| Tag | Content |
|---|---|
| Uniprot ID | A0A0R4IR84; A0A0R4IP80; |
| Entrez ID | 570459 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_017352818.1; NM_001324455.1; XM_009295591.2; |
| Ensembl protein ID | ENSDARP00000137411; ENSDARP00000137017; |
| Ensembl nucleotide ID | ENSDARG00000103606 |
| Gene name | [Heparan sulfate]-glucosamine N-sulfotransferase |
| Gene symbol | ndst1b |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MMLMCGRVRR LFRQLTLQTS LLLLFLFCMV SVLISAYFLY GVKRELEPAG AGGVVVPEEG 60 TADWEDPRAT PSPPSARVLP ARTAKPADMS RTDPVVLVFV ESLYSQLGQD IVAILESGRF 120 RYQTEIAPGK GDMPTLTDKN RGRFTLVIYE NILKYVNLDA WNRELLDKYC VEYGVGIIGF 180 FKANENSLQS AQLKGFPLFL HSNLGLRDCS VNPKSPLLFI TKAREVEHGP LPGDDWTVFQ 240 SNHTTYEPVL LARGRSTEAS GAPGPLHAAV VQDLGLHDGI QRVLFGNNLN FWLHKLVLVD 300 AVSFLTGKRL SLALERYILV DIDDIFVGKE GTRMKVSDVK ALLETQNELR NHVPNFTFNL 360 GFSGKFFHAG TDEEDLGDDL LLSYSKEFWW FPHMWSHMQP HLFHNQSVLA EQMLLNHKFA 420 EEHGIPTNMG YAVAPHHSGV YPIHLQLYEA WKKVWGIKVT STEEYPHLKP ARFRRGFVHS 480 GISVLPRQTC GLFTHTIFYN EYPGGSKELD KLIYGGELFL TVLLNPISIF MTHLSNYGND 540 RLGLYTFKNL VKFVQMWTNL SLQTLPPVQL AQKYFQIFPE ERDPIWQDPC EDKRHKDIWS 600 KEKTCDRFPK LLIIGPQKTG TTALYLFLSM HSDLTSNYPS KETFEEIQFF NGRNYHKGID 660 WYMEHFPLPS NTSSDFYFEK SANYFDSEVA ARRAAALLPK AKIITILINP ADRAYSWYQH 720 QRAHDDPVAQ KYTFHDVITA GRDAPIKLRV LQSRCLVPGL YATHLQRWLT HYHPSQILVL 780 DGQMLRTEPA SVMDKIQKFL GLINTLNYHK ILAFDPKKGF WCQLLDGGKT KCLGKSKGRR 840 YPDMDVDSRT FLREYYHEHN IELSKLLYKM GQPLPSWLRE ELLHSR 886 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NDST1 | 514172 | E1BCG5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NDST1 | 102174299 | A0A452EZE5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NDST1 | 3340 | P52848 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ndst1 | 15531 | Q3UHN9 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NDST1 | 462194 | H2R584 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NDST1 | M3V841 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | NDST1 | 100344304 | G1T1F7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Ndst1 | 29633 | Q02353 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ndst1b | 570459 | A0A0R4IR84 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005794 | Golgi apparatus |
| GO:0000139 | Golgi membrane |
| GO:0016021 | integral component of membrane |
| GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity |
| GO:0019213 | deacetylase activity |
| GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process |
| GO:0030210 | heparin biosynthetic process |
| GO:0051923 | sulfation |
| GO:0001570 | vasculogenesis |