHT LLAFWFSRQE 780
GKLNRQQTIE LGHHILKAHI FKGLSKKVGV SSSILQGLWI SYSTEGLSMA LASLRNLYTP 840
NIKVSRLLIL GGANINYRTE VLNNAPILCV QSHLGYTEMV ALLLEFGANV DASSESGLTP 900
LGYAAAAGFL SIVVLLCKKR AKVDHLDKNG QCALVHAALR GHLEVVKFLI QCDWTMAGQQ 960
QGVFKKSHAI QQALIAAASM GYTEIVSYLL DLPEKDEEEV ERAQINSFDS LWGETALTAA 1020
AGRGKLEVCR LLLEQGAAVA QPNRRGAVPL FSTVRQGHWQ IVDLLLTHGA DVNMADKQGR 1080
TPLMMAASEG HLGTVDFLLA QGASIALMDK EGLTALSWAC LKGHLSVVRS LVDNGAATDH 1140
ADKNGRTPLD LAAFYGDAEV VQFLVDHGAM IEHVDYSGMR PLDRAVGCRN TSVVVTLLKK 1200
GAKIGCQTLP SRPRGPATWA MATSKPDIMI ILLSKLMEEG DMFYKKGKVK EAAQRYQYAL 1260
KKFPREGFGE DLKTFRELKV SLLLNLSRCR RKMNDFGMAE EFATKALELK PKSYEAYYAR 1320
ARAKRSSRQF AAALEDLNEA IKLCPNNREI QRLLLRVEEE CRQMQQQPPQ QPQQQLPEET 1380
EPEPQHEDIY SVQDIFEEEY LEQDVENVSI GLQTEARPSQ GLPIIQSPPS SPAHRDSAYI 1440
SSSPLGSHQV FDFRSSSSVG SPTRQSFQST SPALSPTHQN SHYRPSPPHT SPAHQGGSYR 1500
FSPPPVGGQG KEYPSPPPSP LRRGPQYRAS PPAESMSVYR SQSGSPVRYQ QEASVGQLPG 1560
RPKSPLSKMA QRPYQMPQLP VAVPQQGLRL QPAKAQIVRS NQPSSAVHSS TVISTGAYGQ 1620
VAHSMASKYQ SSQGDIGVSQ SRLVYQGSIG GIVGDGRPVQ HVQASLSAGA ICQHGGLAKE 1680
DLPQRPSSAY RGGMRYSQTP QIGRSQSASY YPVCHSKLDL ERSSSQLGSP DVSHLIRRPI 1740
SVNPSEIKPH PPTPRPLLHS QSVGLRFSPS SNSISSAANL TPTFRPSSSI QQMEIPLKPA 1800
YDRSCDELSP VSPTQGGYPS EPTRSRTTPF MGIIDKTART QQYPHLHQQN RTWAVSSVDT 1860
VLSPTSPGNL PQPESFSPPS SISNIAFYNK TNNAQNGHLL EDEYYSPHGM LANGSRGDLL 1920
ERVSQASSYP DVKVARTLPV AQAYQDNLYR QLSRDSRQGQ TSPIKPKRPF VESNV 1975

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTANC2F1PAF9Canis lupus familiarisPredictionMore>>
1:1 orthologTANC2A0A452DN91Capra hircusPredictionMore>>
1:1 orthologTANC226115Q9HCD6Homo sapiensPublicationMore>>
1:1 orthologTanc277097A2A690Mus musculusPredictionMore>>
1:1 orthologTANC2454784H2QDM5Pan troglodytesPredictionMore>>
1:1 orthologTANC2F1RRV1Sus scrofaPredictionMore>>
1:1 orthologTanc2303599A0A0G2K9J0Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0040 ANK repeat
KW-1185 Reference proteome
KW-0802 TPR repeat

Interpro

InterPro ID InterPro Term
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR027417 P-loop_NTPase
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

PROSITE

PROSITE ID PROSITE Term
PS50297 ANK_REP_REGION
PS50088 ANK_REPEAT
PS50005 TPR
PS50293 TPR_REGION

Pfam

Pfam ID Pfam Term
PF00023 Ank
PF12796 Ank_2
PF13181 TPR_8