Gene: NDST1

Basic information

Tag Content
Uniprot ID G1T1F7
Entrez ID 100344304
Genbank protein ID
Genbank nucleotide ID XM_008255264.2; XM_002710310.3;
Ensembl protein ID ENSOCUP00000009903
Ensembl nucleotide ID ENSOCUG00000011515
Gene name N-deacetylase and N-sulfotransferase 1
Gene symbol NDST1
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MPALACLRRL CRHVSPQAVL FLLFVFCLFS VFVSAYYLYG WKRGLEPSAD APEPDCGDPP 60
PVAPSRLLPL KPVQAATPSR TDPLVLVFVE SLYSQLGQEV VAILESSRFK YRTEIAPGKG 120
DMPTLTDKGR GRFALIIYEN ILKYVNLDAW NRELLDKYCV AYGVGIIGFF KANENSLLSA 180
QLKGFPLFLH SNLGLKDCSI NPKSPLLYVT RPSEVEKGVL PGEDWTVFQS NHSTYEPVLL 240
AKTRSSESIP HLGADAGLHA ALHATVVQDL GLHDGIQRVL FGNNLNFWLH KLVFVDAVAF 300
LTGKRLSLPL DRYILVDIDD IFVGKEGTRM KVEDVKALFD TQNELRTHIP NFTFNLGYSG 360
KFFHTGTDAE DAGDDLLLSY VKEFWWFPHM WSHMQPHLFH NQSVLAEQMA LNKKFAVEHG 420
IPTDMGYAVA PHHSGVYPVH VQLYEAWKQV WSIRVTSTEE YPHLKPARYR RGFIHNGIMV 480
LPRQTCGLFT HTIFYNEYPG GSSELDKIIN GGELFLTVLL NPISIFMTHL SNYGNDRLGL 540
YTFKHLVRFL HSWTNLQLQT LPPVQLARKY FQIFSEEKDP LWQDPCEDKR HKDIWSKEKT 600
CDRFPKLLII GPQKTGTTAL YLFLGMHPDL SSNYPSSETF EEIQFFNGHN YHKGIDWYME 660
FFPIPSNTTS DFYFEKSANY FDSEVAPRRA AALLPKAKIL TILINPADRA YSWYQHQRAH 720
DDAVALKYTF HEVITAGPDA SSKLRTLQNR CLVPGWYAVH IERWLSAFHA NQILVLDGKL 780
LRTEPAKVMD TVQKFLGVTN TIDYHKTLAF DPKKGFWCQL LEGGKTKCLG KSKGRKYPEM 840
DLDSRAFLRD YYRDHNIELS KLLYKMGQTL PTWLREDLQN TR 882

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologNDST1514172E1BCG5Bos taurusPredictionMore>>
1:1 orthologNDST1102174299A0A452EZE5Capra hircusPredictionMore>>
1:1 orthologNDST13340P52848Homo sapiensPredictionMore>>
1:1 orthologNdst115531Q3UHN9CPOMus musculusPublicationMore>>
1:1 orthologNDST1462194H2R584Pan troglodytesPredictionMore>>
1:1 orthologNDST1M3V841Sus scrofaPredictionMore>>
1:1 orthologNDST1100344304G1T1F7Oryctolagus cuniculusPredictionMore>>
1:1 orthologNdst129633Q02353Rattus norvegicusPredictionMore>>
1:1 orthologndst1b570459A0A0R4IR84Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity
GO:0016787 hydrolase activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR021930 Heparan_SO4_deacetylase
IPR037359 NST/OST
IPR027417 P-loop_NTPase
IPR000863 Sulfotransferase_dom

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF12062 HSNSD
PF00685 Sulfotransfer_1